A charged second-site mutation in the fusion peptide rescues replication of a mutant avian sarcoma and leukosis virus lacking critical cysteine residues flanking the internal fusion domain

Journal of Virology

Volumn 83, Issue 17, 2009, Pages 8575-8586

  Melder, Deborah C ^a   Yin, Xueqian ^a   Delos, Sue E ^b   Federspiel, Mark J ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; HYBRID PROTEIN; MUTANT PROTEIN; OLIGOMER; SERINE; VIRUS GLYCOPROTEIN; AVIAN PROTEIN; TVA RECEPTOR; VIRUS FUSION PROTEIN; VIRUS RECEPTOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; AVIAN SARCOMA VIRUS; CHICKEN; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; FIBROBLAST; GENE REPLICATION; GENETIC VARIABILITY; LEUKEMIA VIRUS; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS; VIRUS GENE; VIRUS INFECTIVITY; VIRUS MUTANT; VIRUS MUTATION; VIRUS REPLICATION; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; GENE REPRESSION; GENETICS; METABOLISM; MISSENSE MUTATION; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN BINDING; VIROLOGY; VIRUS ENTRY;

AVES; EBOLA VIRUS; SUBGROUP A;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; AVIAN PROTEINS; AVIAN SARCOMA VIRUSES; CELLS, CULTURED; CHICKENS; CYSTEINE; FIBROBLASTS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PROTEIN BINDING; RECEPTORS, VIRUS; SUPPRESSION, GENETIC; VIRAL FUSION PROTEINS; VIRUS INTERNALIZATION;

EID: 69249218002     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00526-09     Document Type: Article

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