A Gene Expression Model of Intrinsic Tumor Radiosensitivity: Prediction of Response and Prognosis After Chemoradiation

International Journal of Radiation Oncology Biology Physics

Volumn 75, Issue 2, 2009, Pages 489-496

  Eschrich, Steven A ^a   Pramana, Jimmy ^b   Zhang, Hongling ^a   Zhao, Haiyan ^a   Boulware, David ^a   Lee, Ji Hyun ^a   Bloom, Gregory ^a   Rocha Lima, Caio ^c   Kelley, Scott ^a   Calvin, Douglas P ^a   Yeatman, Timothy J ^a   Begg, Adrian C ^b   Torres Roca, Javier F ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Chemoradiation; Gene expression; Intrinsic radiosensitivity; Predictive assay; Systems biology

Indexed keywords

CHEMORADIATION; CONCURRENT CHEMORADIATION; DATA SETS; ESOPHAGEAL CANCER; HEAD-AND-NECK CANCER; HIGH INDEX; HUMAN CANCER CELLS; INTRINSIC RADIOSENSITIVITY; LINEAR REGRESSION ALGORITHMS; LOCOREGIONAL CONTROL; POSITIVE PREDICTIVE VALUES; PREDICTIVE ASSAY; RADIATION ONCOLOGY; RADIORESISTANCE; RECTAL CANCER; SURVIVAL FRACTIONS; SYSTEMS BIOLOGY; TREATMENT RESPONSE;

BIOACTIVITY; CELL CULTURE; CELL MEMBRANES; GENE EXPRESSION; TUMORS;

INGOT MOLDS;

RAS PROTEIN;

AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; ESOPHAGUS CANCER; ESOPHAGUS RESECTION; GENE EXPRESSION; HUMAN; PRIORITY JOURNAL; PROGNOSIS; RADIATION DOSE; RADIOSENSITIVITY; RECTUM CANCER; RECTUM RESECTION; SYSTEMS BIOLOGY;

AGED; AGED, 80 AND OVER; ALGORITHMS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; ESOPHAGEAL NEOPLASMS; FEMALE; GENE EXPRESSION; HEAD AND NECK NEOPLASMS; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; MODELS, GENETIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROGNOSIS; PROSPECTIVE STUDIES; RADIATION TOLERANCE; RECTAL NEOPLASMS; TOPOTECAN;

EID: 69549116364     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.06.014     Document Type: Article

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