Leishmania donovani trypanothione reductase: Role of urea and guanidine hydrochloride in modulation of functional and structural properties

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1794, Issue 10, 2009, Pages 1474-1484

  Rai, Smita ^a   Dwivedi, Upendra Nath ^b   Goyal, Neena ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b UNIVERSITY OF LUCKNOW   (India)

Author keywords

CD; Fluorescence; Intermediate; Leishmania donovani; Molten globule; Trypanothione reductase; Unfolding

Indexed keywords

GUANIDINE; TRYPANOTHIONE REDUCTASE; UREA;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CROSS LINKING; DENATURATION; DISSOCIATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME REACTIVATION; ION TRANSPORT; LEISHMANIA DONOVANI; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN STRUCTURE;

ANIMALS; CIRCULAR DICHROISM; DIMERIZATION; ENZYME STABILITY; FLAVIN-ADENINE DINUCLEOTIDE; GUANIDINE; LEISHMANIA DONOVANI; MODELS, MOLECULAR; NADH, NADPH OXIDOREDUCTASES; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY; SULFHYDRYL COMPOUNDS; THERMODYNAMICS; TRYPTOPHAN; UREA;

KINETOPLASTIDA; LEISHMANIA DONOVANI; TRYPANOSOMA;

EID: 69449093525     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2009.06.017     Document Type: Article

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