Second-site mutations in Borna disease virus overexpressing viral accessory protein X

Journal of General Virology

Volumn 90, Issue 8, 2009, Pages 1932-1936

  Poenisch, Marion ^a   Wille, Sandra ^a   Schneider, Urs ^a   Staeheli, Peter ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS PROTEIN X;

ANIMAL TISSUE; ARTICLE; BORNA DISEASE VIRUS; CONTROLLED STUDY; GENE DUPLICATION; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; NONHUMAN; PRIORITY JOURNAL; RAT; VIRUS GENE; ANIMAL; BIOSYNTHESIS; BRAIN; DNA SEQUENCE; GENE DOSAGE; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENETICS; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; VIROLOGY; VIRUS REPLICATION;

BORNA DISEASE VIRUS; RATTUS;

ANIMALS; BORNA DISEASE VIRUS; BRAIN; DNA MUTATIONAL ANALYSIS; GENE DOSAGE; GENE EXPRESSION REGULATION, VIRAL; GENE KNOCKOUT TECHNIQUES; MUTATION, MISSENSE; RATS; SEQUENCE ANALYSIS, DNA; VIRAL REGULATORY AND ACCESSORY PROTEINS; VIRUS REPLICATION;

EID: 69449105172     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.011841-0     Document Type: Article

References (10)

1. Martin, A., Staeheli, P. & Schneider, U. (2006). RNA polymerase II-controlled expression of antigenomic RNA enhances the rescue efficacies of two different members of the Mononegavirales independently of the site of viral genome replication. J Virol 80, 5708-5715.
2. Poenisch, M., Unterstab, G., Wolff, T., Staeheli, P. & Schneider, U. (2004). The X protein of Borna disease virus regulates viral polymerase activity through interaction with the P protein. J Gen Virol 85, 1895-1898.
3. Poenisch, M., Wille, S., Ackermann, A., Staeheli, P. & Schneider, U. (2007). The X protein of Borna disease virus serves essential functions in the viral multiplication cycle. J Virol 81, 7297-7299.
4. Poenisch, M., Staeheli, P. & Schneider, U. (2008a). Viral accessory protein X stimulates the assembly of functional Borna disease virus polymerase complexes. J Gen Virol 89, 1442-1445.
5. Poenisch, M., Wille, S., Staeheli, P. & Schneider, U. (2008b). Polymerase read-through at the first transcription termination site contributes to regulation of Borna disease virus gene expression. J Virol 82, 9537-9545.
6. Poenisch, M., Burger, N., Staeheli, P., Bauer, G. & Schneider, U. (2009). Protein X of Borna disease virus inhibits apoptosis and promotes viral persistence in the CNS of newborn-infected rats. J Virol 83, 4297-4307.
7. Schneider, U., Naegele, M., Staeheli, P. & Schwemmle, M. (2003). Active Borna disease virus polymerase complex requires a distinct nucleoprotein-to-phosphoprotein ratio but no viral X protein. J Virol 77, 11781-11789.
8. Schneider, U., Ackermann, A. & Staeheli, P. (2007). A Borna disease virus vector for expression of foreign genes in neurons of rodents. J Virol 81, 7293-7296.
9. Schwardt, M., Mayer, D., Frank, R., Schneider, U., Eickmann, M., Planz, O., Wolff, T. & Schwemmle, M. (2005). The negative regulator of Borna disease virus polymerase is a non-structural protein. J Gen Virol 86, 3163-3169.
10. Wolff, T., Pfleger, R., Wehner, T., Reinhardt, J. & Richt, J. A. (2000). A short leucine-rich sequence in the Borna disease virus p10 protein mediates association with the viral phospho- and nucleoproteins. J Gen Virol 81, 939-947.