Bulky extramedullary hematopoiesis is not a rare complication of congenital dyserythropoietic anemia

Annals of Hematology

Volumn 88, Issue 10, 2009, Pages 937-941

  Heimpel, Hermann ^a   Dührsen, Ulrich ^b   Hofbauer, P ^c   Rigamonti Wermlinger, V ^d   Kreuser, Ernst Dietrich ^e   Schwarz, Klaus ^a   Solenthaler, Max ^d   Pauls, S ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

^c Fachpraxis für Lungenkrankheiten   (Germany)

^d UNIVERSITY OF BERN   (Switzerland)

^e Krankenhaus der Barmherzigen Bruder   (Germany)

Author keywords

Congenital dyserythropoietic anemia; Extramedullary hematopoiesis; Imaging techniques

Indexed keywords

HYDROXYUREA; TRANSCRIPTION FACTOR GATA 1;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONGENITAL DYSERYTHROPOIETIC ANEMIA; ERYTHROBLAST; EXTRAMEDULLARY HEMATOPOIESIS; FEMALE; GENE MUTATION; HEART FAILURE; HUMAN; LUNG EMBOLISM; MALE; NEUROPATHIC PAIN; NUCLEAR MAGNETIC RESONANCE IMAGING; PLEURA EFFUSION; PREVALENCE; PRIORITY JOURNAL; RESPIRATORY DISTRESS; SPLENECTOMY; THORACIC SPINE; THORACOTOMY; THORAX RADIOGRAPHY; THROMBOCYTOPENIA;

ADOLESCENT; ADULT; AGED; ANEMIA, DYSERYTHROPOIETIC, CONGENITAL; DATA COLLECTION; DIAGNOSIS, DIFFERENTIAL; DIAGNOSTIC IMAGING; FEMALE; HEMATOPOIESIS, EXTRAMEDULLARY; HUMANS; MALE; MIDDLE AGED; SPINE; THORACIC VERTEBRAE;

EID: 69249220174     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00277-009-0735-5     Document Type: Article

References (18)

1. Taher A, Isma'eel H, Cappellini MD (2006) Thalassemia intermedia: revisited. Blood Cells Mol Dis 37:12-20. doi: 10.1016/j.bcmd.2006.04.005
2. Gumbs RV, Higginbotham-Ford EA, Teal JS, Kletter GG, Castro O (1987) Thoracic extramedullary hematopoiesis in sickle-cell disease. AJR Am J Roentgenol 149:889-893
3. Bastion Y, Coiffier B, Felman P, Assouline D, Tigaud J-D, Espinouse D, Bryon P-A (1990) Massive mediastinal extramedullary hematopoiesis in hereditary spherocytosis: A case report. Am J Hematol 35:263-265. doi: 10.1002/ajh.2830350408
4. Pulsoni A et al (1992) Mediastinal extramedullary hematopoiesis as first manifestation of hereditary spherocytosis. Ann Hematol 65:196-198. doi: 10.1007/BF01703115
5. Plensa E, Tapia G, Junca J, Perez R, Castella E, Marti S (2005) Paravertebral extramedullary hematopoiesis due to pyruvate kinase deficiency. Haematologica 90 Suppl:ECR32.:ECR32
6. Bowling MR, Cauthen CG, Perry CD, Patel NP, Bergman S, Link KM, Sane AC, Conforti JF (2008) Pulmonary extramedullary hematopoiesis. J Thorac Imaging 23:138-141. doi: 10.1097/RTI.0b013e31815b89aa
7. Heimpel H, Anselstetter V, Chrobak L, Denecke J, Einsiedler B, Gallmeier K, Griesshammer A, Marquardt T, Janka-Schaub G, Kron M, Kohne E (2003) Congenital dyserythropoietic anemia type II: Epidemiology, clinical appearance, and prognosis based on long-term observation. Blood 102:4576-4581. doi: 10.1182/blood-2003-02-0613
8. Heimpel H, Schwarz K, Ebnöther M, Goede J, Heydrich D, Kamp T, Plaumann L, Rath B, Roessler J, Schildknecht O, Schmid M, Wuillemin W, Einsiedler B, Leichtle R, Tamary H, Kohne E (2006) Congenital dyserythropoietic anemia type I (CDA I): Molecular genetics, clinical appearance and prognosis based on long-term observation. Blood 107:334-340. doi: 10.1182/blood-2005-01-0421
9. Koch CA, Li CY, Mesa RA, Tefferi A (2003) Nonhepatosplenic extramedullary hematopoiesis: Associated diseases, pathology, clinical course, and treatment. Mayo Clin Proc 78:1223-1233. doi: 10.4065/ 78.10.1223
10. Verani R, Olson J, Moake JL (1980) Intrathoracic extramedullary hematopoiesis: Report of a case in a patient with sickle-cell disease-beta-thalassemia. Am J Clin Pathol 73:133-137
11. Hassoun H, Lawn-Tsao L, Langevin ER Jr, Lathi ES, Palek J (1991) Spinal cord compression secondary to extramedullary hematopoiesis: A noninvasive management based on MRI. Am J Hematol 37:201-203. doi: 10.1002/ajh.2830370314
12. Saghafi M, Shirdel A, Lari SM (2005) Extramedullary hematopoiesis with spinal cord compression in beta-thalassemia intermedia. Eur J Intern Med 16:596-597. doi: 10.1016/j.ejim.2005.04.010
13. Lugassy G, Michaeli J, Harats N, Libson E, Rachmilewitz EA (1986) Paravertebral extramedullary hematopoiesis associated with improvement of anemia in congenital dyserythropoietic anemia type II. Am J Hematol 22:295-300. doi: 10.1002/ajh.2830220310
14. Denzlinger C, Humann M, Steiner W, Bader J, Greither L, Gunther W, Reisbach G, Munker R, Baumgart R, Leeping M et al (1995) 54jährige Patientin mit Anämie, Ikterus, Hepatosplenomegalie und paravertebralen Raumforderungen. Internist (Berl) 36:726-729
15. Herman M, Rocek V, Rehulka M, Indrak K, Gumulec J, Dusek J (1995) Bilateral asymptomatic masses in posterior mediastinum. Intrathoracic extramedullary hematopoiesis. Radiologe 35:297-299
16. Hines GL (1993) Paravertebral extramedullary hematopoiesis (as a posterior mediastinal tumor) associated with congenital dyserythropoietic anemia. J Thorac Cardiovasc Surg 106:760-761
17. Imran A, Mawhinney R, Swirsky D, Hall C (2008) Paravertebral extramedullary haemopoiesis occurring in a case of congenital dyserythropoietic anaemia type II. Br J Haematol 140:1
18. Krouwels FH, Bresser P, von dem Borne EKG (1999) Extramedullary hematopoisis: Breath-taking and hair-raising. N Engl J Med 341:1702-1703. doi: 10.1056/NEJM199911253412219