메뉴 건너뛰기




Volumn 32, Issue 1, 2009, Pages 1-8

Different inhibition of acetylcholinesterase in selected parts of the rat brain following intoxication with VX and Russian VX

Author keywords

Acetylcholinesterase; Brain parts; Inhibition in vivo; Quantitative histochemistry; Rat; Russian VX; VX

Indexed keywords

ACETYLCHOLINESTERASE; METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; NERVE GAS; RUSSIAN VX; UNCLASSIFIED DRUG; CHEMICAL WARFARE AGENT; CHOLINESTERASE INHIBITOR; PHOSPHOROTHIOIC ACID DERIVATIVE; S (N,N DIETHYLAMINOETHYL) ISOBUTYL METHYLPHOSPHOTHIOLATE; S-(N,N-DIETHYLAMINOETHYL) ISOBUTYL METHYLPHOSPHOTHIOLATE;

EID: 69449087766     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.1080/01480540802391062     Document Type: Article
Times cited : (8)

References (38)
  • 1
    • 33745184474 scopus 로고    scopus 로고
    • Application of kinetic-based computer modelling to evaluate the efficacy of HI-6 in percutaneous VX poisoning
    • Aurbek N, Thiermann H, Szinicz L, Eyer P, and Worek F (2006). Application of kinetic-based computer modelling to evaluate the efficacy of HI-6 in percutaneous VX poisoning. Toxicology 224, 74-80.
    • (2006) Toxicology , vol.224 , pp. 74-80
    • Aurbek, N.1    Thiermann, H.2    Szinicz, L.3    Eyer, P.4    Worek, F.5
  • 2
    • 34547879826 scopus 로고
    • Survey of chemicals for consideration as possible "v" agents (in Czech)
    • Bajgar J (1968). Survey of chemicals for consideration as possible "V" agents (in Czech). Inf. Zpravodaj. 9, 5-17.
    • (1968) Inf. Zpravodaj. , vol.9 , pp. 5-17
    • Bajgar, J.1
  • 3
    • 0017614170 scopus 로고
    • In vitro inhibition of soluble brain acetylcholinesterase by organophosphates of O-ethyl-S-(2- dialkylaminoethyl)-methylphosphonothiolate type
    • Bajgar J, and Patocka J (1977). In vitro inhibition of soluble brain acetylcholinesterase by organophosphates of O-ethyl-S-(2- dialkylaminoethyl)- methylphosphonothiolate type. Coll. Czechoslov. Chem. Commun. 42, 770-772.
    • (1977) Coll. Czechoslov. Chem. Commun. , vol.42 , pp. 770-772
    • Bajgar, J.1    Patocka, J.2
  • 4
    • 0026782285 scopus 로고
    • Biological monitoring of exposure to nerve agents
    • Bajgar J (1992). Biological monitoring of exposure to nerve agents. Br. J. Ind. Med. 49, 648-653.
    • (1992) Br. J. Ind. Med. , vol.49 , pp. 648-653
    • Bajgar, J.1
  • 5
    • 10044275708 scopus 로고    scopus 로고
    • Organophosphates/nerve agent poisoning: Mechanism of action, diagnosis, prophylaxis, and treatment
    • Bajgar J (2004). Organophosphates/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment. Adv. Clin. Chem. 38, 151-216.
    • (2004) Adv. Clin. Chem. , vol.38 , pp. 151-216
    • Bajgar, J.1
  • 6
    • 33748798909 scopus 로고    scopus 로고
    • Evaluation of reactivation test in anaesthetized dogs with experimental intoxication with nerve agents
    • Bajgar J, Fusek J, Bartosova L, Jun D, and Kuca K (2006). Evaluation of reactivation test in anaesthetized dogs with experimental intoxication with nerve agents. J. Appl. Toxicol. 26, 439-443.
    • (2006) J. Appl. Toxicol. , vol.26 , pp. 439-443
    • Bajgar, J.1    Fusek, J.2    Bartosova, L.3    Jun, D.4    Kuca, K.5
  • 7
    • 33845652252 scopus 로고    scopus 로고
    • Changes of acetylcholinesterase activity in different brain areas following intoxication with nerve agents: Biochemical and histochemical study
    • Bajgar J, Hajek P, Slizova D, Krs O, Fusek J, Kuca K, Jun D, Bartosova L, and Blaha V (2007a). Changes of acetylcholinesterase activity in different brain areas following intoxication with nerve agents: biochemical and histochemical study. Chem-Biol. Interact. 165, 14-21.
    • (2007) Chem-Biol. Interact. , vol.165 , pp. 14-21
    • Bajgar, J.1    Hajek, P.2    Slizova, D.3    Krs, O.4    Fusek, J.5    Kuca, K.6    Jun, D.7    Bartosova, L.8    Blaha, V.9
  • 9
    • 34249796659 scopus 로고    scopus 로고
    • Treatment of organophosphate intoxication using cholinesterase reactivators: Facts and fiction
    • Bajgar J, Fusek J, Kuca K, Bartosova L, and Jun D (2007c). Treatment of organophosphate intoxication using cholinesterase reactivators: facts and fiction. Mini-Rev. Med. Chem. 7, 461-466.
    • (2007) Mini-Rev. Med. Chem. , vol.7 , pp. 461-466
    • Bajgar, J.1    Fusek, J.2    Kuca, K.3    Bartosova, L.4    Jun, D.5
  • 10
    • 0037564066 scopus 로고    scopus 로고
    • A computerized image analysis system for quantitative analysis of cells in histological brain sections
    • DOI 10.1016/S0165-0270(03)00023-2
    • Benali A, Leefken I, Eysel U, and Weile E (2003). A computerized image analysis system for quantitative analysis of cells in histological brain sections. J. Neurosci. Meth. 125, 33-43. (Pubitemid 36579330)
    • (2003) Journal of Neuroscience Methods , vol.125 , Issue.1-2 , pp. 33-43
    • Benali, A.1    Leefken, I.2    Eysel, U.T.3    Weiler, E.4
  • 11
    • 31044442395 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of pyridinium oximes: Mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice, and their cytotoxicity
    • Calic M, Lucic Vrdoljak, Radic A, Jelic B, Jun D, Kuca D, and Kovarik KZ (2006). In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice, and their cytotoxicity. Toxicology 219, 85-96.
    • (2006) Toxicology , vol.219 , pp. 85-96
    • Calic, M.1    Vrdoljak, L.2    Radic, A.3    Jelic, B.4    Jun, D.5    Kuca, D.6    Kovarik, K.Z.7
  • 13
    • 0035990686 scopus 로고    scopus 로고
    • Pharmacological antagonism of lethal effects induced by O-isobutyl-/S-2- (diethylamino) ethyl/methylphosphonothioate
    • Chang FCT, Hoffman BE, and DeBus S (2002). Pharmacological antagonism of lethal effects induced by O-isobutyl-/S-2- (diethylamino) ethyl/ methylphosphonothioate. Drug Chem. Toxicol. 25, 321-337.
    • (2002) Drug Chem. Toxicol. , vol.25 , pp. 321-337
    • Chang, F.C.T.1    Hoffman, B.E.2    Debus, S.3
  • 14
    • 0017397857 scopus 로고
    • Environmental temperature and the percutaneous absorption of a cholinesterase inhibitor, VX
    • Craig FN, Cummings EG, and Sim VM (1977). Environmental temperature and the percutaneous absorption of a cholinesterase inhibitor, VX. J. Invest. Dermatol. 68, 358-361.
    • (1977) J. Invest. Dermatol. , vol.68 , pp. 358-361
    • Craig, F.N.1    Cummings, E.G.2    Sim, V.M.3
  • 15
    • 33745664204 scopus 로고    scopus 로고
    • Development of a dynamic model for real-time determination of membranebound acetylcholinesterase activity upon perfusion with inhibitors and reactivators
    • Eckert S, Eyer P, Muckter H, and Worek F (2006). Development of a dynamic model for real-time determination of membranebound acetylcholinesterase activity upon perfusion with inhibitors and reactivators. Biochem. Pharmacol. 72, 344-357.
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 344-357
    • Eckert, S.1    Eyer, P.2    Muckter, H.3    Worek, F.4
  • 19
    • 0023157099 scopus 로고
    • Biochemical and histochemical alterations following acute soman intoxication in the rat
    • Gupta RC, Patterson GT, and Dettbarn W-D (1987). Biochemical and histochemical alterations following acute soman intoxication in the rat. Toxicol. Appl. Pharmacol. 87, 393-402.
    • (1987) Toxicol. Appl. Pharmacol. , vol.87 , pp. 393-402
    • Gupta, R.C.1    Patterson, G.T.2    Dettbarn, W.-D.3
  • 20
    • 0033866652 scopus 로고    scopus 로고
    • Cholinergic and noncholinergic brain biomarkers of insecticide exposure and effects
    • Gupta RC, Goad JT, Milatovic D, and Dettbarn W-D (2000). Cholinergic and noncholinergic brain biomarkers of insecticide exposure and effects. Hum. Exp. Toxicol. 19, 297-308.
    • (2000) Hum. Exp. Toxicol. , vol.19 , pp. 297-308
    • Gupta, R.C.1    Goad, J.T.2    Milatovic, D.3    Dettbarn, W.-D.4
  • 21
    • 1942437974 scopus 로고    scopus 로고
    • Brain regional heterogeneity and toxicological mechanisms of organophosphates and carbamates
    • Gupta RC (2004). Brain regional heterogeneity and toxicological mechanisms of organophosphates and carbamates. Toxicol. Mech. Meth. 14, 103-143.
    • (2004) Toxicol. Mech. Meth. , vol.14 , pp. 103-143
    • Gupta, R.C.1
  • 22
    • 33744997416 scopus 로고    scopus 로고
    • Comparison of changes in AChE activity in the brain of the laboratory rat after soman and tabun intoxication
    • Hajek P, Slizova D, Krs O, and Bajgar J (2005). Comparison of changes in AChE activity in the brain of the laboratory rat after soman and tabun intoxication. Biomed. Papers 148, 209-211.
    • (2005) Biomed. Papers , vol.148 , pp. 209-211
    • Hajek, P.1    Slizova, D.2    Krs, O.3    Bajgar, J.4
  • 23
    • 0030271985 scopus 로고    scopus 로고
    • Quantitative, video-based histochemistry to measure regional effects of anticholinesterase pesticides in rat brain
    • Hammond PI, Jelacic T, Padilla S, and Brimijoin S (1996). Quantitative, video-based histochemistry to measure regional effects of anticholinesterase pesticides in rat brain. Anal. Biochem. 241, 82-92.
    • (1996) Anal. Biochem. , vol.241 , pp. 82-92
    • Hammond, P.I.1    Jelacic, T.2    Padilla, S.3    Brimijoin, S.4
  • 24
    • 33748654623 scopus 로고    scopus 로고
    • The reactivating and therapeutical efficacy of oximes to counteract Russian VX poisoning
    • Kassa J, Kuca K, and Jun D (2006). The reactivating and therapeutical efficacy of oximes to counteract Russian VX poisoning. Int. J. Toxicol. 25, 397-401.
    • (2006) Int. J. Toxicol. , vol.25 , pp. 397-401
    • Kassa, J.1    Kuca, K.2    Jun, D.3
  • 25
    • 15844422691 scopus 로고    scopus 로고
    • Reactivation of organophosphate- inhibited acetylcholinesterase by quaternary pyridinium aldoximes
    • Kuca K, Patocka J, Cabal J, and Jun D (2004). Reactivation of organophosphate- inhibited acetylcholinesterase by quaternary pyridinium aldoximes. Neurotox. Res. 6, 565-570.
    • (2004) Neurotox. Res. , vol.6 , pp. 565-570
    • Kuca, K.1    Patocka, J.2    Cabal, J.3    Jun, D.4
  • 28
    • 0029908459 scopus 로고    scopus 로고
    • Organophosphate anticholinesterase poisoning
    • Marrs TC (1996). Organophosphate anticholinesterase poisoning. Toxic Subst. Mech. 15, 357-388.
    • (1996) Toxic Subst. Mech. , vol.15 , pp. 357-388
    • Marrs, T.C.1
  • 29
    • 70749158411 scopus 로고
    • Interaction of O-ethyl S-(2- dimethylaminoethyl) methylthiophosphonate with acetylcholinesterase
    • Patocka J, and Tulach J (1969). Interaction of O-ethyl S-(2- dimethylaminoethyl) methylthiophosphonate with acetylcholinesterase. Coll. Czechoslov. Chem. Commun. 34, 3191-3195.
    • (1969) Coll. Czechoslov. Chem. Commun. , vol.34 , pp. 3191-3195
    • Patocka, J.1    Tulach, J.2
  • 31
    • 31644432758 scopus 로고    scopus 로고
    • Five oximes (K-27, K33, K-48, BI-6, and methoxime) in comparison with pralidoxime: In vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon
    • Petroianu GA, Arafat K, Kuca K, and Kassa J (2006a). Five oximes (K-27, K33, K-48, BI-6, and methoxime) in comparison with pralidoxime: in vitro reactivation of red blood cell acetylcholinesterase inhibited by paraoxon. J. Appl. Toxicol. 26, 64-71.
    • (2006) J. Appl. Toxicol. , vol.26 , pp. 64-71
    • Petroianu, G.A.1    Arafat, K.2    Kuca, K.3    Kassa, J.4
  • 32
    • 33646831462 scopus 로고    scopus 로고
    • Five oximes (K-27, K-33, K-48, BI-6 and methoxime) in comparison with pralidoxime: Survival in rats exposed to the organophosphate paraoxon
    • DOI 10.1002/jat.1143
    • Petroianu GA, Nurulain SM, Nagelkerke N, Al-Sultan MAH, Kuca K, and Kassa J (2006b). Five oximes (K-27, K-33, K-48, BI-6, and methoxime) in comparison with pralidoxime: survival of rats exposed to the organophosphate paraoxon. J Appl Toxicol. 26, 262-268. (Pubitemid 43773887)
    • (2006) Journal of Applied Toxicology , vol.26 , Issue.3 , pp. 262-268
    • Petroianu, G.A.1    Nurulain, S.M.2    Nagelkerke, N.3    Al-Sultan, M.A.H.4    Kuca, K.5    Kassa, J.6
  • 33
    • 0042338743 scopus 로고    scopus 로고
    • Nerve attacks on children: Diagnosis and management
    • Rotenberg JS, and Newmark J (2003). Nerve attacks on children: diagnosis and management. Pediatrics 112, 648-658.
    • (2003) Pediatrics , vol.112 , pp. 648-658
    • Rotenberg, J.S.1    Newmark, J.2
  • 34
    • 28744453050 scopus 로고    scopus 로고
    • In vivo cholinesterase inhibitory specificity of organophosphorus nerve agents
    • Shih TM, Kan RK, and McDonough JH (2005). In vivo cholinesterase inhibitory specificity of organophosphorus nerve agents. Chem-Biol. Interact. 157-158, 293-303.
    • (2005) Chem-Biol. Interact. , vol.157-158 , pp. 293-303
    • Shih, T.M.1    Kan, R.K.2    McDonough, J.H.3
  • 35
    • 0015964160 scopus 로고
    • The reactivatability of cholinesterase inhibited by VX and sarin in man
    • Sidell FR, and Groff WA (1974). The reactivatability of cholinesterase inhibited by VX and sarin in man. Toxicol. Appl. Pharmacol. 27, 241-252.
    • (1974) Toxicol. Appl. Pharmacol. , vol.27 , pp. 241-252
    • Sidell, F.R.1    Groff, W.A.2
  • 36
    • 0015861522 scopus 로고
    • The reversal of anticholinergic intoxication in man with the cholinesterase inhibitor VX
    • Sidell FR, Aghajanian GK, and Groff WA (1973). The reversal of anticholinergic intoxication in man with the cholinesterase inhibitor VX. Proc. Soc. Exp. Biol. Med. 144, 725-730.
    • (1973) Proc. Soc. Exp. Biol. Med. , vol.144 , pp. 725-730
    • Sidell, F.R.1    Aghajanian, G.K.2    Groff, W.A.3
  • 38
    • 2342435029 scopus 로고    scopus 로고
    • Nerve agents: A comprehensive review
    • Wiener SW, and Hoffman RS (2004). Nerve agents: a comprehensive review. J. Int. Care Med. 19, 22-37.
    • (2004) J. Int. Care Med. , vol.19 , pp. 22-37
    • Wiener, S.W.1    Hoffman, R.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.