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Volumn 122, Issue 15, 2009, Pages 2632-2639

Transmembrane segments of the dynamin Msp1p uncouple its functions in the control of mitochondrial morphology and genome maintenance

Author keywords

Mgm1; Mitochondria; Mitochondrial dynamics; Msp1; mtDNA; OPA1

Indexed keywords

DYNAMIN I; MATRIX PEPTIDASE MATURED 1 PROTEIN; MITOCHONDRIAL DNA; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; UNCLASSIFIED DRUG;

EID: 69549096274     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.040139     Document Type: Article
Times cited : (11)

References (52)
  • 4
    • 33644674439 scopus 로고    scopus 로고
    • The organization and inheritance of the mitochondrial genome
    • Chen, X. J. and Butow, R. A. (2005). The organization and inheritance of the mitochondrial genome. Nat. Rev. Genet. 6, 815-825.
    • (2005) Nat. Rev. Genet , vol.6 , pp. 815-825
    • Chen, X.J.1    Butow, R.A.2
  • 11
    • 0034676062 scopus 로고    scopus 로고
    • Gag3p, an outer membrane protein required for fission of mitochondrial tubules
    • Fekkes, P., Shepard, K. A. and Yaffe, M. P. (2000). Gag3p, an outer membrane protein required for fission of mitochondrial tubules. J. Cell Biol. 151, 333-340.
    • (2000) J. Cell Biol , vol.151 , pp. 333-340
    • Fekkes, P.1    Shepard, K.A.2    Yaffe, M.P.3
  • 14
    • 2442421118 scopus 로고    scopus 로고
    • Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria
    • Griparic, L., van der Wel, N. N., Orozco, I. J., Peters, P. J. and van der Bliek, A. M. (2004). Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria. J. Biol. Chem. 279, 18792-18798.
    • (2004) J. Biol. Chem , vol.279 , pp. 18792-18798
    • Griparic, L.1    van der Wel, N.N.2    Orozco, I.J.3    Peters, P.J.4    van der Bliek, A.M.5
  • 15
    • 34548313686 scopus 로고    scopus 로고
    • Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage
    • Griparic, L., Kanazawa, T. and van der Bliek, A. M. (2007). Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage. J. Cell Biol. 178, 757-764.
    • (2007) J. Cell Biol , vol.178 , pp. 757-764
    • Griparic, L.1    Kanazawa, T.2    van der Bliek, A.M.3
  • 17
    • 13844259307 scopus 로고    scopus 로고
    • Msp1p is an intermembrane space dynamin-related protein that mediates mitochondrial fusion in a Dnm1p-dependent manner in S. pombe
    • Guillou, E., Bousquet, C., Daloyau, M., Emorine, L. J. and Belenguer, P. (2005). Msp1p is an intermembrane space dynamin-related protein that mediates mitochondrial fusion in a Dnm1p-dependent manner in S. pombe. FEBS Lett. 579, 1109-1116.
    • (2005) FEBS Lett , vol.579 , pp. 1109-1116
    • Guillou, E.1    Bousquet, C.2    Daloyau, M.3    Emorine, L.J.4    Belenguer, P.5
  • 18
    • 0042526632 scopus 로고    scopus 로고
    • Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA
    • Herlan, M., Vogel, F., Bornhovd, C., Neupert, W. and Reichert, A. S. (2003). Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA. J. Biol. Chem. 278, 27781-27788.
    • (2003) J. Biol. Chem , vol.278 , pp. 27781-27788
    • Herlan, M.1    Vogel, F.2    Bornhovd, C.3    Neupert, W.4    Reichert, A.S.5
  • 19
    • 2142710081 scopus 로고    scopus 로고
    • Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor
    • Herlan, M., Bornhovd, C., Hell, K., Neupert, W. and Reichert, A. S. (2004). Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor. J. Cell Biol. 165, 167-173.
    • (2004) J. Cell Biol , vol.165 , pp. 167-173
    • Herlan, M.1    Bornhovd, C.2    Hell, K.3    Neupert, W.4    Reichert, A.S.5
  • 21
    • 34250204271 scopus 로고    scopus 로고
    • The machines that divide and fuse mitochondria
    • Hoppins, S., Lackner, L. and Nunnari, J. (2007). The machines that divide and fuse mitochondria. Annu. Rev. Biochem. 76, 751-780.
    • (2007) Annu. Rev. Biochem , vol.76 , pp. 751-780
    • Hoppins, S.1    Lackner, L.2    Nunnari, J.3
  • 22
    • 38849151612 scopus 로고    scopus 로고
    • Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: A novel disorder of mtDNA maintenance
    • Hudson, G., Amati-Bonneau, P., Blakely, E. L., Stewart, J. D., He, L., Schaefer, A. M., Griffiths, P. G., Ahlqvist, K., Suomalainen, A., Reynier, P. et al. (2008). Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: a novel disorder of mtDNA maintenance. Brain 131, 329-337.
    • (2008) Brain , vol.131 , pp. 329-337
    • Hudson, G.1    Amati-Bonneau, P.2    Blakely, E.L.3    Stewart, J.D.4    He, L.5    Schaefer, A.M.6    Griffiths, P.G.7    Ahlqvist, K.8    Suomalainen, A.9    Reynier, P.10
  • 23
    • 33746299692 scopus 로고    scopus 로고
    • Regulation of mitochondrial morphology through proteolytic cleavage of OPA1
    • Ishihara, N., Fujita, Y., Oka, T. and Mihara, K. (2006). Regulation of mitochondrial morphology through proteolytic cleavage of OPA1. EMBO J. 25, 2966-2977.
    • (2006) EMBO J , vol.25 , pp. 2966-2977
    • Ishihara, N.1    Fujita, Y.2    Oka, T.3    Mihara, K.4
  • 25
    • 0026544936 scopus 로고
    • Mitochondrial DNA maintenance in yeast requires a protein containing a region related to the GTP-binding domain of dynamin
    • Jones, B. A. and Fangman, W. L. (1992). Mitochondrial DNA maintenance in yeast requires a protein containing a region related to the GTP-binding domain of dynamin. Genes Dev. 6, 380-389.
    • (1992) Genes Dev , vol.6 , pp. 380-389
    • Jones, B.A.1    Fangman, W.L.2
  • 26
    • 4644242944 scopus 로고    scopus 로고
    • Endophilin B1 is required for the maintenance of mitochondrial morphology
    • Karbowski, M., Jeong, S. Y. and Youle, R. J. (2004). Endophilin B1 is required for the maintenance of mitochondrial morphology. J. Cell Biol. 166, 1027-1039.
    • (2004) J. Cell Biol , vol.166 , pp. 1027-1039
    • Karbowski, M.1    Jeong, S.Y.2    Youle, R.J.3
  • 27
    • 33745737928 scopus 로고    scopus 로고
    • Structure and dynamics of the mitochondrial inner membrane cristae
    • Mannella, C. A. (2006). Structure and dynamics of the mitochondrial inner membrane cristae. Biochim. Biophys. Acta 1763, 542-548.
    • (2006) Biochim. Biophys. Acta , vol.1763 , pp. 542-548
    • Mannella, C.A.1
  • 28
    • 0038700756 scopus 로고    scopus 로고
    • Mitochondrial membrane remodelling regulated by a conserved rhomboid protease
    • McQuibban, G. A., Saurya, S. and Freeman, M. (2003). Mitochondrial membrane remodelling regulated by a conserved rhomboid protease. Nature 423, 537-541.
    • (2003) Nature , vol.423 , pp. 537-541
    • McQuibban, G.A.1    Saurya, S.2    Freeman, M.3
  • 29
    • 33749991592 scopus 로고    scopus 로고
    • Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1
    • Meeusen, S., DeVay, R., Block, J., Cassidy-Stone, A., Wayson, S., McCaffery, J. M. and Nunnari, J. (2006). Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1. Cell 127, 383-395.
    • (2006) Cell , vol.127 , pp. 383-395
    • Meeusen, S.1    DeVay, R.2    Block, J.3    Cassidy-Stone, A.4    Wayson, S.5    McCaffery, J.M.6    Nunnari, J.7
  • 31
    • 0026025891 scopus 로고
    • Molecular genetic analysis of fission yeast Schizosaccharomyces pombe
    • ed. C. Gutrie and G. Fink, pp, New York: Academic Press
    • Moreno, S., Klar, A. and Nurse, P. (1991). Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. In Guide To Yeast Genetics and Molecular Biology, vol. 194 (ed. C. Gutrie and G. Fink), pp. 795-826. New York: Academic Press.
    • (1991) Guide To Yeast Genetics and Molecular Biology , vol.194 , pp. 795-826
    • Moreno, S.1    Klar, A.2    Nurse, P.3
  • 32
    • 25444514731 scopus 로고    scopus 로고
    • Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: New implications for Charcot-Marie-Tooth disease
    • Niemann, A., Ruegg, M., La Padula, V., Schenone, A. and Suter, U. (2005). Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease. J. Cell Biol. 170, 1067-1078.
    • (2005) J. Cell Biol , vol.170 , pp. 1067-1078
    • Niemann, A.1    Ruegg, M.2    La Padula, V.3    Schenone, A.4    Suter, U.5
  • 33
    • 27544466847 scopus 로고    scopus 로고
    • Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes
    • Okamoto, K. and Shaw, J. M. (2005). Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes. Annu. Rev. Genet. 39, 503-536.
    • (2005) Annu. Rev. Genet , vol.39 , pp. 503-536
    • Okamoto, K.1    Shaw, J.M.2
  • 35
    • 0037424239 scopus 로고    scopus 로고
    • Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
    • Olichon, A., Baricault, L., Gas, N., Guillou, E., Valette, A., Belenguer, P. and Lenaers, G. (2003). Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J. Biol. Chem. 278, 7743-7746.
    • (2003) J. Biol. Chem , vol.278 , pp. 7743-7746
    • Olichon, A.1    Baricault, L.2    Gas, N.3    Guillou, E.4    Valette, A.5    Belenguer, P.6    Lenaers, G.7
  • 37
    • 33947434544 scopus 로고    scopus 로고
    • OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis
    • Olichon, A., Elachouri, G., Baricault, L., Delettre, C., Belenguer, P. and Lenaers, G. (2007). OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis. Cell Death Differ. 14, 682-692.
    • (2007) Cell Death Differ , vol.14 , pp. 682-692
    • Olichon, A.1    Elachouri, G.2    Baricault, L.3    Delettre, C.4    Belenguer, P.5    Lenaers, G.6
  • 39
    • 0032578769 scopus 로고    scopus 로고
    • Identification of a fission yeast dynamin-related protein involved in mitochondrial DNA maintenance
    • Pelloquin, L., Belenguer, P., Menon, Y. and Ducommun, B. (1998). Identification of a fission yeast dynamin-related protein involved in mitochondrial DNA maintenance. Biochem. Biophys. Res. Commun. 251, 720-726.
    • (1998) Biochem. Biophys. Res. Commun , vol.251 , pp. 720-726
    • Pelloquin, L.1    Belenguer, P.2    Menon, Y.3    Ducommun, B.4
  • 40
    • 0033490111 scopus 로고    scopus 로고
    • Fission yeast Msp1 is a mitochondrial dynamin related protein
    • Pelloquin, L., Belenguer, P., Menon, Y., Gas, N. and Ducommun, B. (1999). Fission yeast Msp1 is a mitochondrial dynamin related protein. J. Cell Sci. 112, 4151-4161.
    • (1999) J. Cell Sci , vol.112 , pp. 4151-4161
    • Pelloquin, L.1    Belenguer, P.2    Menon, Y.3    Gas, N.4    Ducommun, B.5
  • 41
    • 0742288598 scopus 로고    scopus 로고
    • The dynamin superfamily: Universal membrane tubulation and fission molecules?
    • Praefcke, G. J. and McMahon, H. T. (2004). The dynamin superfamily: universal membrane tubulation and fission molecules? Nat. Rev. Mol. Cell Biol. 5, 133-147.
    • (2004) Nat. Rev. Mol. Cell Biol , vol.5 , pp. 133-147
    • Praefcke, G.J.1    McMahon, H.T.2
  • 42
    • 0034711953 scopus 로고    scopus 로고
    • The GxxxG motif: A framework for transmembrane helix-helix association
    • Russ, W. P. and Engelman, D. M. (2000). The GxxxG motif: a framework for transmembrane helix-helix association. J. Mol. Biol. 296, 911-919.
    • (2000) J. Mol. Biol , vol.296 , pp. 911-919
    • Russ, W.P.1    Engelman, D.M.2
  • 43
    • 0037427529 scopus 로고    scopus 로고
    • Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria
    • Satoh, M., Hamamoto, T., Seo, N., Kagawa, Y. and Endo, H. (2003). Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria. Biochem. Biophys. Res. Commun. 300, 482-493.
    • (2003) Biochem. Biophys. Res. Commun , vol.300 , pp. 482-493
    • Satoh, M.1    Hamamoto, T.2    Seo, N.3    Kagawa, Y.4    Endo, H.5
  • 44
    • 0035911963 scopus 로고    scopus 로고
    • UGO1 encodes an outer membrane protein required for mitochondrial fusion
    • Sesaki, H. and Jensen, R. E. (2001). UGO1 encodes an outer membrane protein required for mitochondrial fusion. J. Cell Biol. 152, 1123-1134.
    • (2001) J. Cell Biol , vol.152 , pp. 1123-1134
    • Sesaki, H.1    Jensen, R.E.2
  • 45
    • 0043095416 scopus 로고    scopus 로고
    • Cells lacking Pcp1p/Ugo2p, a rhomboid-like protease required for Mgm1p processing, lose mtDNA and mitochondrial structure in a Dnm1p-dependent manner, but remain competent for mitochondrial fusion
    • Sesaki, H., Southard, S. M., Hobbs, A. E. and Jensen, R. E. (2003a). Cells lacking Pcp1p/Ugo2p, a rhomboid-like protease required for Mgm1p processing, lose mtDNA and mitochondrial structure in a Dnm1p-dependent manner, but remain competent for mitochondrial fusion. Biochem. Biophys. Res. Commun. 308, 276-283.
    • (2003) Biochem. Biophys. Res. Commun , vol.308 , pp. 276-283
    • Sesaki, H.1    Southard, S.M.2    Hobbs, A.E.3    Jensen, R.E.4
  • 46
    • 0038376024 scopus 로고    scopus 로고
    • Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane
    • Sesaki, H., Southard, S. M., Yaffe, M. P. and Jensen, R. E. (2003b). Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane. Mol. Biol. Cell 14, 2342-2356.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 2342-2356
    • Sesaki, H.1    Southard, S.M.2    Yaffe, M.P.3    Jensen, R.E.4
  • 47
    • 27744511577 scopus 로고    scopus 로고
    • Multistep and multimode cortical anchoring of tea1p at cell tips in fission yeast
    • Snaith, H. A., Samejima, I. and Sawin, K. E. (2005). Multistep and multimode cortical anchoring of tea1p at cell tips in fission yeast. EMBO J. 24, 3690-3699.
    • (2005) EMBO J , vol.24 , pp. 3690-3699
    • Snaith, H.A.1    Samejima, I.2    Sawin, K.E.3
  • 48
    • 34548313688 scopus 로고    scopus 로고
    • OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L
    • Song, Z., Chen, H., Fiket, M., Alexander, C. and Chan, D. C. (2007). OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L. J. Cell Biol. 178, 749-755.
    • (2007) J. Cell Biol , vol.178 , pp. 749-755
    • Song, Z.1    Chen, H.2    Fiket, M.3    Alexander, C.4    Chan, D.C.5
  • 49
    • 23844539004 scopus 로고    scopus 로고
    • The mitochondrial protein MTP18 contributes to mitochondrial fission in mammalian cells
    • Tondera, D., Czauderna, F., Paulick, K., Schwarzer, R., Kaufmann, J. and Santel, A. (2005). The mitochondrial protein MTP18 contributes to mitochondrial fission in mammalian cells. J. Cell Sci. 118, 3049-3059.
    • (2005) J. Cell Sci , vol.118 , pp. 3049-3059
    • Tondera, D.1    Czauderna, F.2    Paulick, K.3    Schwarzer, R.4    Kaufmann, J.5    Santel, A.6
  • 50
    • 0034676095 scopus 로고    scopus 로고
    • The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria
    • Wong, E. D., Wagner, J. A., Gorsich, S. W., McCaffery, J. M., Shaw, J. M. and Nunnari, J. (2000). The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria. J. Cell Biol. 151, 341-352.
    • (2000) J. Cell Biol , vol.151 , pp. 341-352
    • Wong, E.D.1    Wagner, J.A.2    Gorsich, S.W.3    McCaffery, J.M.4    Shaw, J.M.5    Nunnari, J.6
  • 51
    • 0037415638 scopus 로고    scopus 로고
    • The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion
    • Wong, E. D., Wagner, J. A., Scott, S. V., Okreglak, V., Holewinske, T. J., Cassidy-Stone, A. and Nunnari, J. (2003). The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion. J. Cell Biol. 160, 303-311.
    • (2003) J. Cell Biol , vol.160 , pp. 303-311
    • Wong, E.D.1    Wagner, J.A.2    Scott, S.V.3    Okreglak, V.4    Holewinske, T.J.5    Cassidy-Stone, A.6    Nunnari, J.7


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