Clinical application of cytokine-related gene polymorphism analysis using a newly developed DNA chip in critically ill patients

Clinical Biochemistry

Volumn 42, Issue 13-14, 2009, Pages 1387-1393

  Otani, Shunsuke ^a   Oda, Shigeto ^a   Sadahiro, Tomohito ^a   Nakamura, Masataka ^a   Watanabe, Eizo ^a   Nakada, Taka aki ^a   Abe, Ryuzo ^a   Tokuhisa, Takeshi ^b   Hirasawa, Hiroyuki ^a  

^a CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b CHIBA UNIVERSITY   (Japan)

Author keywords

Critical care; Cytokine; DNA chip; Single base extension (SBE); Single nucleotide polymorphism (SNP); Tailor made medicine; TaqMan method

Indexed keywords

CYTOKINE; GENOMIC DNA; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CRITICAL ILLNESS; DNA EXTRACTION; DNA MICROARRAY; DNA SEQUENCE; GENOTYPE; HOSPITAL ADMISSION; HUMAN; HYBRIDIZATION; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; VALIDATION PROCESS;

CRITICAL ILLNESS; DNA MUTATIONAL ANALYSIS; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTENSIVE CARE UNITS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MICROARRAY ANALYSIS; NUCLEIC ACID HYBRIDIZATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; REPRODUCIBILITY OF RESULTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 69249215195     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2009.06.005     Document Type: Article

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