Blood phenylalanine concentrations in patients with PAH-deficient hyperphenylalaninaemia off diet without and with three different single oral doses of tetrahydrobiopterin: Assessing responsiveness in a model of statistical process control

Journal of Inherited Metabolic Disease

Volumn 32, Issue 4, 2009, Pages 514-522

  Lindner, Martin ^a   Gramer, G ^a   Garbade, S F ^a   Burgard, P ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PHENYLALANINE; PHENYLALANINE 4 MONOOXYGENASE; PTERIN; TETRAHYDROBIOPTERIN;

ADULT; AMINO ACID BLOOD LEVEL; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET RESTRICTION; DIET SUPPLEMENTATION; DRUG RESPONSE; FEMALE; GENOTYPE; HUMAN; HYPERPHENYLALANINEMIA; LOADING TEST; MALE; NEWBORN SCREENING; PHENOTYPE; PHENYLKETONURIA; PROCESS CONTROL; PROTEIN DIET; PROTEIN INTAKE; SINGLE DRUG DOSE; UNSPECIFIED SIDE EFFECT;

ADMINISTRATION, ORAL; ADULT; BIOPTERIN; CROSS-OVER STUDIES; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MODELS, STATISTICAL; PHENYLALANINE; PHENYLALANINE HYDROXYLASE; PHENYLKETONURIAS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 69449106872     PISSN: 01418955     EISSN: 15732665     Source Type: Journal    
DOI: 10.1007/s10545-009-1070-7     Document Type: Article

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