The possible cellular mechanism for extending lifespan of mice with Rapamycin

Biological Procedures Online

Volumn 11, Issue 1, 2009, Pages 1-2

  Li, Shulin ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN;

CD8+ T LYMPHOCYTE; CELL CYCLE; CELL DEATH; CELL SURVIVAL; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; FATTY ACID OXIDATION; LIFESPAN; MEMORY T LYMPHOCYTE; NONHUMAN; RNA INTERFERENCE; SHORT SURVEY; SIGNAL TRANSDUCTION;

MUS;

EID: 69349090609     PISSN: 14809222     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12575-009-9015-y     Document Type: Short Survey

References (3)

1. Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wikinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E and Miller RA (2009) Rapamycin fed late in life extends lifespan in genetically heterogenous mice. Nature. doi: 10.1038/nature08221
2. Araki K, Turner AP, Shaffer VO, Gangappa S, Keller SA, Bachmann MF, Larsen CP, and Ahmed R (2009) mTOR regulates memory CD8 T-cell differentiation. Nature. doi: 10.1038/nature08155
3. Pearce EL, Walsh MC, Cejas PF, Harms GM, Shen H, Wang LS, Jones RG and Choi Y (2009) Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature. doi: 10.1038/nature08097