Unifying electron transfer mechanism for psilocybin and psilocin

Medical Hypotheses

Volumn 73, Issue 4, 2009, Pages 626-

  Kovacic, Peter ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ACETYLSALICYLIC ACID; AMPHETAMINE; DIAMORPHINE; METHAMPHETAMINE; MORPHINE; PHENOBARBITAL; PSILOCIN; PSILOCYBINE;

DRUG ABUSE; ELECTRON TRANSPORT; LETTER; MUSHROOM; OXIDATION; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; SEROTONINERGIC SYSTEM;

ELECTROCHEMISTRY; ELECTRON TRANSPORT; HUMANS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; OXIDATION-REDUCTION; OXIDATIVE STRESS; PSILOCYBINE; REACTIVE OXYGEN SPECIES; STREET DRUGS; SUBSTANCE-RELATED DISORDERS;

EID: 69249230748     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2009.06.022     Document Type: Letter

References (5)

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2. Kovacic P, Somanathan R. Novel unifying mechanism for mescaline in the central nervous system: electrochemistry, catechol redox metabolite, receptor, cell signaling, and structure activity relationship. Oxidat Med Cell Longev [in press].
3. Blaschko H., and Levine W.G. Enzymic oxidation of psilocine and other hydroxyindoles. Biochem Pharmacol 3 (1960) 168-169
4. Horita A., and Weber L.G. The enzymic dephosphorylation and oxidation of psilocybin and psilocin by mammalian tissue homogenates. Biochem Pharmacol 7 (1961) 47-54
5. Passie T., Seifert G., Schneider U., and Enrich H.M. The pharmacology of psilocybin. Addict Biol 7 (2002) 357-364