Long-term results of topical mitomycin c 0.02% for primary and recurrent conjunctival-corneal intraepithelial neoplasia

Ophthalmic Plastic and Reconstructive Surgery

Volumn 25, Issue 4, 2009, Pages 296-299

  Ballalai, Priscilla L ^a,b   Erwenne, Clelia M ^a   Martins, Maria Cristina ^a   Lowen, Marcia S ^a   Barros, Jeison N ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b Praça Dr João Mendes ^*  (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

MITOMYCIN C; ANTINEOPLASTIC ANTIBIOTIC; EYE DROPS; MITOMYCIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONJUNCTIVA TUMOR; CONJUNCTIVAL CORNEAL INTRAEPITHELIAL NEOPLASIA; CONJUNCTIVAL CORNEAL INTRAEPITHELIAL NEOPLASIA (; CONTROLLED STUDY; CORNEA EROSION; CORNEA TUMOR; DRUG EFFICACY; FEMALE; HUMAN; MALE; MULTIPLE CYCLE TREATMENT; PRIORITY JOURNAL; SLIT LAMP; TREATMENT DURATION; TREATMENT RESPONSE; TUMOR RECURRENCE; TUMOR REGRESSION; VISUAL ACUITY; BIOPSY; CARCINOMA IN SITU; COMPARATIVE STUDY; CORNEA DISEASE; DOSE RESPONSE; EYE TUMOR; FOLLOW UP; MIDDLE AGED; PATHOLOGY; PROSPECTIVE STUDY; TIME; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; ANTIBIOTICS, ANTINEOPLASTIC; BIOPSY; CARCINOMA IN SITU; CONJUNCTIVAL NEOPLASMS; CORNEAL DISEASES; DOSE-RESPONSE RELATIONSHIP, DRUG; EYE NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MITOMYCIN; NEOPLASM RECURRENCE, LOCAL; OPHTHALMIC SOLUTIONS; PROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME;

EID: 69449102677     PISSN: 07409303     EISSN: None     Source Type: Journal    
DOI: 10.1097/IOP.0b013e3181ac4c39     Document Type: Article

References (26)

1. Fraunfelder FT, Wingfield D. Management of intraepithelial conjunctival tumors and squamous cell carcinomas. Am J Ophthalmol 1983;95:359-63.
2. Erie JC, Campbell RJ, Liesegang TJ. Conjunctival and corneal intraepithelial and invasive neoplasia. Ophthalmology 1986;93:176-83.
3. Frucht-Pery J, Rozenman Y. Mitomycin C therapy for corneal intraepithelial neoplasia. Am J Ophthalmol 1994;117:164-8.
4. Frucht-Pery J, Sugar J, Baum J, et al. Mitomycin C treatment for conjunctival-corneal intraepithelial neoplasia: a multicenter experience. Ophthalmology 1997;104:2085-93.
5. Haas K, Ben-Dor D, Levartovsky S. Treatment of conjunctival corneal intraepithelial neoplasia with topical mitomycin C. Arch Ophthalmol 1999;117:544-5.
6. Rozenman Y, Frucht-Pery J. Treatment of conjunctival intraepithelial neoplasia with topical drops of mitomycin C. Cornea 2000;19:1-6.
7. Daniell M, Maini R, Tole D. Use of mitomycin C in the treatment of corneal conjunctival intraepithelial neoplasia. Clin Exp Ophthalmol 2002;30:94-8.
8. Ramos-Loṕez JF, Martinez-Costa Peŕez R, Cisneros Lanuza AL, et al. [Treatment of conjunctival intraepithelial neoplasia with topical mitomycin C 0.02%]. Arch Soc Esp Oftalmol 2004;79:375-8.
9. Yeatts RP, Ford JG, Stanton CA, Reed JW. Topical 5-fluorouracil in treating epithelial neoplasia of the conjunctiva and cornea. Ophthalmology 1995;102:1338-44.
10. Maskin SL. Regression of limbal epithelial dysplasia with topical interferon. Arch Ophthalmol 1994;112:1145-6.
11. Crooke ST, Bradner WT. Mitomycin C: a review. Cancer Treat Rev 1976;3:121-39.
12. Chabner BA, Allegra CJ, Curt GA, Calabresi P. Antineoplastic agents. In: Gilman AG, ed. Goodman and Gilman's: The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996:1268-9.
13. Wilson MW, Hungerford JL, George SM, Madreperla SA. Topical mitomycin C for the treatment of conjunctival and corneal epithelial dysplasia and neoplasia. Am J Ophthalmol 1997;124:303-11.
14. Dudney BW, Malecha MA. Limbal stem cell deficiency following topical mitomycin C treatment of conjunctival-corneal intraepithelial neoplasia. Am J Ophthalmol 2004;137:950-1.
15. Khong JJ, Muecke J. Complications of mitomycin C therapy in 100 eyes with ocular surface neoplasia. Br J Ophthalmol 2006;90:819-22.
16. Finger PT, Czechonska G, Liarikos S. Topical mitomycin C chemotherapy for conjunctival melanoma and PAM with atypia. Br J Ophthalmol 1998;82:476-9.
17. Demirci H, McCormick SA, Finger PT. Topical mitomycin chemotherapy for conjunctival malignant melanoma and primary acquired melanosis with atypia: clinical experience with histopathologic observations. Arch Ophthalmol 2000;118:885-91.
18. Sacu S, Seǵur-Eltz N, Horvat R, et al. Intumescent cataract after topical mitomycin-C for conjunctival malignant melanoma. Am J Ophthalmol 2003;136:375-7.
19. Tabin G, Levin S, Snibson G, et al. Late recurrences and the necessity for long-term follow-up in corneal and conjunctival intraepithelial neoplasia. Ophthalmology 1997;104:485-92.
20. Neves RA, Nose W, Belfort R Jr. In vivo stain in the diagnosis of neoplastic and displastic lesions of the conjunctiva. Arq Bras Oftalmol 1993;56:308-14.
21. Nolan GR, Hirst LW, Wright RG, Bancroft BJ. Application of impression cytology to the diagnosis of conjunctival neoplasms. Diagn Cytopathol 1994;11:246-9.
22. Tole DM, McKelvie PA, Daniell M. Reliability of impression cytology for the diagnosis of ocular surface squamous neoplasia employing the Biopore membrane. Br J Ophthalmol 2001;85:154-8.
23. McKelvie PA, Daniell M. Impression cytology following mitomycin C therapy for ocular surface squamous neoplasia. Br J Ophthalmol 2001;85:1115-9.
24. Rosner M, Hadar I, Rosen N. Successful treatment with mitomycin C eye drops for conjunctival diffuse intraepithelial neoplasia with sebaceous features. Ophthal Plast Reconstr Surg 2003;19:477-9.
25. Heigle TJ, Stulting RD, Palay DA. Treatment of recurrent conjunctival epithelial neoplasia with topical mitomycin C. Am J Ophthalmol 1997;123:397-9.
26. Salomão DR, Mathers WD, Sutphin JE, et al. Cytological changes in the conjunctiva mimicking malignancy after topical mitomycin C chemotherapy. Ophthalmology 1999;106:1756-60; discussion 1761.