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Volumn 36, Issue 7, 2009, Pages 811-819

In vivo monitoring of intranuclear p27kip1 protein expression in breast cancer cells during trastuzumab (Herceptin) therapy

Author keywords

Herceptin; Nuclear, p27kip1; Radioimmunoconjugates; Tat

Indexed keywords

ANTIBODY CONJUGATE; CARBOHYDRATE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 1B ANTIBODY TAT PEPTIDE PENTETATE INDIUM IN 111; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G TAT IN 111; INDIUM 111; PENTETATE INDIUM IN 111; PENTETIC ACID; PEPTIDE; PERIODATE SODIUM; PROTEIN ANTIBODY; RADIOPHARMACEUTICAL AGENT; SCHIFF BASE; SODIUM CHLORIDE; TRASTUZUMAB; UNCLASSIFIED DRUG;

EID: 69249205433     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2009.05.003     Document Type: Article
Times cited : (10)

References (38)
  • 2
    • 0012890297 scopus 로고    scopus 로고
    • Fornier M, Risio M, Van Poznak C, Seidman A. HER2 testing and correlation with efficacy of trastuzumab therapy. Oncology (Huntingt) 2002;16:1340-8, 51-2. [discussion 52, 55-8].
    • Fornier M, Risio M, Van Poznak C, Seidman A. HER2 testing and correlation with efficacy of trastuzumab therapy. Oncology (Huntingt) 2002;16:1340-8, 51-2. [discussion 52, 55-8].
  • 3
    • 0036274024 scopus 로고    scopus 로고
    • c-erbB-2 in breast cancer: development of a clinically useful marker
    • Hayes D.F., and Thor A.D. c-erbB-2 in breast cancer: development of a clinically useful marker. Semin Oncol 29 (2002) 231-245
    • (2002) Semin Oncol , vol.29 , pp. 231-245
    • Hayes, D.F.1    Thor, A.D.2
  • 4
    • 0242694519 scopus 로고    scopus 로고
    • HER-2-targeted therapy: lessons learned and future directions
    • Nahta R., and Esteva F.J. HER-2-targeted therapy: lessons learned and future directions. Clin Cancer Res 9 (2003) 5078-5084
    • (2003) Clin Cancer Res , vol.9 , pp. 5078-5084
    • Nahta, R.1    Esteva, F.J.2
  • 5
    • 37049183697 scopus 로고
    • Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon D.J., Clark G.M., Wong S.G., Levin W.J., Ullrich A., and McGuire W.L. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Sciences (New York) 235 (1987) 177-182
    • (1987) Sciences (New York) , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 6
    • 0346338203 scopus 로고    scopus 로고
    • Combining trastuzumab (Herceptin) with hormonal therapy in breast cancer: what can be expected and why?
    • Jones A. Combining trastuzumab (Herceptin) with hormonal therapy in breast cancer: what can be expected and why?. Ann Oncol 14 (2003) 1697-1704
    • (2003) Ann Oncol , vol.14 , pp. 1697-1704
    • Jones, A.1
  • 7
    • 0034638925 scopus 로고    scopus 로고
    • Molecular mechanisms underlying ErbB2/HER2 action in breast cancer
    • Harari D., and Yarden Y. Molecular mechanisms underlying ErbB2/HER2 action in breast cancer. Oncogene 19 (2000) 6102-6114
    • (2000) Oncogene , vol.19 , pp. 6102-6114
    • Harari, D.1    Yarden, Y.2
  • 8
    • 33745986327 scopus 로고    scopus 로고
    • HER2 testing by local, central, and reference laboratories in specimens from the North Central Cancer Treatment Group N9831 intergroup adjuvant trial
    • Perez E.A., Suman V.J., Davidson N.E., Martino S., Kaufman P.A., Lingle W.L., et al. HER2 testing by local, central, and reference laboratories in specimens from the North Central Cancer Treatment Group N9831 intergroup adjuvant trial. J Clin Oncol 24 (2006) 3032-3038
    • (2006) J Clin Oncol , vol.24 , pp. 3032-3038
    • Perez, E.A.1    Suman, V.J.2    Davidson, N.E.3    Martino, S.4    Kaufman, P.A.5    Lingle, W.L.6
  • 9
    • 0035915283 scopus 로고    scopus 로고
    • Unraveling resistance to trastuzumab (Herceptin): insulin-like growth factor-I receptor, a new suspect
    • Albanell J., and Baselga J. Unraveling resistance to trastuzumab (Herceptin): insulin-like growth factor-I receptor, a new suspect. J Natl Cancer Inst 93 (2001) 1830-1832
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1830-1832
    • Albanell, J.1    Baselga, J.2
  • 10
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • Cobleigh M.A., Vogel C.L., Tripathy D., Robert N.J., Scholl S., Fehrenbacher L., et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 17 (1999) 2639-2648
    • (1999) J Clin Oncol , vol.17 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3    Robert, N.J.4    Scholl, S.5    Fehrenbacher, L.6
  • 11
    • 0242721899 scopus 로고    scopus 로고
    • Clinical experience with trastuzumab (Herceptin)
    • Vogel C.L., and Franco S.X. Clinical experience with trastuzumab (Herceptin). Breast J 9 (2003) 452-462
    • (2003) Breast J , vol.9 , pp. 452-462
    • Vogel, C.L.1    Franco, S.X.2
  • 12
    • 0033996361 scopus 로고    scopus 로고
    • ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency
    • Lane H.A., Beuvink I., Motoyama A.B., Daly J.M., Neve R.M., and Hynes N.E. ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency. Mol Cell Biol 20 (2000) 3210-3223
    • (2000) Mol Cell Biol , vol.20 , pp. 3210-3223
    • Lane, H.A.1    Beuvink, I.2    Motoyama, A.B.3    Daly, J.M.4    Neve, R.M.5    Hynes, N.E.6
  • 13
    • 0033965065 scopus 로고    scopus 로고
    • Anti-HER2 antibody and heregulin suppress growth of HER2-overexpressing human breast cancer cells through different mechanisms
    • Le X.F., McWatters A., Wiener J., Wu J.Y., Mills G.B., and Bast Jr. R.C. Anti-HER2 antibody and heregulin suppress growth of HER2-overexpressing human breast cancer cells through different mechanisms. Clin Cancer Res 6 (2000) 260-270
    • (2000) Clin Cancer Res , vol.6 , pp. 260-270
    • Le, X.F.1    McWatters, A.2    Wiener, J.3    Wu, J.Y.4    Mills, G.B.5    Bast Jr., R.C.6
  • 14
    • 0037099532 scopus 로고    scopus 로고
    • Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action
    • Yakes F.M., Chinratanalab W., Ritter C.A., King W., Seelig S., and Arteaga C.L. Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action. Cancer Res 62 (2002) 4132-4141
    • (2002) Cancer Res , vol.62 , pp. 4132-4141
    • Yakes, F.M.1    Chinratanalab, W.2    Ritter, C.A.3    King, W.4    Seelig, S.5    Arteaga, C.L.6
  • 15
    • 6344270303 scopus 로고    scopus 로고
    • Enhancement of the p27Kip1-mediated antiproliferative effect of trastuzumab (Herceptin) on HER2-overexpressing tumor cells
    • Marches R., and Uhr J.W. Enhancement of the p27Kip1-mediated antiproliferative effect of trastuzumab (Herceptin) on HER2-overexpressing tumor cells. Int J Cancer 112 (2004) 492-501
    • (2004) Int J Cancer , vol.112 , pp. 492-501
    • Marches, R.1    Uhr, J.W.2
  • 16
    • 2542526069 scopus 로고    scopus 로고
    • P27(kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells
    • Nahta R., Takahashi T., Ueno N.T., Hung M.C., and Esteva F.J. P27(kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells. Cancer Res 64 (2004) 3981-3986
    • (2004) Cancer Res , vol.64 , pp. 3981-3986
    • Nahta, R.1    Takahashi, T.2    Ueno, N.T.3    Hung, M.C.4    Esteva, F.J.5
  • 17
    • 41149150219 scopus 로고    scopus 로고
    • The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy
    • Chu I.M., Hengst L., and Slingerland J.M. The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nat Rev 8 (2008) 253-267
    • (2008) Nat Rev , vol.8 , pp. 253-267
    • Chu, I.M.1    Hengst, L.2    Slingerland, J.M.3
  • 18
    • 19644389497 scopus 로고    scopus 로고
    • Tumor suppressor VDUP1 increases p27(kip1) stability by inhibiting JAB1
    • Jeon J.H., Lee K.N., Hwang C.Y., Kwon K.S., You K.H., and Choi I. Tumor suppressor VDUP1 increases p27(kip1) stability by inhibiting JAB1. Cancer Res 65 (2005) 4485-4489
    • (2005) Cancer Res , vol.65 , pp. 4485-4489
    • Jeon, J.H.1    Lee, K.N.2    Hwang, C.Y.3    Kwon, K.S.4    You, K.H.5    Choi, I.6
  • 19
    • 39749174303 scopus 로고    scopus 로고
    • Peptide motifs for insertion of radiolabeled biomolecules into cells and routing to the nucleus for cancer imaging or radiotherapeutic applications
    • Costantini D.L., Hu M., and Reilly R.M. Peptide motifs for insertion of radiolabeled biomolecules into cells and routing to the nucleus for cancer imaging or radiotherapeutic applications. Cancer Biother Radiopharm 23 (2008) 3-24
    • (2008) Cancer Biother Radiopharm , vol.23 , pp. 3-24
    • Costantini, D.L.1    Hu, M.2    Reilly, R.M.3
  • 20
    • 52949148197 scopus 로고    scopus 로고
    • Cell penetrating peptides for in vivo molecular imaging applications
    • Kersemans V., Kersemans K., and Cornelissen B. Cell penetrating peptides for in vivo molecular imaging applications. Curr Pharm Des 14 (2008) 2415-2447
    • (2008) Curr Pharm Des , vol.14 , pp. 2415-2447
    • Kersemans, V.1    Kersemans, K.2    Cornelissen, B.3
  • 22
    • 37349013170 scopus 로고    scopus 로고
    • Properties of [(111)In]-labeled HIV-1 tat peptide radioimmunoconjugates in tumor-bearing mice following intravenous or intratumoral injection
    • Cornelissen B., McLarty K., Kersemans V., Scollard D.A., and Reilly R.M. Properties of [(111)In]-labeled HIV-1 tat peptide radioimmunoconjugates in tumor-bearing mice following intravenous or intratumoral injection. Nucl Med Biol 35 (2008) 101-110
    • (2008) Nucl Med Biol , vol.35 , pp. 101-110
    • Cornelissen, B.1    McLarty, K.2    Kersemans, V.3    Scollard, D.A.4    Reilly, R.M.5
  • 23
    • 33644970478 scopus 로고    scopus 로고
    • Site-specific conjugation of HIV-1 tat peptides to IgG: a potential route to construct radioimmunoconjugates for targeting intracellular and nuclear epitopes in cancer
    • Hu M., Chen P., Wang J., Chan C., Scollard D.A., and Reilly R.M. Site-specific conjugation of HIV-1 tat peptides to IgG: a potential route to construct radioimmunoconjugates for targeting intracellular and nuclear epitopes in cancer. Eur J Nucl Med Mol Imaging 33 (2006) 301-310
    • (2006) Eur J Nucl Med Mol Imaging , vol.33 , pp. 301-310
    • Hu, M.1    Chen, P.2    Wang, J.3    Chan, C.4    Scollard, D.A.5    Reilly, R.M.6
  • 24
    • 33847105943 scopus 로고    scopus 로고
    • 123I-labeled HIV-1 tat peptide radioimmunoconjugates are imported into the nucleus of human breast cancer cells and functionally interact in vitro and in vivo with the cyclin-dependent kinase inhibitor, p21(WAF-1/Cip-1)
    • 123I-labeled HIV-1 tat peptide radioimmunoconjugates are imported into the nucleus of human breast cancer cells and functionally interact in vitro and in vivo with the cyclin-dependent kinase inhibitor, p21(WAF-1/Cip-1). Eur J Nucl Med Mol Imaging 34 (2007) 368-377
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , pp. 368-377
    • Hu, M.1    Chen, P.2    Wang, J.3    Scollard, D.A.4    Vallis, K.A.5    Reilly, R.M.6
  • 25
    • 33749005950 scopus 로고    scopus 로고
    • HIV-1 Tat peptide immunoconjugates differentially sensitize breast cancer cells to selected antiproliferative agents that induce the cyclin-dependent kinase inhibitor p21WAF-1/CIP-1
    • Hu M., Wang J., Chen P., and Reilly R.M. HIV-1 Tat peptide immunoconjugates differentially sensitize breast cancer cells to selected antiproliferative agents that induce the cyclin-dependent kinase inhibitor p21WAF-1/CIP-1. Bioconjug Chem 17 (2006) 1280-1287
    • (2006) Bioconjug Chem , vol.17 , pp. 1280-1287
    • Hu, M.1    Wang, J.2    Chen, P.3    Reilly, R.M.4
  • 26
    • 0017874586 scopus 로고
    • Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril
    • Fraker P.J., and Speck Jr. J.C. Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril. Biochem Biophys Res Commun 80 (1978) 849-857
    • (1978) Biochem Biophys Res Commun , vol.80 , pp. 849-857
    • Fraker, P.J.1    Speck Jr., J.C.2
  • 27
    • 0032780931 scopus 로고    scopus 로고
    • Elevated levels of p27, p21 and cyclin D1 correlate with positive oestrogen and progesterone receptor status in node-negative breast carcinoma patients
    • Reed W., Florems V.A., Holm R., Hannisdal E., and Nesland J.M. Elevated levels of p27, p21 and cyclin D1 correlate with positive oestrogen and progesterone receptor status in node-negative breast carcinoma patients. Virchows Arch 435 (1999) 116-124
    • (1999) Virchows Arch , vol.435 , pp. 116-124
    • Reed, W.1    Florems, V.A.2    Holm, R.3    Hannisdal, E.4    Nesland, J.M.5
  • 28
    • 0032723348 scopus 로고    scopus 로고
    • Lack of independent prognostic significance of p21 and p27 expression in advanced ovarian cancer: an immunohistochemical study
    • Baekelandt M., Holm R., Trope C.G., Nesland J.M., and Kristensen G.B. Lack of independent prognostic significance of p21 and p27 expression in advanced ovarian cancer: an immunohistochemical study. Clin Cancer Res 5 (1999) 2848-2853
    • (1999) Clin Cancer Res , vol.5 , pp. 2848-2853
    • Baekelandt, M.1    Holm, R.2    Trope, C.G.3    Nesland, J.M.4    Kristensen, G.B.5
  • 29
    • 34547786032 scopus 로고    scopus 로고
    • (111)In-labeled trastuzumab (Herceptin) modified with nuclear localization sequences (NLS): an Auger electron-emitting radiotherapeutic agent for HER2/neu-amplified breast cancer
    • Costantini D.L., Chan C., Cai Z., Vallis K.A., and Reilly R.M. (111)In-labeled trastuzumab (Herceptin) modified with nuclear localization sequences (NLS): an Auger electron-emitting radiotherapeutic agent for HER2/neu-amplified breast cancer. J Nucl Med 48 (2007) 1357-1368
    • (2007) J Nucl Med , vol.48 , pp. 1357-1368
    • Costantini, D.L.1    Chan, C.2    Cai, Z.3    Vallis, K.A.4    Reilly, R.M.5
  • 30
    • 0035203632 scopus 로고    scopus 로고
    • Transport into and out of the nucleus
    • table of contents
    • Macara I.G. Transport into and out of the nucleus. Microbiol Mol Biol Rev 65 (2001) 570-594 table of contents
    • (2001) Microbiol Mol Biol Rev , vol.65 , pp. 570-594
    • Macara, I.G.1
  • 31
    • 66249108561 scopus 로고    scopus 로고
    • 111In-Labeled immunoconjugates (ICs) bispecific for the epidermal growth factor receptor (EGFR) and cyclin-dependent kinase inhibitor, p27Kip1
    • in press
    • 111In-Labeled immunoconjugates (ICs) bispecific for the epidermal growth factor receptor (EGFR) and cyclin-dependent kinase inhibitor, p27Kip1. Cancer Biother Radiopharm (2009) in press
    • (2009) Cancer Biother Radiopharm
    • Cornelissen, B.1    Kersemans, V.2    McLarty, K.3    Tran, L.4    Reilly, R.M.5
  • 34
    • 33846468746 scopus 로고    scopus 로고
    • Potentiation of antitumour activity of docetaxel by combination with trastuzumab in a human prostate cancer xenograft model and underlying mechanisms
    • Legrier M.E., Oudard S., Judde J.G., Guyader C., de Pinieux G., Boye K., et al. Potentiation of antitumour activity of docetaxel by combination with trastuzumab in a human prostate cancer xenograft model and underlying mechanisms. Br J Cancer 96 (2007) 269-276
    • (2007) Br J Cancer , vol.96 , pp. 269-276
    • Legrier, M.E.1    Oudard, S.2    Judde, J.G.3    Guyader, C.4    de Pinieux, G.5    Boye, K.6
  • 35
    • 69249242441 scopus 로고    scopus 로고
    • ZD1839 (Iressa™) sensitivity is regulated through a p27-dependent mechanism in bladder cancer cells
    • Shrader M., Pino M.S., and McConkey D. ZD1839 (Iressa™) sensitivity is regulated through a p27-dependent mechanism in bladder cancer cells. AACR Meeting Abstracts (2005) 802
    • (2005) AACR Meeting Abstracts , pp. 802
    • Shrader, M.1    Pino, M.S.2    McConkey, D.3
  • 36
    • 0345096611 scopus 로고    scopus 로고
    • Gefitinib ('Iressa', ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, up-regulates p27KIP1 and induces G1 arrest in oral squamous cell carcinoma cell lines
    • Shintani S., Li C., Mihara M., Yano J., Terakado N., Nakashiro K., et al. Gefitinib ('Iressa', ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, up-regulates p27KIP1 and induces G1 arrest in oral squamous cell carcinoma cell lines. Oral oncology 40 (2004) 43-51
    • (2004) Oral oncology , vol.40 , pp. 43-51
    • Shintani, S.1    Li, C.2    Mihara, M.3    Yano, J.4    Terakado, N.5    Nakashiro, K.6
  • 37
    • 33747635920 scopus 로고    scopus 로고
    • Somatostatin analogues stimulate p27 expression and inhibit the MAP kinase pathway in pituitary tumours
    • Hubina E., Nanzer A.M., Hanson M.R., Ciccarelli E., Losa M., Gaia D., et al. Somatostatin analogues stimulate p27 expression and inhibit the MAP kinase pathway in pituitary tumours. Eur J Endocrinol 155 (2006) 371-379
    • (2006) Eur J Endocrinol , vol.155 , pp. 371-379
    • Hubina, E.1    Nanzer, A.M.2    Hanson, M.R.3    Ciccarelli, E.4    Losa, M.5    Gaia, D.6
  • 38
    • 16644400993 scopus 로고    scopus 로고
    • Expression of p27 in residual rectal cancer after preoperative chemoradiation predicts long-term outcome
    • Moore H.G., Shia J., Klimstra D.S., Ruo L., Mazumdar M., Schwartz G.K., et al. Expression of p27 in residual rectal cancer after preoperative chemoradiation predicts long-term outcome. Ann Surg Oncol 11 (2004) 955-961
    • (2004) Ann Surg Oncol , vol.11 , pp. 955-961
    • Moore, H.G.1    Shia, J.2    Klimstra, D.S.3    Ruo, L.4    Mazumdar, M.5    Schwartz, G.K.6


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