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Volumn 49, Issue 9, 2009, Pages 1010-1011

Model-based evaluation of QTc interval risk: An increasing emphasis on early decision making

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR RISK; EDITORIAL; ELECTROCARDIOGRAM; HEART RATE; MEDICAL DECISION MAKING; PHARMACOKINETICS; QT INTERVAL;

EID: 69549095762     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270009344086     Document Type: Editorial
Times cited : (4)

References (5)
  • 1
    • 70350422753 scopus 로고    scopus 로고
    • Is a thorough QTC study necessary? the role of modeling and simulation in evaluating the QTc prolongation potential of drugs
    • Rohatagi S., Carrothers TJ, Kuwabara-Wagg J., Khariton T. Is a thorough QTC study necessary? The role of modeling and simulation in evaluating the QTc prolongation potential of drugs. J Clin Pharmacol. In press.
    • J Clin Pharmacol
    • Rohatagi, S.1    Carrothers, T.J.2    Kuwabara-Wagg, J.3    Khariton, T.4
  • 3
    • 51849093126 scopus 로고    scopus 로고
    • Near-thorough QT study as part of a first-in-man study
    • Malik M., Hnatkova K., Ford J., Madge D. Near-thorough QT study as part of a first-in-man study. J Clin Pharmacol. 2008 ; 48: 1146-1157.
    • (2008) J Clin Pharmacol , vol.48 , pp. 1146-1157
    • Malik, M.1    Hnatkova, K.2    Ford, J.3    Madge, D.4
  • 4
    • 50249105403 scopus 로고    scopus 로고
    • Early clinical development: Evaluation of drug-induced torsades de pointes risk
    • Vik T., Pollard C., Sager P. Early clinical development: evaluation of drug-induced torsades de pointes risk. Pharmacol Ther. 2008 ; 119: 210-214.
    • (2008) Pharmacol Ther , vol.119 , pp. 210-214
    • Vik, T.1    Pollard, C.2    Sager, P.3
  • 5
    • 68749109281 scopus 로고    scopus 로고
    • Comparison of electrocardiographic analysis for risk of QT interval prolongation using safety pharmacology and toxicological studies
    • Guth BD, Bass AS, Briscoe R., et al. Comparison of electrocardiographic analysis for risk of QT interval prolongation using safety pharmacology and toxicological studies. J Pharmacol Toxicol Methods. 2009 May 24. [Epub ahead of print]
    • (2009) J Pharmacol Toxicol Methods
    • Guth, B.D.1    Bass, A.S.2    Briscoe, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.