The LIM-Homeodomain Protein ISL1 Activates Insulin Gene Promoter Directly through Synergy with BETA2

Journal of Molecular Biology

Volumn 392, Issue 3, 2009, Pages 566-577

  Zhang, Hui ^a   Wang, Wei Ping ^a   Guo, Ting ^a   Yang, Ji Chun ^a   Chen, Ping ^a   Ma, Kang Tao ^a   Guan, You Fei ^a   Zhou, Chun Yan ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

BETA2; insulin gene expression; ISL1; protein interactions; transcriptional factors

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; HOMEODOMAIN PROTEIN; INSULIN; ISLET FACTOR 1; LIM PROTEIN; MESSENGER RNA; NEUROGENIC DIFFERENTIATION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RAT; TRANSCRIPTION INITIATION; UPREGULATION;

RATTUS;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HOMEODOMAIN PROTEINS; HUMANS; INSULIN; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; PROMOTER REGIONS, GENETIC; RATS; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION, GENETIC;

EID: 69349092182     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.07.036     Document Type: Article

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