Highly efficient asymmetric synthesis of 3-indolyl(hydroxy)acetates via Friedel-Crafts alkylation of indoles

Journal of Organic Chemistry

Volumn 74, Issue 17, 2009, Pages 6878-6880

  Hui, Yonghai ^a   Zhang, Qi ^a   Jiang, Jun ^a   Lin, Lili ^a   Liu, Xiaohua ^a   Feng, Xiaoming ^a  

^a China   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ASYMMETRIC SYNTHESIS; CHEMICAL EQUATIONS; ENANTIOSELECTIVE; ETHYL GLYOXYLATE; FRIEDEL-CRAFTS ALKYLATION; GOOD YIELD; HIGH ENANTIOSELECTIVITY;

ALKYLATION; ENANTIOSELECTIVITY; SCANDIUM; SCANDIUM COMPOUNDS;

HYDROCARBONS;

ACETIC ACID DERIVATIVE; GLYOXYLIC ACID DERIVATIVE; INDOLE DERIVATIVE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL MODIFICATION; ENANTIOSELECTIVITY; FRIEDEL CRAFTS REACTION; STEREOCHEMISTRY; SYNTHESIS;

ACETATES; ALKYLATION; CATALYSIS; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; GLYOXYLATES; INDOLES; LIGANDS; METALS; MODELS, CHEMICAL; OXIDES; SOLVENTS; STEREOISOMERISM;

EID: 69549128248     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo901425z     Document Type: Article

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54. 2H: 92% yield, 87% ee.