Skin reaction secondary to treatment with Iressa (ZD1839);Reacción cutánea secundaria a tratamiento con Iressa (ZD1839)

Actas Dermo-Sifiliograficas

Volumn 95, Issue 7, 2004, Pages 459-461

  Isarría, María José ^a   Alonso, Ignacio ^a   Segurado, Agustina ^a   Ortiz, Javier ^a   Vanaclocha, Francisco ^a  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

Author keywords

Cutaneous side effects; Epidermal growth factor receptor; Iressa (ZD1839)

Indexed keywords

CARBOPLATIN; GEFITINIB; GEMCITABINE;

AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; FOLLICULITIS; HISTOPATHOLOGY; HUMAN; LUNG CARCINOMA; MALE; PUSTULE; SKIN BIOPSY; SKIN MANIFESTATION; SQUAMOUS CELL CARCINOMA; TREATMENT OUTCOME;

EID: 6944241155     PISSN: 00017310     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0001-7310(04)76859-3     Document Type: Article

References (10)

1. Baselga J, Averbuch SD. ZD1839 («Iressa») as an anticancer agent. Drugs 2000;60(Suppl 1):33-40.
2. Baselga J. New therapeutic agents targeting the epidermal growth factor receptor. J Clin Oncol 2000;18(Suppl 21):54-9.
3. Zandwijk NV. Tolerability of gefitinib in patients receiving treatment in everyday clinical practice. Br J Cancer 2003;89(Suppl 2):9-14.
4. Van Doorn R, Kirtschig G, Scheffer E, Stoof TJ, Giaccone G. Follicular and epidermal alterations in patients treated with ZD1839 (Iressa), an inhibitor of the epidermal growth factor receptor. Br J Dermatol 2002;147;598-601.
5. Kimyai-Asadi A. Follicular toxic effects of chimeric anti-epidermal growth factor receptor antibody cetuximab used to treat human solid tumors. Arch Dermatol 2002;138:129-30.
6. Busam KJ, Capodieci P, Motzer R, Kiehn T, Phelan D, Halpern C. Cutaneus side-effects in cancer patients treated with the antiepidermal growth factor receptor antibody C225. Br J Dermatol 2001;144:1169-76.
7. Nanney LB, Magid M, Stoscheck CM, King LE. Comparison of epidermal growth factor binding and receptor distribution in normal human epidermis and epidermal appendages. J Invest Dermatol 1984;83:385-93.
8. Jost M, Kari C, Rodeck U. The EGF receptor, an essential regulator of multiple epidermal functions. Eur J Dermatol 2000;10:505-10.
9. Peus D, Harnacher L, Pittelkow MR. EGF-receptor tyrosine kinase inhibition induces keratinocyte growth arrest and terminal differentation. J Invest Dermatol 1997;109:751-6.
10. Philpott MP, Kealey T. Effects of EGF on the morphology and patterns of DNA synthesis in isolated human hair follicles. J Invest Dermatol 1994;102:186-91.