Angiogenesis is enhanced by continuous traction in rabbit mandibular distraction osteogenesis

Journal of Cranio-Maxillofacial Surgery

Volumn 37, Issue 7, 2009, Pages 405-411

  Zheng, Li Wu ^a   Ma, Li ^a   Cheung, Lim Kwong ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

angiogenesis; basic fibroblast growth factor; biomechanics; distraction osteogenesis; vascular endothelial growth factor

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; MESSENGER RNA; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE REGENERATION; COMPARATIVE STUDY; CONTROLLED STUDY; DISTRACTION OSTEOGENESIS; GENE EXPRESSION; HISTOLOGY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; NONHUMAN; OSSIFICATION; POSTOPERATIVE PERIOD; RABBIT; REAL TIME POLYMERASE CHAIN REACTION; SURGICAL TECHNIQUE; UPREGULATION;

ANIMALS; BONE REGENERATION; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MANDIBLE; MICROVESSELS; NEOVASCULARIZATION, PHYSIOLOGIC; OSTEOGENESIS, DISTRACTION; RABBITS; RANDOM ALLOCATION; RNA, MESSENGER; TIME FACTORS; TRACTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 69249215217     PISSN: 10105182     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcms.2009.03.007     Document Type: Article

References (41)

1. Ai-Aql Z.S., Alagl A.S., Graves D.T., Gerstenfeld L.C., and Einhorn T.A. Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis. J Dent Res 87 (2008) 107-118
2. Ayoub A.F., and Richardson W. A new device for micro incremental automatic distraction osteogenesis. Br J Oral Maxillofac Surg 39 (2001) 353-355
3. Barnes G.L., Kostenuik P.J., Gerstenfeld L.C., and Einhorn T.A. Growth factor regulation of fracture repair. J Bone Miner Res 14 (1999) 1805-1815
4. Bikfalvi A., Klein S., Pintucci G., and Rifkin D.B. Biological roles of fibroblast growth factor-2. Endocr Rev 18 (1997) 26-45
5. Byun J.H., Park B.W., Kim J.R., and Lee J.H. Expression of vascular endothelial growth factor and its receptors after mandibular distraction osteogenesis. Int J Oral Maxillofac Surg 36 (2007) 338-344
6. Carvalho R.S., Einhorn T.A., Lehmann W., Edgar C., Al-Yamani A., Apazidis A., Pacicca D., Clemens T.L., and Gerstenfeld L.C. The role of angiogenesis in a murine tibial model of distraction osteogenesis. Bone 34 (2004) 849-861
7. Cheung L.K., Zheng L.W., and Ma L. Effect of distraction rates on expression of bone morphogenetic proteins in rabbit mandibular distraction osteogenesis. J Craniomaxillofac Surg 34 (2006) 263-269
8. Fang T.D., Salim A., Xia W., Nacamuli R.P., Guccione S., Song H.M., Carano R.A., Filvaroff E.H., Bednarski M.D., Giaccia A.J., and Longaker M.T. Angiogenesis is required for successful bone induction during distraction osteogenesis. J Bone Miner Res 20 (2005) 1114-1124
9. Greenwald J.A., Luchs J.S., Mehrara B.J., Spector J.A., Mackool R.J., McCarthy J.G., and Longaker M.T. Pumping the regenerate: an evaluation of oscillating distraction osteogenesis in the rodent mandible. Ann Plast Surg 44 (2000) 516-521
10. Hu J., Zou S., Li J., Chen Y., Wang D., and Gao Z. Temporospatial expression of vascular endothelial growth factor and basic fibroblast growth factor during mandibular distraction osteogenesis. J Craniomaxillofac Surg 31 (2003) 238-243
11. Ilizarov G.A. The tension-stress effect on the genesis and growth of tissues: part II. The influence of the rate and frequency of distraction. Clin Orthop 239 (1989) 263-285
12. Isaksson H., Comas O., van Donkelaar C.C., Mediavilla J., Wilson W., Huiskes R., and Ito K. Bone regeneration during distraction osteogenesis: mechano-regulation by shear strain and fluid velocity. J Biomech 40 (2007) 2002-2011
13. Jacobsen K.A., Al-Aql Z.S., Wan C., Fitch J.L., Stapleton S.N., Mason Z.D., Cole R.M., Gilbert S.R., Clemens T.L., Morgan E.F., Einhorn T.A., and Gerstenfeld L.C. Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling. J Bone Miner Res 23 (2008) 596-609
14. Kessler P.A., Merten H.A., Neukam F.W., and Wiltfang J. The effects of magnitude and frequency of distraction forces on tissue regeneration in distraction osteogenesis of the mandible. Plast Reconstr Surg 109 (2002) 171-180
15. Kessler P., Neukam F.W., and Wiltfang J. Effects of distraction forces and frequency of distraction on bony regeneration. Br J Oral Maxillofac Surg 43 (2005) 392-398
16. Leung D.W., Cachianes G., Kuang W.J., Goeddel D.V., and Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246 (1989) 1306-1309
17. Linde A., and Hedner E. Recombinant bone morphogenetic protein-2 enhances bone healing, guided by osteopromotive e-PTFE membranes: an experimental study in rats. Calcif Tissue Int 56 (1995) 549-553
18. Li G., Simpson A.H., Kenwright J., and Triffitt J.T. Effect of lengthening rate on angiogenesis during distraction osteogenesis. J Orthop Res 17 (1999) 362-367
19. Li G., Simpson A.H., Kenwright J., and Triffitt J.T. Assessment of cell proliferation in regenerating bone during distraction osteogenesis at different distraction rates. J Orthop Res 15 (1997) 765-772
20. Loboa E.G., Fang T.D., Warren S.M., Lindsey D.P., Fong K.D., Longaker M.T., and Carter D.R. Mechanobiology of mandibular distraction osteogenesis: experimental analyses with a rat model. Bone 34 (2004) 336-343
21. Pacicca D.M., Patel N., Lee C., Salisbury K., Lehmann W., Carvalho R., Gerstenfeld L.C., and Einhorn T.A. Expression of angiogenic factors during distraction osteogenesis. Bone 33 (2003) 889-898
22. Paccione M.F., Mehrara B.J., Warren S.M., Greenwald J.A., Spector J.A., Luchs J.S., and Longaker M.T. Rat mandibular distraction osteogenesis: latency, rate, and rhythm determine the adaptive response. J Craniofac Surg 12 (2001) 175-182
23. Ploder O., Mayr W., Schnetz G., Unger E., Ewers R., and Plenk Jr. H. Mandibular lengthening with an implanted motor-driven device: preliminary study in sheep. Br J Oral Maxillofac Surg 37 (1996) 273-276
24. Pollock G.A., McKelvie P.A., McCarty D.J., White J.F., Mallari P.L., and Taylor H.R. In vivo effects of fluoroquinolones on rabbit corneas. Clin Experiment Ophthalmol 31 (2003) 517-521
25. Rowe N.M., Mehrara B.J., Luchs J.S., Dudziak M.E., Steinbrech D.S., Illei P.B., Fernandez G.J., Gittes G.K., and Longaker M.T. Angiogenesis during mandibular distraction osteogenesis. Ann Plast Surg 42 (1999) 470-475
26. Richardson T.P., Peters M.C., Ennett A.B., and Mooney D.J. Polymeric system for dual growth factor delivery. Nat Biotechnol 19 (2001) 1029-1034
27. al Ruhaimi K.A. Comparison of different distraction rates in the mandible: an experimental investigation. Int J Oral Maxillofac Surg 30 (2001) 220-227
28. Schiller J.R., Moore D.C., and Ehrlich M.G. Increased lengthening rate decreases expression of fibroblast growth factor 2, platelet-derived growth factor, vascular endothelial growth factor, and CD31 in a rat model of distraction osteogenesis. J Pediatr Orthop 27 (2007) 961-968
29. Schmelzeisen R., Neumann G., and von der Fecht R. Distraction osteogenesis in the mandible with a motor driven plate: a preliminary animal study. Br J Oral Maxillofac Surg 34 (1996) 375-378
30. Seghezzi G., Patel S., Ren C.J., Gualandris A., Pintucci G., Robbins E.S., Shapiro R.L., Galloway A.C., Rifkin D.B., and Mignatti P. Fibroblast growth factor-2 induces vascular endothelial growth factor expression in the endothelial cells of forming capillaries: an autocrine mechanism contributing to angiogenesis. J Cell Biol 141 (1998) 1659-1673
31. Shweiki D., Itin A., Neufeld G., Gitay-Goren H., and Keshet E. Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis. J Clin Invest 91 (1993) 2235-2243
32. Stewart K.J., Lvoff G.O., White S.A., Bonar S.F., Walsh W.R., Smart R.C., and Poole M.D. Mandibular distraction osteogenesis: a comparison of distraction rates in the rabbit model. J Craniomaxillofac Surg 26 (1998) 43-49
33. Waanders N.A., Richards M., Steen H., Kuhn J.L., Goldstein S.A., and Goulet J.A. Evaluation of the mechanical environment during distraction osteogenesis. Clin Orthop Relat Res 349 (1998) 225-234
34. Warren S.M., Mehrara B.J., Steinbrech D.S., Paccione M.F., Greenwald J.A., Spector J.A., and Longaker M.T. Rat mandibular distraction osteogenesis: part III. Gradual distraction versus acute lengthening. Plast Reconstr Surg 107 (2001) 441-453
35. Weiss S., Baumgart R., Jochum M., Strasburger C.J., and Bidlingmaier M. Systemic regulation of distraction osteogenesis: a cascade of biochemical factors. J Bone Miner Res 17 (2002) 1280-1289
36. Wiltfang J., Kessler P., Merten H.A., and Neukam F.W. Continuous and intermittent bone traction using microhydraulic cylinder: an experimental study in minipigs. Br J Oral Maxillofac Surg 39 (2001) 2-7
37. Zelzer E., Mamluk R., Ferrara N., Johnson R.S., Schipani E., and Olsen B.R. VEGFA is necessary for chondrocyte survival during bone development. Development 131 (2004) 2161-2171
38. Zelzer E., and Olsen B.R. Multiple roles of vascular endothelial growth factor in skeletal development, growth, and repair. Curr Top Dev Biol 65 (2005) 169-187
39. Zheng L.W., and Cheung L.K. Effect of recombinant human bone morphogenetic protein-2 on mandibular distraction at different rates. Tissue Eng 12 (2006) 3181-3188
40. Zheng L.W., Cheung L.K., Ma L., and Wong M.C. High rhythm automatic driver for bone traction: an experimental study in rabbits. Int J Oral Maxillofac Surg 37 (2008) 736-740
41. Zheng L.W., Ma L., and Cheung L.K. Changes in blood perfusion and bone healing induced by nicotine during distraction osteogenesis. Bone 43 (2008) 355-361