The malarial parasite Plasmodium falciparum imports the human protein peroxiredoxin 2 for peroxide detoxification

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 32, 2009, Pages 13323-13328

  Koncarevic, Sasa ^a,b   Rohrbach, Petra ^c,d   Deponte, Marcel ^a,e   Krohne, Georg ^f   Prieto, Judith Helena ^g   Yates III, John ^g   Rahlfs, Stefan ^a   Becker, Katja ^a  

^a Interdisciplinary Research Center   (Germany)

^b Proteome Sciences R and D GmbH and Co KG   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d MCGILL UNIVERSITY   (Canada)

^e UNIVERSITY OF MUNICH   (Germany)

^f UNIVERSITY OF WÜRZBURG   (Germany)

^g SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Antioxidant defense; Maurer's clefts; Protein import; Redox metabolism; Thioredoxin

Indexed keywords

CHLOROQUINE; PEROXIDE; PEROXIREDOXIN 2; THIOREDOXIN 1; THIOREDOXIN PEROXIDASE;

ARTICLE; CELL FRACTIONATION; CELL ORGANELLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; DETOXIFICATION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SUBSTRATE; IMMUNOGOLD ELECTRON MICROSCOPY; MOLECULAR INTERACTION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; STEADY STATE; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ANIMALS; CARRIER PROTEINS; CELL EXTRACTS; CHLOROQUINE; CYTOSOL; ERYTHROCYTES; FLUORESCENT ANTIBODY TECHNIQUE; GREEN FLUORESCENT PROTEINS; HEMOGLOBINS; HUMANS; KINETICS; MALARIA, FALCIPARUM; MEMBRANE PROTEINS; METABOLIC DETOXICATION, DRUG; PEROXIDES; PEROXIREDOXINS; PLASMODIUM FALCIPARUM; PROTEIN TRANSPORT; PROTOZOAN PROTEINS; VACUOLES;

PLASMODIUM FALCIPARUM;

EID: 69449106780     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0905387106     Document Type: Article

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