Risk of suicidal behaviour in adults taking antidepressants

BMJ (Online)

Volumn 339, Issue 7718, 2009, Pages 411-

  Geddes, John Richard ^a   Barbui, Corrado ^b   Cipriani, Andrea ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF VERONA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; CITALOPRAM; ESCITALOPRAM; SERTRALINE;

AGE DISTRIBUTION; CLINICAL TRIAL; DEPRESSION; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; EDITORIAL; HUMAN; MAJOR DEPRESSION; MENTAL PATIENT; METHODOLOGY; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SUICIDAL BEHAVIOR; SUICIDAL IDEATION; SUICIDE;

ADULT; ANTIDEPRESSIVE AGENTS; DEPRESSIVE DISORDER; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK FACTORS; SUICIDE;

EID: 69449102544     PISSN: None     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.b3066     Document Type: Editorial

References (12)

1. Stone MB, Laughren T, Jones ML, Levenson M, Holland PC, Hughes A, et al. Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration. BMJ 2009;339:b2880.[Abstract/Free Full Text]
2. Laughren TP. Briefing document for December 13 meeting of Psychopharmacologic Drugs Advisory Committee. 2006. www.fda.gov/ohrms/dockets/ ac/06/briefing/2006-4272b1-01-fda.pdf.
3. Friedman RA, Leon AC. Expanding the black box - depression, antidepressants, and the risk of suicide. N Engl J Med 2007;356:2343-2346[Free Full Text]
4. Kuehn BM. FDA panel seeks to balance risks in warnings for antidepressants. JAMA 2007;297:573-574[Free Full Text]
5. Barbui C, Cipriani A, Geddes JR. Antidepressants and suicide symptoms: compelling new insights from the FDA's analysis of individual patient level data. Evid Based Ment Health 2008;11:34-35[Free Full Text]
6. Leon AC. The revised warning for antidepressants and suicidality: unveiling the black box of statistical analyses. Am J Psychiatry 2007;164:1786-1789[Free Full Text]
7. Gunnell D, Saperia J, Ashby D. Selective serotonin reuptake inhibitors (SSRIs) and suicide in adults: meta-analysis of drug company data from placebo controlled, randomised controlled trials submitted to the MHRA's safety review. BMJ 2005;330:385.[Abstract/Free Full Text] (Pubitemid 40288822)
8. Fergusson D, Doucette S, Glass KC, Shapiro S, Healy D, Hebert P, et al. Association between suicide attempts and selective serotonin reuptake inhibitors: systematic review of randomised controlled trials. BMJ 2005;330:396.[Abstract/Free Full Text]
9. Cipriani A, Barbui C, Geddes JR. Suicide, depression, and antidepressants. BMJ 2005;330:373-374[Free Full Text]
10. Vitry A, Lexchin J, Sasich L, Dupin-Spriet T, Reed T, Bertele V, et al. Provision of information on regulatory authorities' websites. Intern Med J 2008;38:559-567[CrossRef][Web of Science][Medline]
11. Hamburg MA, Sharfstein JM. The FDA as a public health agency. N Engl J Med 2009;360:2493-2495[Free Full Text]
12. Cipriani A, Furukawa TA, Salanti G, Geddes JR, Higgins JP, Churchill R, et al. Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis. Lancet 2009;373:746-758[CrossRef][Web of Science][Medline]