Mathematical modeling of the circadian rhythm of key neuroendocrine-immune system players in rheumatoid arthritis: A systems biology approach

Arthritis and Rheumatism

Volumn 60, Issue 9, 2009, Pages 2585-2594

  Meyer Hermann, Michael ^a   Figge, Marc Thilo ^a   Straub, Rainer H ^b  

^a FRANKFURT INSTITUTE FOR ADVANCED STUDIES   (Germany)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; HYDROCORTISONE; NORADRENALIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ANTIBODY;

ARTICLE; CHRONOTHERAPY; CIRCADIAN RHYTHM; CLINICAL ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; EVENING DOSAGE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; IMMUNE SYSTEM; IMMUNOMODULATION; MATHEMATICAL MODEL; MOLECULAR INTERACTION; MORNING DOSAGE; NEUROENDOCRINE SYSTEM; NONLINEAR SYSTEM; NORADRENALIN BLOOD LEVEL; NORADRENALIN RELEASE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RHEUMATOID ARTHRITIS; SIMULATION; TREATMENT DURATION; TREATMENT RESPONSE;

ARTHRITIS, RHEUMATOID; CHOLESTEROL; CIRCADIAN RHYTHM; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; IMMUNE SYSTEM; MODELS, THEORETICAL; NEUROSECRETORY SYSTEMS; NOREPINEPHRINE; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 69449102902     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24797     Document Type: Article

References (23)

1. Straub RH, Cutolo M. Circadian rhythms in rheumatoid arthritis: implications for pathophysiology and therapeutic management [review]. Arthritis Rheum 2007;56:399-408. (Pubitemid 46271966)
2. Arvidson NG, Gudbjornsson B, Larsson A, Hallgren R. The timing of glucocorticoid administration in rheumatoid arthritis. Ann Rheum Dis 1997;56:27-31. (Pubitemid 27060569)
3. Buttgereit F, Doering G, Schaeffler A, Witte S, Sierakowski S, Gromnica-Ihle E, et al. Efficacy of modified-release versus standard prednisone to reduce duration of morning stiffness of the joints in rheumatoid arthritis (CAPRA-1): a double-blind, randomised controlled trial. Lancet 2008;371:205-214
4. Gibson EM, Williams WP III, Kriegsfeld LJ. Aging in the circadian system: considerations for health, disease prevention and longevity. Exp Gerontol 2009;44:51-56
5. Jit M, Henderson B, Stevens M, Seymour RM. TNF-α neutralization in cytokine-driven diseases: a mathematical model to account for therapeutic success in rheumatoid arthritis but therapeutic failure in systemic inflammatory response syndrome [published erratum appears in Rheumatology (Oxford) 2005;44:569]. Rheumatology (Oxford) 2005;44:323-331
6. Chakraborty A, Krzyzanski W, Jusko WJ. Mathematical modeling of circadian cortisol concentrations using indirect response models: comparison of several methods. J Pharmacokinet Biopharm 1999;27:23-43. (Pubitemid 29382286)
7. Bennett MR, Farnell L, Gibson WG, Blair D. A quantitative description of the diffusion of noradrenaline in the media of blood vessels following its release from sympathetic varicosities. J Theor Biol 2004;226:359-372 (Pubitemid 37476183)
8. Bornholdt S. Less is more in modeling large genetic networks. Science 2005;310:49-50. (Pubitemid 41507947)
9. MacGregor AG, Wayne EJ. Fluorescein test of circulation time in peripheral vascular disease. Br Heart J 1951;13:80-88
10. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-324
11. Koenigsberg HW, Teicher MH, Mitropoulou V, Navalta C, New AS, Trestman R, et al. 24-h monitoring of plasma norepinephrine, MHPG, cortisol, growth hormone and prolactin in depression. J Psychiatr Res 2004;38:503-511 (Pubitemid 39221758)
12. Saxne T, Palladino MA Jr, Heinegard D, Talal N, Wollheim FA. Detection of tumor necrosis factor α but not tumor necrosis factor β in rheumatoid arthritis synovial fluid and serum. Arthritis Rheum 1988;31:1041-1045 (Pubitemid 18207972)
13. Keenan DM, Roelfsema F, Veldhuis JD. Endogenous ACTH concentration- dependent drive of pulsatile cortisol secretion in the human. Am J Physiol Endorinol Metab 2004;287:E652-61. (Pubitemid 39237893)
14. Jelic S, Cupic Z, Kolar-Anic L. Mathematical modeling of the hypothalamic-pituitary-adrenal system activity. Math Biosci 2005;197:173-187 (Pubitemid 41400127)
15. Bairagi N, Chatterjee S, Chattopadhyay J. Variability in the secretion of corticotropin-releasing hormone, adrenocorticotropic hormone and cortisol and understandability of the hypothalamic-pituitary-adrenal axis dynamics - a mathematical study based on clinical evidence. Math Med Biol 2008;25:37-63.
16. Perry MG, Kirwan JR, Jessop DS, Hunt LP. Overnight variations in cortisol, interleukin 6, tumour necrosis factor α and other cytokines in people with rheumatoid arthritis. Ann Rheum Dis 2009;68:63-68
17. Warren RS, Starnes HF Jr, Gabrilove JL, Oettgen HF, Brennan MF. The acute metabolic effects of tumor necrosis factor administration in humans. Arch Surg 1987;122:1396-1400 (Pubitemid 18058287)
18. Straub RH, Harle P, Sarzi-Puttini P, Cutolo M. Tumor necrosis factor-neutralizing therapies improve altered hormone axes: an alternative mode of antiinflammatory action [review]. Arthritis Rheum 2006;54:2039-2046 (Pubitemid 44051059)
19. Straub RH, Gunzler C, Miller LE, Cutolo M, Scholmerich J, Schill S. Antiinflammatory cooperativity of corticosteroids and norepinephrine in rheumatoid arthritis synovial tissue in vivo and in vitro. FASEB J 2002;16:993-1000. (Pubitemid 34753505)
20. Raap T, Justen HP, Miller LE, Cutolo M, Scholmerich J, Straub RH. Neurotransmitter modulation of interleukin 6 (IL-6) and IL-8 secretion of synovial fibroblasts in patients with rheumatoid arthritis compared to osteoarthritis. J Rheumatol 2000;27:2558-2565 (Pubitemid 30847928)
21. Wahle M, Krause A, Ulrichs T, Jonas D, von Wichert P, Burmester GR, et al. Disease activity related catecholamine response of lymphocytes from patients with rheumatoid arthritis. Ann N Y Acad Sci 1999;876:287-296 (Pubitemid 29352138)
22. Baerwald CG, Laufenberg M, Specht T, von Wichert P, Burmester GR, Krause A. Impaired sympathetic influence on the immune response in patients with rheumatoid arthritis due to lymphocyte subset-specific modulation of β2-adrenergic receptors. Br J Rheumatol 1997;36:1262-1269 (Pubitemid 127719710)
23. Weidler C, Holzer C, Harbuz M, Hofbauer R, Angele P, Scholmerich J, et al. Low density of sympathetic nerve fibres and increased density of brain derived neurotrophic factor positive cells in RA synovium. Ann Rheum Dis 2005;64:13-20. (Pubitemid 40075268)