Characterization of Ebolavirus regulatory genomic regions

Virus Research

Volumn 144, Issue 1-2, 2009, Pages 1-7

  Neumann, Gabriele ^a   Watanabe, Shinji ^a   Kawaoka, Yoshihiro ^a,b,c,d  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b THE UNIVERSITY OF TOKYO   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

Ebolavirus; Intergenic region (IGR); Minireplicon; Nontranslated region (NTR); Transcription

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; DNA; LUCIFERASE; RIBOZYME; RNA POLYMERASE; VIRUS PROTEIN;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; CISTRON; CONTROLLED STUDY; DNA FLANKING REGION; DNA MODIFICATION; EBOLA VIRUS; FILOVIRUS; GENE DELETION; GENE SEQUENCE; GENETIC CONSERVATION; GENETIC REGULATION; HUMAN; HUMAN CELL; MARBURG VIRUS; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REPLICON; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; VIRAL GENETICS;

3' UNTRANSLATED REGIONS; 5' UNTRANSLATED REGIONS; DNA, INTERGENIC; EBOLAVIRUS; GENE EXPRESSION REGULATION, VIRAL; PODOVIRIDAE; REGULATORY SEQUENCES, NUCLEIC ACID; RNA, CATALYTIC; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC;

EBOLA VIRUS; MARBURGVIRUS;

EID: 69249230807     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virusres.2009.02.005     Document Type: Article

References (21)

1. Boehmann Y., Enterlein S., Randolf A., and Muhlberger E. A reconstituted replication and transcription system for Ebola virus Reston and comparison with Ebola virus Zaire. Virology 332 1 (2005) 406-417
2. Collins P.L., Olmsted R.A., Spriggs M.K., Johnson P.R., and Buckler-White A.J. Gene overlap and site-specific attenuation of transcription of the viral polymerase L gene of human respiratory syncytial virus. Proc. Natl. Acad. Sci. U.S.A. 84 15 (1987) 5134-5138
3. Fearns R., and Collins P.L. Model for polymerase access to the overlapped L gene of respiratory syncytial virus. J. Virol. 73 1 (1999) 388-397
4. Feldmann H., Klenk H.D., and Sanchez A. Molecular biology and evolution of filoviruses. Arch. Virol. Suppl. 7 (1993) 81-100
5. Feldmann H., Muhlberger E., Randolf A., Will C., Kiley M.P., Sanchez A., and Klenk H.D. Marburg virus, a filovirus: messenger RNAs, gene order, and regulatory elements of the replication cycle. Virus Res. 24 1 (1992) 1-19
6. Finke S., Cox J.H., and Conzelmann K.K. Differential transcription attenuation of rabies virus genes by intergenic regions: generation of recombinant viruses overexpressing the polymerase gene. J. Virol. 74 16 (2000) 7261-7269
7. Muhlberger E., Sanchez A., Randolf A., Will C., Kiley M.P., Klenk H.D., and Feldmann H. The nucleotide sequence of the L gene of Marburg virus, a filovirus: homologies with paramyxoviruses and rhabdoviruses. Virology 187 2 (1992) 534-547
8. Muhlberger E., Trommer S., Funke C., Volchkov V., Klenk H.D., and Becker S. Termini of all mRNA species of Marburg virus: sequence and secondary structure. Virology 223 2 (1996) 376-380
9. Muhlberger E., Weik M., Volchkov V.E., Klenk H.D., and Becker S. Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems. J. Virol. 73 3 (1999) 2333-2342
10. Neumann G., Feldmann H., Watanabe S., Lukashevich I., and Kawaoka Y. Reverse genetics demonstrates that proteolytic processing of the Ebola virus glycoprotein is not essential for replication in cell culture. J. Virol. 76 1 (2002) 406-410
11. Rose R.E. The nucleotide sequence of pACYC177. Nucl. Acids Res. 16 1 (1988) 356
12. Sanchez A., Geisbert T.W., and Feldmann H. Filoviridae: Marburg and Ebola viruses. In: Knipe D.M., Howley P.M., Griffin D.E., Lamb R.A., Martin M.A., Roizman B., and Straus S.E. (Eds). Fields Virology. 5th ed. (2007), Lippincott Williams & Wilkins, Philadelphia 1409-1448
13. Sanchez A., Kiley M.P., Holloway B.P., and Auperin D.D. Sequence analysis of the Ebola virus genome: organization, genetic elements, and comparison with the genome of Marburg virus. Virus Res. 29 3 (1993) 215-240
14. Sanchez A., Kiley M.P., Holloway B.P., McCormick J.B., and Auperin D.D. The nucleoprotein gene of Ebola virus: cloning, sequencing, and in vitro expression. Virology 170 1 (1989) 81-91
15. Sanchez A., Kiley M.P., Klenk H.D., and Feldmann H. Sequence analysis of the Marburg virus nucleoprotein gene: comparison to Ebola virus and other non-segmented negative-strand RNA viruses. J. Gen. Virol. 73 2 (1992) 347-357
16. Stillman E.A., and Whitt M.A. The length and sequence composition of vesicular stomatitis virus intergenic regions affect mRNA levels and the site of transcript initiation. J. Virol. 72 7 (1998) 5565-5572
17. Theriault S., Groseth A., Neumann G., Kawaoka Y., and Feldmann H. Rescue of Ebola virus from cDNA using heterologous support proteins. Virus Res. 106 1 (2004) 43-50
18. Volchkov V.E., Volchkova V.A., Muhlberger E., Kolesnikova L.V., Weik M., Dolnik O., and Klenk H.D. Recovery of infectious Ebola virus from complementary DNA: RNA editing of the GP gene and viral cytotoxicity. Science 291 5510 (2001) 1965-1969
19. Watanabe S., Watanabe T., Noda T., Takada A., Feldmann H., Jasenosky L.D., and Kawaoka Y. Production of novel ebola virus-like particles from cDNAs: an alternative to ebola virus generation by reverse genetics. J. Virol. 78 2 (2004) 999-1005
20. Weik M., Enterlein S., Schlenz K., and Muhlberger E. The Ebola virus genomic replication promoter is bipartite and follows the rule of six. J. Virol. 79 16 (2005) 10660-10671
21. Weik M., Modrof J., Klenk H.D., Becker S., and Muhlberger E. Ebola virus VP30-mediated transcription is regulated by RNA secondary structure formation. J. Virol. 76 17 (2002) 8532-8539