Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen

Arthritis and Rheumatism

Volumn 60, Issue 9, 2009, Pages 2684-2693

  Allen, Kyle D ^a   Griffin, Timothy M ^a   Rodriguiz, Ramona M ^a   Wetsel, William C ^a   Kraus, Virginia B ^a   Huebner, Janet L ^a   Boyd, Lawrence M ^a   Setton, Lori A ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 9; HYALURONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; BLOOD LEVEL; CADAVER; CARTILAGE INJURY; CLIMBING; CONTROLLED STUDY; COORDINATION; DISEASE ASSOCIATION; FEMALE; FUNCTIONAL DISEASE; GAIT; GRIP STRENGTH; HEAT SENSITIVITY; HISTOLOGY; HOT PLATE TEST; INCIDENCE; INTERVERTEBRAL DISK DEGENERATION; KNEE; LOCOMOTION; MALE; MECHANICAL STIMULATION; MOBILIZATION; MOUSE; NOCICEPTION; NONHUMAN; OSTEOARTHRITIS; PHENOTYPE; PHYSICAL CAPACITY; PRIORITY JOURNAL; REFLEX; ROTAROD TEST; SENSITIVITY ANALYSIS; SENSORIMOTOR FUNCTION; SKILL; SPINE; STANDING; SYMPTOMATOLOGY; TAIL FLICK TEST; THERMAL ANALYSIS; VELOCITY; WALKING; WILD TYPE;

ANIMALS; ARTHRALGIA; BIOMECHANICS; COLLAGEN TYPE IX; DISEASE MODELS, ANIMAL; FEMALE; GAIT; HYALURONIC ACID; INTERVERTEBRAL DISK; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, GENETIC; MOTOR ACTIVITY; OSTEOARTHRITIS; SEVERITY OF ILLNESS INDEX;

EID: 69449087603     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24783     Document Type: Article

References (49)

1. The burden of musculoskeletal diseases in the United States: prevalence, societal and economic cost. Rosemont (IL): American Academy of Orthopaedic Surgeons; 2008.
2. Battie MC, Videman T, Parent E. Lumbar disc degeneration: epidemiology and genetic influences. Spine 2004;29:2679-2690 (Pubitemid 40353254)
3. Bierma-Zeinstra SM, Koes BW. Risk factors and prognostic factors of hip and knee osteoarthritis. Nat Clin Pract Rheumatol 2007;3:78-85. (Pubitemid 46267752)
4. Reginato AM, Olsen BR. The role of structural genes in the pathogenesis of osteoarthritic disorders. Arthritis Res 2002;4:337-345 (Pubitemid 35364002)
5. Alizadeh BZ, Njajou OT, Bijkerk C, Meulenbelt I, Wildt SC, Hofman A, et al. Evidence for a role of the genomic region of the gene encoding for the α1 chain of type IX collagen (COL9A1) in hip osteoarthritis: a population-based study. Arthritis Rheum 2005;52:1437-1442 (Pubitemid 40663935)
6. Ikeda T, Mabuchi A, Fukuda A, Kawakami A, Ryo Y, Yamamoto S, et al. Association analysis of single nucleotide polymorphisms in cartilage-specific collagen genes with knee and hip osteoarthritis in the Japanese population. J Bone Miner Res 2002;17:1290-1296 (Pubitemid 34680506)
7. Paassilta P, Lohiniva J, Goring HH, Perala M, Raina SS, Karppinen J, et al. Identification of a novel common genetic risk factor for lumbar disk disease. JAMA 2001;285:1843-1849 (Pubitemid 32289151)
8. Jim JJ, Noponen-Hietala N, Cheung KM, Ott J, Karppinen J, Sahraravand A, et al. The TRP2 allele of COL9A2 is an age-dependent risk factor for the development and severity of intervertebral disc degeneration. Spine 2005;30:2735-2742 (Pubitemid 43011033)
9. Higashino K, Matsui Y, Yagi S, Takata Y, Goto T, Sakai T, et al. The α2 type IX collagen tryptophan polymorphism is associated with the severity of disc degeneration in younger patients with herniated nucleus pulposus of the lumbar spine. Int Orthop 2007;31:107-111 (Pubitemid 46208232)
10. Seki S, Kawaguchi Y, Mori M, Mio F, Chiba K, Mikami Y, et al. Association study of COL9A2 with lumbar disc disease in the Japanese population. J Hum Genet 2006;51:1063-1067 (Pubitemid 44800724)
11. Eyre DR. Collagens and cartilage matrix homeostasis. Clin Orthop Relat Res 2004(427 Suppl):S118-22.
12. Fassler R, Schnegelsberg PN, Dausman J, Shinya T, Muragaki Y, McCarthy MT, et al. Mice lacking α1 (IX) collagen develop noninflammatory degenerative joint disease. Proc Natl Acad Sci U S A 1994;91:5070-5074 (Pubitemid 24177794)
13. Boyd LM, Richardson WJ, Allen KD, Flahiff C, Jing L, Li Y, et al. Early-onset degeneration of the intervertebral disc and vertebral end plate in mice deficient in type IX collagen. Arthritis Rheum 2008;58:164-171
14. Hu K, Xu L, Cao L, Flahiff CM, Brussiau J, Ho K, et al. Pathogenesis of osteoarthritis-like changes in the joints of mice deficient in type IX collagen. Arthritis Rheum 2006;54:2891-2900 (Pubitemid 44497768)
15. Kraus VB. Biomarkers in osteoarthritis. Curr Opin Rheumatol 2005;17:641-646
16. Rodriguiz RM, Wetsel WC. Assessments of cognitive deficits in mutant mice. In: Levin ED, Buccafusco JJ, editors. Animal models of cognitive impairment. Boca Raton (FL): CRC Press; 2006. p. 223-282
17. Hedrick T, Reinschmidt C. DLTdataviewer2, custom MATLAB software. URL: http://www.unc.edu/~thedrick/software1.html.
18. Fuchs PN, Roza C, Sora I, Uhl G, Raja SN. Characterization of mechanical withdrawal responses and effects of mu-, delta- and kappa-opioid agonists in normal and mu-opioid receptor knockout mice. Brain Res 1999;821:480-486 (Pubitemid 29222812)
19. Elliott AL, Kraus VB, Luta G, Stabler T, Renner JB, Woodard J, et al. Serum hyaluronan levels and radiographic knee and hip osteoarthritis in African Americans and Caucasians in the Johnston County Osteoarthritis Project. Arthritis Rheum 2005;52:105-111 (Pubitemid 40129238)
20. Ward BD, Furman BD, Huebner JL, Kraus VB, Guilak F, Olson SA. Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse. Arthritis Rheum 2008;58:744-753
21. Boos N, Weissbach S, Rohrbach H, Weiler C, Spratt KF, Nerlich AG. Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in basic science. Spine 2002;27:2631-2644
22. Furman BD, Strand J, Hembree WC, Ward BD, Guilak F, Olson SA. Joint degeneration following closed intraarticular fracture in the mouse knee: a model of posttraumatic arthritis. J Orthop Res 2007;25:578-592 (Pubitemid 46730511)
23. Xu L, Flahiff CM, Waldman BA, Wu D, Olsen BR, Setton LA, et al. Osteoarthritis-like changes and decreased mechanical function of articular cartilage in the joints of mice with the chondrodysplasia gene (cho). Arthritis Rheum 2003;48:2509-2518 (Pubitemid 37129428)
24. Carlson CS, Guilak F, Vail TP, Gardin JF, Kraus VB. Synovial fluid biomarker levels predict articular cartilage damage following complete medial meniscectomy in the canine knee. J Orthop Res 2002;20:92-100. (Pubitemid 34071426)
25. Witte TH, Knill K, Wilson AM. Determination of peak vertical ground reaction force from duty factor in the horse (Equus caballus). J Exp Biol 2004;207(Pt 21):3639-3648 (Pubitemid 39484182)
26. Alexander RM. Principles of animal locomotion. Princeton (NJ): Princeton University Press; 2003.
27. Jordan K, Challis JH, Newell KM. Walking speed influences on gait cycle variability. Gait Posture 2007;26:128-134 (Pubitemid 46617938)
28. Khumsap S, Clayton HM, Lanovaz JL, Bouchey M. Effect of walking velocity on forelimb kinematics and kinetics. Equine Vet J Suppl 2002 Sep:325-329
29. Derrick TR, Hamill J, Caldwell GE. Energy absorption of impacts during running at various stride lengths. Med Sci Sports Exerc 1998;30:128-135 (Pubitemid 28071393)
30. Chen CP, Chen MJ, Pei YC, Lew HL, Wong PY, Tang SF. Sagittal plane loading response during gait in different age groups and in people with knee osteoarthritis. Am J Phys Med Rehabil 2003;82:307-312
31. Cheing GL, Hui-Chan CW. The motor dysfunction of patients with knee osteoarthritis in a Chinese population. Arthritis Rheum 2001;45:62-68
32. Lee TH, Tsuchida T, Kitahara H, Moriya H. Gait analysis before and after unilateral total knee arthroplasty: study using a linear regression model of normal controls - women without arthropathy. J Orthop Sci 1999;4:13-21. (Pubitemid 29058544)
33. Fernihough J, Gentry C, Bevan S, Winter J. Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of osteoarthritis. Neurosci Lett 2005;388:75-80. (Pubitemid 41206735)
34. Bove SE, Laemont KD, Brooker RM, Osborn MN, Sanchez BM, Guzman RE, et al. Surgically induced osteoarthritis in the rat results in the development of both osteoarthritis-like joint pain and secondary hyperalgesia. Osteoarthritis Cartilage 2006;14:1041-1048
35. McDougall JJ, Watkins L, Li Z. Vasoactive intestinal peptide (VIP) is a modulator of joint pain in a rat model of osteoarthritis. Pain 2006;123:98-105. (Pubitemid 43816762)
36. Beyreuther B, Callizot N, Stohr T. Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain. Arthritis Res Ther 2007;9:R14. (Pubitemid 46782774)
37. Tachihara H, Kikuchi S, Konno S, Sekiguchi M. Does facet joint inflammation induce radiculopathy?: an investigation using a rat model of lumbar facet joint inflammation. Spine 2007;32:406-412
38. Winkelstein BA, Weinstein JN, DeLeo JA. The role of mechanical deformation in lumbar radiculopathy: an in vivo model. Spine 2002;27:27-33.
39. Murata Y, Onda A, Rydevik B, Takahashi I, Takahashi K, Olmarker K. Changes in pain behavior and histologic changes caused by application of tumor necrosis factor-α to the dorsal root ganglion in rats. Spine 2006;31:530-535
40. Asamura K, Abe S, Imamura Y, Aszodi A, Suzuki N, Hashimoto S, et al. Type IX collagen is crucial for normal hearing. Neuroscience 2005;132:493-500. (Pubitemid 40417920)
41. Suzuki N, Asamura K, Kikuchi Y, Takumi Y, Abe S, Imamura Y, et al. Type IX collagen knock-out mouse shows progressive hearing loss. Neurosci Res 2005;51:293-298 (Pubitemid 40248552)
42. Silberberg M, Silberberg R. Role of sex hormone in the pathogenesis of osteoarthrosis of mice. Lab Invest 1963;12:285-289
43. Sokoloff L. Natural history of degenerative joint disease in small laboratory animals. I. Pathological anatomy of degenerative joint disease in mice. AMA Arch Pathol 1956;62:118-128
44. Ma HL, Blanchet TJ, Peluso D, Hopkins B, Morris EA, Glasson SS. Osteoarthritis severity is sex dependent in a surgical mouse model. Osteoarthritis Cartilage 2007;15:695-700. (Pubitemid 46760614)
45. Van Osch GJ, van der Kraan PM, Vitters EL, Blankevoort L, van den Berg WB. Induction of osteoarthritis by intra-articular injection of collagenase in mice: strain and sex related differences. Osteoarthritis Cartilage 1993;1:171-177
46. Sniekers YH, Weinans H, Bierma-Zeinstra SM, van Leeuwen JP, van Osch GJ. Animal models for osteoarthritis: the effect of ovariectomy and estrogen treatment - a systematic approach. Osteoarthritis Cartilage 2008;16:533-541
47. Walton M. Degenerative joint disease in the mouse knee: histologic observations. J Pathol 1977;123:109-122 (Pubitemid 8198650)
48. Carlsen S, Nandakumar KS, Holmdahl R. Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity. Arthritis Res Ther 2006;8:R102.
49. Holmdahl R, Jansson L, Andersson M, Jonsson R. Genetic, hormonal and behavioural influence on spontaneously developing arthritis in normal mice. Clin Exp Immunol 1992;88:467-472