Efficacy of antioxidant treatment in the prevention of testicular atrophy in experimental testicular torsion

Journal of Pediatric Surgery

Volumn 44, Issue 9, 2009, Pages 1754-1758

  Yurtçu, Müslim ^a   Abasiyanik, Adnan ^a   Biçer, Şenol ^a   Avunduk, Mustafa Cihat ^a  

^a SELCUK UNIVERSITY   (Turkey)

Author keywords

Ischemia reperfusion damage; Melatonin; Steroid; Testicular torsion

Indexed keywords

ANTIOXIDANT; M 250; MELATONIN; METHYLPREDNISOLONE; PREDNOL L; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG EFFICACY; EXPERIMENTAL RAT; HISTOPATHOLOGY; ISCHEMIA; MALE; NONHUMAN; ORCHIECTOMY; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; TESTIS ATROPHY; TESTIS TORSION; TESTIS WEIGHT;

ANIMALS; ANTIOXIDANTS; ATROPHY; DRUG EVALUATION, PRECLINICAL; MALE; MELATONIN; METHYLPREDNISOLONE; ORCHIECTOMY; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; SPERMATIC CORD TORSION; TESTIS;

EID: 69549108489     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2008.11.043     Document Type: Article

References (33)

1. Barada J.H., Weingarten J.L., and Cromie W.J. Testicular salvage and age-related delay in the presentation of testicular torsion. J Urol 142 (1989) 746-748
2. Filho D.W., Torres M.A., Bordin A.L., et al. Spermatic cord torsion, reactive oxygen and nitrogen species and ischemia-reperfusion injury. Mol Aspects Med 25 (2004) 199-210
3. Yurtcu M., Abasi{dotless}yani{dotless}k A., Avunduk M.C., et al. Effects of melatonin on spermatogenesis and testicular ischemia-reperfusion injury after unilateral testicular torsion-detorsion. J Pediatr Surg 43 (2008) 1873-1878
4. Pablos M.I., Chuang J., Reiter R., et al. Time course of the melatonin-induced increase in glutathione peroxidase activity in chick tissues. Biol Signals 4 (1995) 325-330
5. Sliwinski T, Rozej W, Morawiec-Bajda A, et al. Protective action of melatonin against oxidative DNA damage: chemical inactivation versus base-excision repair. 2007;634(1-2):220-7. [Electronic publication 2007 Aug 9].
6. Maurel D.L., Saad M.M.B., Roch G., et al. Testicular activity is restored by melatonin replacement after suprachiasmatic nucleus lesion or superior cervical ganglionectomy in mink. J Pineal Res 32 (2002) 15-20
7. Soybir G., Topuzlu C., Odabaş Ö., et al. The effects of melatonin on angiogenesis and wound healing. Surg Today 33 (2003) 896-901
8. Jansen N.J., van Oeveren W., van den Broek L., et al. Inhibition by dexamethasone of the reperfusion phenomena in cardiopulmonary bypass. J Thorac Cardiovasc Surg 102 (1991) 515-525
9. Greenstein A., Smith-Harrison L.I., Wakely P.E., et al. The effect of polyethylene glycol-superoxide dismutase administration on histological damage following spermatic cord torsion. J Urol 148 (1992) 639-641
10. Blank M.L., O'Neill P.J., Steigman C.K., et al. Reperfusion injury following testicular torsion and detorsion in prepubertal rats. Urol Res 21 (1993) 389-393
11. Prillaman H.M., and Turner T.T. Rescue of testicular function after acute experimental torsion. J Urol 157 (1997) 340-345
12. Johnsen S.G. Testicular biopsy score count-a method for registration of spermatogenesis in human testes: normal values and results in 352 hypogonadal males. Hormones 1 (1970) 1-24
13. Krarup T. The testis after torsion. Br J Urol 50 (1978) 43-46
14. Turner T.T., and Brown K.J. Spermatic cord torsion: loss of spermatogenesis despite return of blood flow. Biol Reprod 49 (1993) 401-407
15. Janetschek G., Schreckenberg F., Mikuz G., et al. Experimental testicular torsion: effect on endocrine and exocrine function and contralateral testicular histology. Urol Res 16 (1988) 43
16. Jhunjhunwala J.S., Desai A., and Kropp K. Torsion of the spermatic cord: an experimental study. Invest Urol 13 (1976) 18
17. Arap M.A., Vicentini F.C., Cocuzza M., et al. Late hormonal levels, semen parameters, and presence of antisperm antibodies in patients treated for testicular torsion. J Androl 28 (2007) 528-532
18. Akgül T., Ayyi{dotless}ldi{dotless}z A., Nuhoǧlu B., et al. Ginkgo biloba (EGb 761) usage attenuates testicular injury induced by testicular ischemia/reperfusion in rats. Int Urol Nephrol (2007) [Electronic publication ahead of print]
19. Beheshtian A., Salmasi A.H., Payabvash S., et al. Protective effects of sildenafil administration on testicular torsion/detorsion damage in rats. World J Urol (2008) Feb 12 [Electronic publication ahead of print]
20. Kehinde E.O., Anim J.T., Mojiminiyi O.A., et al. Allopurinol provides long-term protection for experimentally induced testicular torsion in a rabbit model. BJU Int 96 1 (2005) 175-180
21. Wei S.M., Yan Z.Z., and Zhou J. Beneficial effect of taurine on testicular ischemia-reperfusion injury in rats. Urology 70 (2007) 1237-1242
22. Avlan D., Erdogan K., Cimen B., et al. The protective effect of selenium on ipsilateral and contralateral testes in testicular reperfusion injury. Pediatr Surg Int 21 (2005) 274-278
23. Abasi{dotless}yani{dotless}k A., and Daǧdönderen L. Beneficial effects of melatonin compared with allopurinol in experimental testicular torsion. J Pediatr Surg 39 (2004) 1238-1241
24. Wirz-Justice A. Melatonin: a new wonder drug?. Schweiz-Rundsch-Med-Prax 85 (1996) 1332-1336
25. Bickerstaff K.I., Sethia K., and Murie J.A. Doppler ultrasonography in the diagnosis of acute scrotal pain. Br J Surg 75 (1988) 238-239
26. Becker E.J., and Turner T.T. Endocrine and exocrine effects of testicular torsion in the prepubertal and adult rat. J Androl 16 (1995) 342-346
27. Laurence D.R., Bennett P.N., and Brown M.J. Clinical pharmacology (1997), Churchill Livingstone, Singapore 599-614
28. Yazawa H., Sasagawa I., Suzuki Y., et al. Glucocorticoid hormone can suppress apoptosis of rat testicular germ cells induced by testicular ischemia. Fertil Steril 75 (2001) 980-985
29. Bozlu M., Coskun B., Cayan S., et al. Inhibition of poly (adenosine diphosphate-ribose) polymerase decreases long-term histologic damage in testicular ischemia-reperfusion injury. Urology 63 4 (2004) 791-795
30. Abes M., Sarihan H., Deger O., et al. The effect of ATP-MgCl2 on prevention of reperfusion injury after testicular torsion. Eur J Pediatr Surg 11 (2001) 255-258
31. Adivarekar P.K., Bhagwat S.S., Raghavan V., et al. Effect of Lomodex-MgSO(4) in the prevention of reperfusion injury following unilateral testicular torsion: an experimental study in rats. Pediatr Surg Int 21 3 (2005) 184-190
32. Anderson J.B., and Williams R.C. The fate of human testes following unilateral torsion of the spermatic cord. Br J Urol 58 (1986) 698
33. Werns S.W., and Lucchesi B.R. Free radicals and ischemic tissue injury. Trends Pharmacol Sci 11 (1990) 161