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Volumn 76, Issue 3, 2009, Pages 612-617

Adenovirus-transduced human butyrylcholinesterase in mouse blood functions as a bioscavenger of chemical warfare nerve agents

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CHEMICAL WARFARE AGENT; CHOLINESTERASE; DIMER; ENZYME ANTIBODY; O ETHYL S 2 N,N DIISOPROPYLAMINOETHYLMETHYLPHOSPHONOTHIOLATE; OLIGOMER; RECOMBINANT HUMAN CHOLINESTERASE; SOMAN; TETRAMER; UNCLASSIFIED DRUG;

EID: 69549113501     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.109.055665     Document Type: Article
Times cited : (14)

References (38)
  • 1
    • 0031879541 scopus 로고    scopus 로고
    • Prophylaxis against soman inhalation toxicity in guinea pigs by pretreatment alone with human serum butyrylcholinesterase
    • DOI 10.1006/toxs.1998.2463
    • Allon N, Raveh L, Gilat E, Cohen E, Grunwald J, and Ashani Y (1998) Prophylaxis against soman inhalation toxicity in guinea pigs by pretreatment alone with human serum butyrylcholinesterase. Toxicol Sci 43:121-128. (Pubitemid 28363385)
    • (1998) Toxicological Sciences , vol.43 , Issue.2 , pp. 121-128
    • Allon, N.1    Raveh, L.2    Gilat, E.3    Cohen, E.4    Grunwald, J.5    Ashani, Y.6
  • 2
    • 1342288926 scopus 로고    scopus 로고
    • Estimation of the upper limit of human butyrylcholinesterase dose required for protection against organophosphates toxicity: A mathematically based toxicokinetic model
    • DOI 10.1093/toxsci/kfh012
    • Ashani Y and Pistinner S (2004) Estimation of the upper limit of human butyrylcholinesterase dose required for protection against organophosphates toxicity: a mathematically based toxicokinetic model. Toxicol Sci 77:358-367. (Pubitemid 38262609)
    • (2004) Toxicological Sciences , vol.77 , Issue.2 , pp. 358-367
    • Ashani, Y.1    Pistinner, S.2
  • 3
    • 0025962236 scopus 로고
    • Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice
    • Ashani Y, Shapira S, Levy D, Wolfe AD, Doctor BP, and Raveh L (1991) Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice. Biochem Pharmacol 41:37-41.
    • (1991) Biochem Pharmacol , vol.41 , pp. 37-41
    • Ashani, Y.1    Shapira, S.2    Levy, D.3    Wolfe, A.D.4    Doctor, B.P.5    Raveh, L.6
  • 4
    • 50649118579 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo
    • Chilukuri N, Duysen EG, Parikh K, Sun W, Doctor BP, Lockridge O, and Saxena A (2008a) Adenovirus-mediated gene transfer of human butyrylcholinesterase results in persistent high-level transgene expression in vivo. Chem Biol Interact 175:327-331.
    • (2008) Chem Biol Interact , vol.175 , pp. 327-331
    • Chilukuri, N.1    Duysen, E.G.2    Parikh, K.3    Sun, W.4    Doctor, B.P.5    Lockridge, O.6    Saxena, A.7
  • 5
    • 28744447265 scopus 로고    scopus 로고
    • Polyethylene glycosylation prolongs the circulatory stability of recombinant human butyrylcholinesterase
    • DOI 10.1016/j.cbi.2005.10.013, PII S0009279705002541
    • Chilukuri N, Parikh K, Sun W, Naik R, Tipparaju P, Doctor BP, and Saxena A (2005) Polyethylene glycosylation prolongs the circulatory stability of recombinant human butyrylcholinesterase. Chem Biol Interact 157-158:115-121. (Pubitemid 41757641)
    • (2005) Chemico-Biological Interactions , vol.157-158 , pp. 115-121
    • Chilukuri, N.1    Parikh, K.2    Sun, W.3    Naik, R.4    Tipparaju, P.5    Doctor, B.P.6    Saxena, A.7
  • 6
    • 50649120602 scopus 로고    scopus 로고
    • Effect of polyethylene glycol modification on the circulatory stability and immunogenicity of recombinant human butyrylcholinesterase
    • Chilukuri N, Sun W, Naik RS, Parikh K, Tang L, Doctor BP, and Saxena A (2008b) Effect of polyethylene glycol modification on the circulatory stability and immunogenicity of recombinant human butyrylcholinesterase. Chem Biol Interact 175:255-260.
    • (2008) Chem Biol Interact , vol.175 , pp. 255-260
    • Chilukuri, N.1    Sun, W.2    Naik, R.S.3    Parikh, K.4    Tang, L.5    Doctor, B.P.6    Saxena, A.7
  • 7
    • 50849122970 scopus 로고    scopus 로고
    • A repeated injection of polyethyleneglycol-conjugated recombinant human butyrylcholinesterase elicits immune response in mice
    • Chilukuri N, Sun W, Parikh K, Naik RS, Tang L, Doctor BP, and Saxena A (2008c) A repeated injection of polyethyleneglycol-conjugated recombinant human butyrylcholinesterase elicits immune response in mice. Toxicol Appl Pharmacol 231:423-429.
    • (2008) Toxicol Appl Pharmacol , vol.231 , pp. 423-429
    • Chilukuri, N.1    Sun, W.2    Parikh, K.3    Naik, R.S.4    Tang, L.5    Doctor, B.P.6    Saxena, A.7
  • 8
    • 1542740195 scopus 로고    scopus 로고
    • Delivery of adenoviral vector DNA to mouse liver
    • Connelly S and Mech C (2004) Delivery of adenoviral vector DNA to mouse liver. Methods Mol Biol 246:37-52.
    • (2004) Methods Mol Biol , vol.246 , pp. 37-52
    • Connelly, S.1    Mech, C.2
  • 9
    • 0342947547 scopus 로고
    • Toxicology of some anticholinesterases used as chemical warfare agents - A review
    • (Brzin M, Barnard EA, and Sket D eds) de Gruyter, Berlin, Germany
    • Dacre JC (1984) Toxicology of some anticholinesterases used as chemical warfare agents - a review, in Cholinesterases, Fundamental and Applied Aspects (Brzin M, Barnard EA, and Sket D eds) pp 415-426, de Gruyter, Berlin, Germany.
    • (1984) Cholinesterases, Fundamental and Applied Aspects , pp. 415-426
    • Dacre, J.C.1
  • 10
    • 0028934815 scopus 로고
    • Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: Tolerization of factor IX and vector antigens allows for long-term expression
    • Dai Y, Schwarz EM, Gu D, Zhang WW, Sarvetnick N, and Verma IM (1995) Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression. Proc Natl Acad Sci U S A 92:1401-1405.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 1401-1405
    • Dai, Y.1    Schwarz, E.M.2    Gu, D.3    Zhang, W.W.4    Sarvetnick, N.5    Verma, I.M.6
  • 11
    • 28744449011 scopus 로고    scopus 로고
    • Bioscavengers for the protection of humans against organophosphate toxicity
    • DOI 10.1016/j.cbi.2005.10.024, PII S0009279705002656
    • Doctor BP and Saxena A (2005) Bioscavengers for the protection of humans against organophosphate toxicity. Chem Biol Interact 157-158:167-171. (Pubitemid 41757647)
    • (2005) Chemico-Biological Interactions , vol.157-158 , pp. 167-171
    • Doctor, B.P.1    Saxena, A.2
  • 12
  • 13
    • 0036070598 scopus 로고    scopus 로고
    • Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity
    • Duysen EG, Bartels CF, and Lockridge O (2002) Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity. J Pharmacol Exp Ther 302:751-758.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 751-758
    • Duysen, E.G.1    Bartels, C.F.2    Lockridge, O.3
  • 15
    • 11244266133 scopus 로고    scopus 로고
    • Gene transfer of cocaine hydrolase suppresses cardiovascular responses to cocaine in rats
    • DOI 10.1124/mol.104.006924
    • Gao Y, Atanasova E, Sui N, Pancook JD, Watkins JD, and Brimijoin S (2005) Gene transfer of cocaine hydrolase suppresses cardiovascular responses to cocaine in rats. Mol Pharmacol 67:204-211, 2005. (Pubitemid 40069980)
    • (2005) Molecular Pharmacology , vol.67 , Issue.1 , pp. 204-211
    • Gao, Y.1    Atanasova, E.2    Sui, N.3    Pancook, J.D.4    Watkins, J.D.5    Brimijoin, S.6
  • 16
    • 0013966668 scopus 로고
    • Isolation and physico-chemical characterization of cholinesterase in human serum
    • Haupt H, Heide K, Zwisler O, and Schwick HG (1966) Isolation and physico-chemical characterization of cholinesterase in human serum. Blut 14:65-75.
    • (1966) Blut , vol.14 , pp. 65-75
    • Haupt, H.1    Heide, K.2    Zwisler, O.3    Schwick, H.G.4
  • 19
    • 78651153462 scopus 로고
    • A "direct-coloring" thiocholine method for cholinesterases
    • Karnovsky MJ and Roots L (1964) A "direct-coloring" thiocholine method for cholinesterases. J Histochem Cytochem 12:219-221.
    • (1964) J Histochem Cytochem , vol.12 , pp. 219-221
    • Karnovsky, M.J.1    Roots, L.2
  • 22
    • 42449151347 scopus 로고    scopus 로고
    • Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers
    • DOI 10.1042/BJ20071551
    • Li H, Schopfer LM, Masson P, and Lockridge O (2008) Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers. Biochem J 411:425-432. (Pubitemid 351580195)
    • (2008) Biochemical Journal , vol.411 , Issue.2 , pp. 425-432
    • Li, H.1    Schopfer, L.M.2    Masson, P.3    Lockridge, O.4
  • 23
    • 0023118832 scopus 로고
    • Complete amino acid sequence of human serum cholinesterase
    • Lockridge O, Bartels CF, Vaughan TA, Wong CK, Norton SE, and Johnson LL (1987) Complete amino acid sequence of human serum cholinesterase. J Biol Chem 262:549-557. (Pubitemid 17005217)
    • (1987) Journal of Biological Chemistry , vol.262 , Issue.2 , pp. 549-557
    • Lockridge, O.1    Bartels, C.F.2    Vaughan, T.A.3
  • 24
    • 0018787225 scopus 로고
    • Interchain disulfide bonds and subunit organization in human serum cholinesterase
    • Lockridge O, Eckerson HW, and La Du BN (1979) Interchain disulfide bonds and subunit organization in human serum cholinesterase. J Biol Chem 254:8324-8330.
    • (1979) J Biol Chem , vol.254 , pp. 8324-8330
    • Lockridge, O.1    Eckerson, H.W.2    La Du, B.N.3
  • 26
    • 34247152147 scopus 로고    scopus 로고
    • The role of oximes in the treatment of nerve agent poisoning in civilian casualties
    • Marrs TC, Rice P, and Vale JA (2006) The role of oximes in the treatment of nerve agent poisoning in civilian casualties. Toxicol Rev 25:297-323.
    • (2006) Toxicol Rev , vol.25 , pp. 297-323
    • Marrs, T.C.1    Rice, P.2    Vale, J.A.3
  • 28
    • 0031193319 scopus 로고    scopus 로고
    • The stoichiometry of protection against soman and VX toxicity in monkeys pretreated with human butyrylcholinesterase
    • DOI 10.1006/taap.1997.8160
    • Raveh L, Grauer E, Grunwald J, Cohen E, and Ashani Y (1997) The stoichiometry of protection against soman and VX toxicity in monkeys pretreated with human butyrylcholinesterase. Toxicol Appl Pharmacol 145:43-53. (Pubitemid 27294768)
    • (1997) Toxicology and Applied Pharmacology , vol.145 , Issue.1 , pp. 43-53
    • Raveh, L.1    Grauer, E.2    Grunwald, J.3    Cohen, E.4    Ashani, Y.5
  • 29
    • 0027241301 scopus 로고
    • Human butyrylcholinesterase as a general prophylactic antidote for nerve agent toxicity. in vitro and in vivo quantitative characterization
    • DOI 10.1016/0006-2952(93)90228-O
    • Raveh L, Grunwald J, Marcus D, Papier Y, Cohen E, and Ashani Y (1993) Human butyrylcholinesterase as a general prophylactic antidote for nerve agent toxicity. In vitro and in vivo quantitative characterization. Biochem Pharmacol 45:2465-2474. (Pubitemid 23189540)
    • (1993) Biochemical Pharmacology , vol.45 , Issue.12 , pp. 2465-2474
    • Raveh, L.1    Grunwald, J.2    Marcus, D.3    Papier, Y.4    Cohen, E.5    Ashani, Y.6
  • 30
    • 0031890563 scopus 로고    scopus 로고
    • Role of oligosaccharides in the pharmacokinetics of tissue-derived and genetically engineered cholinesterases
    • Saxena A, Ashani Y, Raveh L, Stevenson D, Patel T, and Doctor BP (1998) Role of oligosaccharides in the pharmacokinetics of tissue-derived and genetically engineered cholinesterases. Mol Pharmacol 53:112-122. (Pubitemid 28068378)
    • (1998) Molecular Pharmacology , vol.53 , Issue.1 , pp. 112-122
    • Saxena, A.1    Ashani, Y.2    Raveh, L.3    Stevenson, D.4    Patel, T.5    Doctor, B.P.6
  • 31
    • 28744450575 scopus 로고    scopus 로고
    • Human serum butyrylcholinesterase: In vitro and in vivo stability, pharmacokinetics, and safety in mice
    • DOI 10.1016/j.cbi.2005.10.028, PII S0009279705002693
    • Saxena A, Sun W, Luo C, and Doctor BP (2005) Human serum butyrylcholinesterase: In vitro and in vivo stability, pharmacokinetics, and safety in mice. Chem Biol Interact 157-158:199-203. (Pubitemid 41757651)
    • (2005) Chemico-Biological Interactions , vol.157-158 , pp. 199-203
    • Saxena, A.1    Sun, W.2    Luo, C.3    Doctor, B.P.4
  • 32
    • 50049116598 scopus 로고    scopus 로고
    • Developing procedures for the large-scale purification of human serum butyrylcholinesterase
    • Saxena A, Luo C, and Doctor BP (2008) Developing procedures for the large-scale purification of human serum butyrylcholinesterase. Protein Expr Purif 61:191-196.
    • (2008) Protein Expr Purif , vol.61 , pp. 191-196
    • Saxena, A.1    Luo, C.2    Doctor, B.P.3
  • 35
    • 0000605095 scopus 로고
    • Anticholinesterase agents
    • (Gilman AG, Rall TW, Nies AS, and Taylor P eds) Macmillan, New York
    • Taylor P (1990) Anticholinesterase agents, in The Pharmacological Basis of Therapeutics (Gilman AG, Rall TW, Nies AS, and Taylor P eds) pp 131-149, Macmillan, New York.
    • (1990) The Pharmacological Basis of Therapeutics , pp. 131-149
    • Taylor, P.1
  • 36
    • 0033856775 scopus 로고    scopus 로고
    • Viral vectors for gene transfer: A review of their use in the treatment of human diseases
    • Walther W and Stein U (2000) Viral vectors for gene transfer: a review of their use in the treatment of human diseases. Drugs 60:249-271. (Pubitemid 30680387)
    • (2000) Drugs , vol.60 , Issue.2 , pp. 249-271
    • Walther, W.1    Stein, U.2
  • 37
    • 0028484704 scopus 로고
    • MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses
    • DOI 10.1016/1074-7613(94)90074-4
    • Yang Y, Ertl HC, and Wilson JM (1994) MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses. Immunity 1:433-442. (Pubitemid 2134473)
    • (1994) Immunity , vol.1 , Issue.5 , pp. 433-442
    • Yang, Y.1    Ertl, H.C.J.2    Wilson, J.M.3
  • 38
    • 0028937785 scopus 로고
    • Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
    • Yang Y, Li Q, Ertl HC, and Wilson JM (1995) Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J Virol 69:2004-2015.
    • (1995) J Virol , vol.69 , pp. 2004-2015
    • Yang, Y.1    Li, Q.2    Ertl, H.C.3    Wilson, J.M.4


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