A novel mutation in a patient with a deficiency of the eighth component of complement associated with recurrent meningococcal meningitis

Journal of Clinical Immunology

Volumn 29, Issue 5, 2009, Pages 691-695

  Arnold, D F ^a   Roberts, A G ^b   Thomas, A ^b   Ferry, B ^a   Morgan, B P ^b   Chapel, H ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Deficiency; Membrane attack complex; Meningitis; Mutation

Indexed keywords

COMPLEMENT COMPONENT C8; COMPLEMENT COMPONENT C8BETA; UNCLASSIFIED DRUG;

ADULT; AMINO ACID SEQUENCE; ARTICLE; CASE REPORT; CAUCASIAN; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; EPIDEMIC MENINGITIS; EXON; FRAMESHIFT MUTATION; GENE DUPLICATION; HETEROZYGOSITY; HUMAN; MALE; MUTATIONAL ANALYSIS; NONSENSE MUTATION; PRIORITY JOURNAL; RECURRENT INFECTION; STOP CODON;

ADOLESCENT; ANTIBIOTIC PROPHYLAXIS; CODON, NONSENSE; COMPLEMENT C8; CYTOTOXICITY, IMMUNOLOGIC; DNA MUTATIONAL ANALYSIS; GENETIC PREDISPOSITION TO DISEASE; HAEMOPHILUS VACCINES; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; IMMUNOTHERAPY; MALE; MENINGITIS, MENINGOCOCCAL; PENICILLINS; PNEUMOCOCCAL VACCINES; RECURRENCE; SEPSIS;

EID: 69249216473     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-009-9295-7     Document Type: Article

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