EGb761 protects hydrogen peroxide-induced death of spinal cord neurons through inhibition of intracellular ROS production and modulation of apoptotic regulating genes

Journal of Molecular Neuroscience

Volumn 38, Issue 2, 2009, Pages 103-113

  Jiang, Xiaoyan ^a,b   Nie, Baoming ^a   Fu, Saili ^a   Hu, Jianguo ^a,c   Yin, Lan ^a   Lin, Lin ^a   Wang, Xiaofei ^a,c   Lu, Peihua ^a   Xu, Xiao Ming ^a,c  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; EGb761; Hydrogen peroxide; Neuroprotection; Oxidative stress; Spinal cord neurons

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; FREE RADICAL; GINKGO BILOBA EXTRACT; HOE 33342; HYDROGEN PEROXIDE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; GINKGO BILOBA EXTRACT 761; NEUROPROTECTIVE AGENT; OXIDIZING AGENT; PLANT EXTRACT;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ISOLATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; EMBRYO; GENE CONTROL; GENE EXPRESSION; GINKGO BILOBA; NERVE CELL NECROSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; RAT; SPINAL CORD INJURY; SPINAL CORD NERVE CELL; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECT; FEMALE; GENETICS; HUMAN; METABOLISM; NERVE CELL; OXIDATION REDUCTION REACTION; PATHOLOGY; PHYSIOLOGY; PREGNANCY; SPINAL CORD; SPRAGUE DAWLEY RAT;

GINKGO BILOBA; RATTUS;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELLS, CULTURED; FEMALE; HUMANS; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; NEURONS; NEUROPROTECTIVE AGENTS; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PLANT EXTRACTS; PREGNANCY; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SPINAL CORD;

EID: 69249215499     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12031-008-9140-0     Document Type: Article

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