Clinical applications of FDG PET and PET/CT in head and neck cancer

Journal of Oncology

Volumn , Issue , 2009, Pages

  Al Ibraheem, Akram ^a   Buck, Andreas ^a   Krause, Bernd Joachim ^a   Scheidhauer, Klemens ^a   Schwaiger, Markus ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 FLUORO 3 (2 NITRO 1 IMIDAZOLYL) 2 PROPANOL F 18; 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID CETUXIMAB CU 64; 2 (2 NITRO 1H IMIDAZOL 1 YL) N (2,2,3,3,3 PENTAFLUOROPROPYL)ACETAMIDE; 3 DEOXY 3 FLUOROTHYMIDINE F 18; ARGINYLGLYCYLASPARTIC ACID; CETUXIMAB; COPPER 60; COPPER 64; COPPER COMPLEX; COPPER DIACETYLBIS(N4 METHYLTHIOSEMICARBAZONE) CU 60; EPIDERMAL GROWTH FACTOR RECEPTOR; FLUORINE 18; FLUOROAZOMYCIN ARABINOSIDE F 18; FLUORODEOXYGLUCOSE F 18; MONOCLONAL ANTIBODY; RADIOPHARMACEUTICAL AGENT; THIOSEMICARBAZONE DERIVATIVE; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANGIOGENESIS; CANCER DIAGNOSIS; CANCER OF UNKNOWN PRIMARY SITE; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTRAST ENHANCEMENT; DIAGNOSTIC ACCURACY; DRUG TARGETING; DRUG UPTAKE; EARLY DIAGNOSIS; HEAD AND NECK CANCER; HUMAN; HYPOPHARYNX CANCER; HYPOXIA; INTENSITY MODULATED RADIATION THERAPY; INTERMETHOD COMPARISON; ISOTOPE LABELING; LYMPH NODE METASTASIS; METASTASIS; MOLECULAR IMAGING; MOUTH CANCER; MULTIDETECTOR COMPUTED TOMOGRAPHY; NASOPHARYNX CANCER; NUCLEAR MAGNETIC RESONANCE IMAGING; OROPHARYNX CANCER; POSITRON EMISSION TOMOGRAPHY; PREDICTION; PREOPERATIVE EVALUATION; PRIMARY TUMOR; PROGNOSIS; REVIEW; SECOND CANCER; SPIRAL COMPUTER ASSISTED TOMOGRAPHY; SQUAMOUS CELL CARCINOMA; TREATMENT PLANNING; TREATMENT RESPONSE;

EID: 69249203592     PISSN: 16878450     EISSN: 16878469     Source Type: Journal    
DOI: 10.1155/2009/208725     Document Type: Review

References (108)

1. Jemal A., Siegel R., Ward E., Cancer statistics, 2008 CA: Cancer Journal for Clinicians 2008 58 2 71 96
2. Baek C.-H., Chung M. K., Jeong H.-S., The clinical usefulness of 18F-FDG PET/CT for the evaluation of lymph node metastasis in periorbital malignancies Korean Journal of Radiology 2009 10 1 1 7
3. Roh J.-L., Yeo N.-K., Kim J. S., Utility of 2-[18F] fluoro-2-deoxy-d- glucose positron emission tomography and positron emission tomography/computed tomography imaging in the preoperative staging of head and neck squamous cell carcinoma Oral Oncology 2007 43 9 887 893
4. Gordin A., Golz A., Daitzchman M., Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography imaging in patients with carcinoma of the nasopharynx: diagnostic accuracy and impact on clinical management International Journal of Radiation Oncology Biology Physics 2007 68 2 370 376
5. Kim M. R., Roh J.-L., Kim J. S., Utility of 18F-fluorodeoxyglucose positron emission tomography in the preoperative staging of squamous cell carcinoma of the oropharynx European Journal of Surgical Oncology 2007 33 5 633 638
6. Dammann F., Horger M., Mueller-Berg M., Rational diagnosis of squamous cell carcinoma of the head and neck region: comparative evaluation of CT, MRI, and 18FDG PET American Journal of Roentgenology 2005 184 4 1326 1331
7. Ng S.-H., Yen T.-C., Liao C.-T., 18F-FDG PET and CT/MRI in oral cavity squamous cell carcinoma: a prospective study of 124 patients with histologic correlation Journal of Nuclear Medicine 2005 46 7 1136 1143
8. Valk P. E., Pounds T. R., Tesar R. D., Hopkins D. M., Haseman M. K., Cost-effectiveness of PET imaging in clinical oncology Nuclear Medicine and Biology 1996 23 6 737 743
9. Scarfone C., Lavely W. C., Cmelak A. J., Prospective feasibility trial of radiotherapy target definition for head and neck cancer using 3-dimensional PET and CT imaging Journal of Nuclear Medicine 2004 45 4 543 552
10. Ha P. K., Hdeib A., Goldenberg D., The role of positron emission tomography and computed tomography fusion in the management of early-stage and advanced-stage primary head and neck squamous cell carcinoma Archives of Otolaryngology 2006 132 1 12 16
11. Gordin A., Daitzchman M., Doweck I., Fluorodeoxyglucose-positron emission tomography/computed tomography imaging in patients with carcinoma of the larynx: diagnostic accuracy and impact on clinical management Laryngoscope 2006 116 2 273 278
12. Goerres G. W., Schmid D. T., Gratz K. W., Von Schulthess G. K., Eyrich G. K., Impact of whole body positron emission tomography on initial staging and therapy in patients with squamous cell carcinoma of the oral cavity Oral Oncology 2003 39 6 547 551
13. Schmid D. T., Stoeckli S. J., Bandhauer F., Impact of positron emission tomography on the initial staging and therapy in locoregional advanced squamous cell carcinoma of the head and neck Laryngoscope 2003 113 5 888 891
14. Stokkel M. P., ten Broek F.-W., Hordijk G.-J., Koole R., van Rijk P. P., Preoperative evaluation of patients with primary head and neck cancer using dual-head 18fluorodeoxyglucose positron emission tomography Annals of Surgery 2000 231 2 229 234
15. Branstetter B. F. T. IV, Blodgett T. M., Zimmer L. A., Head and neck malignancy: is PET/CT more accurate than PET or CT alone? Radiology 2005 235 2 580 586
16. Schoder H., Yeung H. W., Gonen M., Kraus D., Larson S. M., Head and neck cancer: clinical usefulness and accuracy of PET/CT image fusion Radiology 2004 231 1 65 72
17. Syed R., Bomanji J. B., Nagabhushan N., Impact of combined 18F-FDG PET/CT in head and neck tumours British Journal of Cancer 2005 92 6 1046 1050
18. Hannah A., Scott A. M., Tochon-Danguy H., Evaluation of 18F-fluorodeoxyglucose positron emission tomography and computed tomography with histopathologic correlation in the initial staging of head and neck cancer Annals of Surgery 2002 236 2 208 217
19. Ng S.-H., Yen T.-C., Chang J.T., Prospective study of [18F]fluorodeoxyglucose positron emission tomography and computed tomography and magnetic resonance imaging in oral cavity squamous cell carcinoma with palpably negative neck Journal of Clinical Oncology 2006 24 27 4371 4376
20. Baek C.-H., Chung M. K., Son Y.-I., Tumor volume assessment by 18F-FDG PET/CT in patients with oral cavity cancer with dental artifacts on CT or MR images Journal of Nuclear Medicine 2008 49 9 1422 1428
21. Mendenhall W., Morris C., Hinerman R., Malyapa R. S., Amdur R. J., Definitive radiotherapy for nasopharyngeal carcinoma American Journal of Clinical Oncology 2006 29 6 622 627
22. Adams S., Baum R. P., Stuckensen T., Bitter K., Hr G., Prospective comparison of 18F-FDG PET with conventional imaging modalities (CT, MRI, US) in lymph node staging of head and neck cancer European Journal of Nuclear Medicine 1998 25 9 1255 1260
23. Zhuang H., Kumar R., Mandel S., Alavi A., Investigation of thyroid, head, and neck cancers with PET Radiologic Clinics of North America 2004 42 6 1101 1111
24. Quon A., Fischbein N. J., McDougall I. R., Clinical role of 18F-FDG PET/CT in the management of squamous cell carcinoma of the head and neck and thyroid carcinoma Journal of Nuclear Medicine 2007 48 1, supplement 58S 67S
25. Schder H., Yeung H. W., Positron emission imaging of head and neck cancer, including thyroid carcinoma Seminars in Nuclear Medicine 2004 34 3 180 197
26. Nemzek W. R., Hecht S., Gandour-Edwards R., Donald P., McKennan K., Perineural spread of head and neck tumors: how accurate is MR imaging? American Journal of Neuroradiology 1998 19 4 701 706
27. Myers L. L., Wax M. K., Nabi H., Simpson G. T., Lamonica D., Positron emission tomography in the evaluation of the N0 neck Laryngoscope 1998 108 2 232 236
28. Nahmias C., Carlson E. R., Duncan L. D., Positron emission tomography/computerized tomography (PET/CT) scanning for preoperative staging of patients with oral/head and neck cancer Journal of Oral and Maxillofacial Surgery 2007 65 12 2524 2535
29. Schoder H., Carlson D. L., Kraus D. H., 18F-FDG PET/CT for detecting nodal metastases in patients with oral cancer staged N0 by clinical examination and CT/MRI Journal of Nuclear Medicine 2006 47 5 755 762
30. Schroeder U., Dietlein M., Wittekindt C., Is there a need for positron emission tomography imaging to stage the N0 neck in T1-T2 squamous cell carcinoma of the oral cavity or oropharynx? Annals of Otology, Rhinology, and Laryngology 2008 117 11 854 863
31. Kovacs A. F., Dobert N., Gaa J., Menzel C., Bitter K., Positron emission tomography in combination with sentinel node biopsy reduces the rate of elective neck dissections in the treatment of oral and oropharyngeal cancer Journal of Clinical Oncology 2004 22 19 3973 3980
32. Rahima B., Shingaki S., Nagata M., Saito C., Prognostic significance of perineural invasion in oral and oropharyngeal carcinoma Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 2004 97 4 423 431
33. Wenzel S., Sagowski C., Kehrl W., Metternich F. U., The prognostic impact of metastatic pattern of lymph nodes in patients with oral and oropharyngeal squamous cell carcinomas European Archives of Oto-Rhino-Laryngology 2004 261 5 270 275
34. Ng S.-H., Chan S.-C., Yen T.-C., Staging of untreated nasopharyngeal carcinoma with PET/CT: comparison with conventional imaging work-up European Journal of Nuclear Medicine and Molecular Imaging 2009 36 1 12 22
35. Chua M. L., Ong S. C., Wee J. T., Comparison of 4 modalities for distant metastasis staging in endemic nasopharyngeal carcinoma Head and Neck 2009 31 3 346 354
36. Liu F.-Y., Lin C.-Y., Chang J. T., 18F-FDG PET can replace conventional work-up in primary M staging of nonkeratinizing nasopharyngeal carcinoma Journal of Nuclear Medicine 2007 48 10 1614 1619
37. Yen T.-C., Chang J.T., Ng S.-H., The value of 18F-FDG PET in the detection of stage M0 carcinoma of the nasopharynx Journal of Nuclear Medicine 2005 46 3 405 410
38. Sigg M. B., Steinert H., Gratz K., Hugenin P., Stoeckli S., Eyrich G. K., Staging of head and neck tumors: [18F]fluorodeoxyglucose positron emission tomography compared ith physical examination and conventional imaging modalities Journal of Nuclear Medicine 2003 61 1022 1029
39. Schwartz D. L., Rajendran J., Yueh B., Staging of head and neck squamous cell cancer with extended-field FDG-PET Archives of Otolaryngology 2003 129 11 1173 1178
40. Grau C., Johansen L. V., Jakobsen J., Geertsen P., Andersen E., Jensen B. B., Cervical lymph node metastases from unknown primary tumours: results from a national survey by the Danish Society for Head and Neck Oncology Radiotherapy and Oncology 2000 55 2 121 129
41. Beld D., Jereczek-Fossa B. A., DOnofrio A., Role of radiotherapy in the treatment of cervical lymph node metastases from an unknown primary site: retrospective analysis of 113 patients International Journal of Radiation Oncology Biology Physics 2007 69 4 1051 1058
42. Zimmer L., Branstetter B., Nayak J., Johnson J. T., Current use of 18F-fluorodeoxyglucose positron emission tomography and combined positron emission tomography and computed tomography in squamous cell carcinoma of the head and neck Laryngoscope 2005 115 11 2029 2034
43. Mendenhall W. M., Mancuso A. A., Amdur R. J., Stringer S. P., Villaret D. B., Cassisi N. J., Squamous cell carcinoma metastatic to the neck from an unknown head and neck primary site American Journal of Otolaryngology 2001 22 4 261 267
44. Schmalbach C., Miller F., Occult primary head and neck carcinoma Current Oncology Reports 2007 9 2 139 146
45. Rusthoven K. E., Koshy M., Paulino A. C., The role of fluorodeoxyglucose positron emission tomography in cervical lymph node metastases from an unknown primary tumor Cancer 2004 101 11 2641 2649
46. Padovani D., Aimoni C., Zucchetta P., Paluzzi A., Pastore A., 18-FDG PET in the diagnosis of laterocervical metastases from occult carcinoma European Archives of Oto-Rhino-Laryngology 2009 266 2 267 271
47. Silva P., Hulse P., Sykes A. J., Should FDG-PET scanning be routinely used for patients with an unknown head and neck squamous primary? Journal of Laryngology and Otology 2007 121 2 149 153
48. Fakhry N., Jacob T., Paris J., Contribution of 18-F-FDG PET for detection of head and neck carcinomas with an unknown primary tumor Ann Otolaryngol Chir Cervicofac 2006 123 1 17 25
49. Wong W. L., Saunders M., The impact of FDG PET on the management of occult primary head and neck tumours Clinical Oncology 2003 15 8 461 466
50. Fogarty G. B., Peters L. J., Stewart J., Scott C., Rischin D., Hicks R. J., The usefulness of fluorine 18-labelled deoxyglucose positron emission tomography in the investigation of patients with cervical lymphadenopathy from an unknown primary tumor Head and Neck 2003 25 2 138 145
51. Johansen J., Eigtved A., Buchwald C., Theilgaard S. A., Hansen H. S., Implication of 18F-fluoro-2-deoxy-D-glucose positron emission tomography on management of carcinoma of unknown primary in the head and neck: a Danish cohort study Laryngoscope 2002 112 11 2009 2014
52. Kresnik E., Mikosch P., Gallowitsch H. J., Evaluation of head and neck cancer with 18F-FDG pet: a comparison with conventional methods European Journal of Nuclear Medicine 2001 28 7 816 821
53. Jungehulsing M., Scheidhauer K., Damm M., 2[F]-fluoro-2-deoxy-D-glucose positron emission tomography is a sensitive tool for the detection of occult primary cancer (carcinoma of unknown primary syndrome) with head and neck lymph node manifestation Otolaryngology 2000 123 3 294 301
54. Johansen J., Buus S., Loft A., Prospective study of 18FDG-PET in the detection and management of patients with lymph node metastases to the neck from an unknown primary tumor: results from the Dahanca-13 study Head and Neck 2008 30 4 471 478
55. Roh J.-L., Kim J. S., Lee J. H., Utility of combined 18F- fluorodeoxyglucose-positron emission tomography and computed tomography in patients with cervical metastases from unknown primary tumors Oral Oncology 2009 45 3 218 224
56. Adelstein D. J., Li Y., Adams G. L., An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer Journal of Clinical Oncology 2003 21 1 92 98
57. Martin R. C., Fulham M., Shannon K. F., Accuracy of positron emission tomography in the evaluation of patients treated with chemoradiotherapy for mucosal head and neck cancer Head and Neck 2009 31 2 244 250
58. Velazquez R. A., McGuff H. S., Sycamore D., Miller F. R., The role of computed tomographic scans in the management of the n-positive neck in head and neck squamous cell carcinoma after chemoradiotherapy Archives of Otolaryngology 2004 130 1 74 77
59. Bronstein A. D., Nyberg D. A., Schwartz A. N., Shuman W. P., Griffin B. R., Soft-tissue changes after head and neck radiation: CT findings American Journal of Neuroradiology 1989 10 1 171 175
60. Terhaard C. H., Bongers V., van Rijk P. P., Hordijk G.-J., F-18-fluoro-deoxy-glucose positron-emission tomography scanning in detection of local recurrence after radiotherapy for laryngeal/pharyngeal cancer Head and Neck 2001 23 11 933 941
61. Greven K. M., Williams D. W. III, McGuirt W. F. Sr., Serial positron emission tomography scans following radiation therapy of patients with head and neck cancer Head and Neck 2001 23 11 942 946
62. Greven K. M., Williams D. W., Keyes J. W. Jr., Positron emission tomography of patients with head and neck carcinoma before and after high dose irradiation Cancer 1994 74 4 1355 1359
63. Gordin A., Golz A., Keidar Z., Daitzchman M., Bar-Shalom R., Israel O., The role of FDG-PET/CT imaging in head and neck malignant conditions: impact on diagnostic accuracy and patient care Otolaryngology 2007 137 1 130 137
64. Conessa C., Herv S., Foehrenbach H., Poncet J.-L., FDG-PET scan in local follow-up of irradiated head and neck squamous cell carcinomas Annals of Otology, Rhinology, and Laryngology 2004 113 8 628 635
65. Kitagawa Y., Nishizawa S., Sano K., Prospective comparison of F 18 -FDG PET with conventional imaging modalities (MRI, CT, and G 67 a scintigraphy) in assessment of combined intraarterial chemotherapy and radiotherapy for head and neck carcinoma Journal of Nuclear Medicine 2003 44 2 198 206
66. Yao M., Smith R. B., Graham M. M., The role of FDG PET in management of neck metastasis from head-and-neck cancer after definitive radiation treatment International Journal of Radiation Oncology Biology Physics 2005 63 4 991 999
67. Stokkel M., Terhaard C., Mertens I, Hordijk I.-J., van Rijk P. P., Fluorine-18-FDG detection of laryngeal cancer postradiotherapy using dual-head coincidence imaging Journal of Nuclear Medicine 1998 39 8 1385 1387
68. Kim S. Y., Lee S.-W., Nam S. W., The feasibility of 18F-FDG PET scans 1 month after completing radiotherapy of squamous cell carcinoma of the head and neck Journal of Nuclear Medicine 2007 48 3 373 378
69. Delbeke D., Martin W. H., Positron emission tomography imaging in oncology Radiologic Clinics of North America 2001 39 5 883 917
70. Kostakoglu L., Goldsmith S. J., PET in the assessment of therapy response in patients with carcinoma of the head and neck and of the esophagus Journal of Nuclear Medicine 2004 45 1 56 68
71. Rogers J. W., Greven K. M., McGuirt W. F., Can post-rt neck dissection be omitted for patients with head-and-neck cancer who have a negative pet scan after definitive radiation therapy? International Journal of Radiation Oncology Biology Physics 2004 58 3 694 697
72. Ong S. C., Schder H., Lee N. Y., Clinical utility of 18F-FDG PET/CT in assessing the neck after concurrent chemoradiotherapy for locoregional advanced head and neck cancer Journal of Nuclear Medicine 2008 49 4 532 540
73. Yao M., Smith R. B., Hoffman H. T., Clinical significance of postradiotherapy [18F]-fluorodeoxyglucose positron emission tomography imaging in management of head-and-neck cancer-a long-term outcome report International Journal of Radiation Oncology Biology Physics 2009 74 1 9 14
74. Tan A., Adelstein D., Rybicki L., Ability of positron emission tomography to detect residual neck node disease in patients with head and neck squamous cell carcinoma after definitive chemoradiotherapy Archives of Otolaryngology 2007 133 5 435 440
75. Klabbers B. M., Lammertsma A. A., Slotman B. J., The value of positron emission tomography for monitoring response to radiotherapy in head and neck cancer Molecular Imaging and Biology 2003 5 4 257 270
76. Ryan W. R., Fee W. E. Jr., Le Q.-T., Pinto H. A., Positron-emission tomography for surveillance of head and neck cancer Laryngoscope 2005 115 4 645 650
77. Abgral R., Querellou S., Potard G., Does F 18 -FDG PET/CT improve the detection of posttreatment recurrence of head and neck squamous cell carcinoma in patients negative for disease on clinical follow-up? Journal of Nuclear Medicine 2009 50 1 24 29
78. Wang Y.-F., Liu R.-S., Chu P.-Y., Positron emission tomography in surveillance of head and neck squamous cell carcinoma after definitive chemoradiotherapy Head and Neck 2009 31 4 442 451
79. Cermik T. F., Mavi A., Acikgoz G., Houseni M., Dadparvar S., Alavi A., FDG PET in detecting primary and recurrent malignant salivary gland tumors Clinical Nuclear Medicine 2007 32 4 286 291
80. lvarez Prez R. M., Borrego Dorado I., Ruiz Franco-Baux J.V., Vzquez Albertino R. J., Evaluation of efficacy and clinical impact of positron emission tomography with 18F fluoro-deoxyglucose in patients with suspicion of recurrent head and neck cancer or distant metastases Revista Espanola de Medicina Nuclear 2007 26 1 30 39
81. Salaun P. Y., Abgral R., Querellou S., Does 18fluoro-fluorodeoxyglucose positron emission tomography improve recurrence detection in patients treated for head and neck squamous cell carcinoma with negative clinical follow-up? Head and Neck 2007 29 12 1115 1120
82. Goerres G. W., Schmid D. T., Bandhauer F., Positron emission tomography in the early follow-up of advanced head and neck cancer Archives of Otolaryngology 2004 130 1 105 109
83. Kubota K., Yokoyama J., Yamaguchi K., FDG-PET delayed imaging for the detection of head and neck cancer recurrence after radio-chemotherapy: comparison with MRI/CT European Journal of Nuclear Medicine and Molecular Imaging 2004 31 4 590 595
84. Wong R. J., Current status of FDG-PET for head and neck cancer Journal of Surgical Oncology 2008 97 8 649 652
85. Soto D. E., Kessler M. L., Piert M., Eisbruch A., Correlation between pretreatment FDG-PET biological target volume and anatomical location of failure after radiation therapy for head and neck cancers Radiotherapy and Oncology 2008 89 1 13 18
86. Rothschild S., Studer G., Seifert B., PET/CT staging followed by intensity-modulated radiotherapy (IMRT) improves treatment outcome of locally advanced pharyngeal carcinoma: a matched-pair comparison Radiation Oncology 2007 2 1
87. Wang D., Schultz C. J., Jursinic P. A., Initial experience of FDG-PET/CT guided IMRT of head-and-neck carcinoma International Journal of Radiation Oncology Biology Physics 2006 65 1 143 151
88. Breen S. L., Publicover J., De Silva S., Intraobserver and interobserver variability in GTV delineation on FDG-PET-CT images of head and neck cancers International Journal of Radiation Oncology Biology Physics 2007 68 3 763 770
89. El-Bassiouni M., Ciernik I. F., Davis J. B., [18FDG] PET-CT-based intensity-modulated radiotherapy treatment planning of head and neck cancer International Journal of Radiation Oncology Biology Physics 2007 69 1 286 293
90. Koshy M., Paulino A. C., Howell R., Schuster D., Halkar R., Davis L. W., F-18 FDG PET-CT fusion in radiotherapy treatment planning for head and neck cancer Head and Neck 2005 27 6 494 502
91. Heron D. E., Andrade R. S., Flickinger J., Hybrid PET-CT simulation for radiation treatment planning in head-and-neck cancers: a brief technical report International Journal of Radiation Oncology Biology Physics 2004 60 5 1419 1424
92. Ciernik I. F., Dizendorf E., Baumert B. G., Radiation treatment planning with an integrated positron emission and computer tomography (PET/CT): a feasibility study International Journal of Radiation Oncology Biology Physics 2003 57 3 853 863
93. Nishioka T., Shiga T., Shirato H., Image fusion between 18FDG-PET and MRI/CT for radiotherapy planning of oropharyngeal and nasopharyngeal carcinomas International Journal of Radiation Oncology Biology Physics 2002 53 4 1051 1057
94. Ahn P. H., Garg M. K., Positron emission tomography/computed tomography for target delineation in head and neck cancers Seminars in Nuclear Medicine 2008 38 2 141 148
95. Paulino A. C., Johnstone P. A., 18F-FDG PET in radiotherapy treatment planning: Pandoras box? International Journal of Radiation Oncology Biology Physics 2004 59 2 4 5
96. Berson A. M., Stein N. F., Riegel A. C., Variability of gross tumor volume delineation in head-and-neck cancer using PET/CT fusion, part II: the impact of a contouring protocol Medical Dosimetry 2009 34 1 30 35
97. Geets X., Lee J. A., Bol A., Lonneux M., Grgoire V., A gradient-based method for segmenting FDG-PET images: methodology and validation European Journal of Nuclear Medicine and Molecular Imaging 2007 34 9 1427 1438
98. Nordsmark M., Bentzen S. M., Rudat V., Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy: an international multicenter study Radiotherapy and Oncology 2005 77 1 18 24
99. Krause B. J., Beck R., Souvatzoglou M., Piert M., PET and PET/CT studies of tumor tissue oxygenation Quarterly Journal of Nuclear Medicine and Molecular Imaging 2006 50 1 28 43
100. Dunst J., Stadler P., Becker A., Tumor volume and tumor hypoxia in head and neck cancers: the amount of the hypoxic volume is important Strahlentherapie und Onkologie 2003 179 8 521 526
101. Lee S. T., Scott A. M., Hypoxia positron emission tomography imaging with 18F-fluoromisonidazole Seminars in Nuclear Medicine 2007 37 6 451 461
102. Komar G., Seppnen M., Eskola O., 18F-EF5: a new PET tracer for imaging hypoxia in head and neck cancer Journal of Nuclear Medicine 2008 49 12 1944 1951
103. Chao K. S., Bosch W. R., Mutic S., A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy International Journal of Radiation Oncology Biology Physics 2001 49 4 1171 1182
104. Souvatzoglou M., Grosu A. L., Rper B., Tumour hypoxia imaging with [18F]FAZA PET in head and neck cancer patients: a pilot study European Journal of Nuclear Medicine and Molecular Imaging 2007 34 10 1566 1575
105. Balogova S., Pri S., Kerrou K., Prospective comparison of FDG and FET PET/CT in patients with head and neck squamous cell carcinoma Molecular Imaging and Biology 2008 10 6 364 373
106. Pauleit D., Zimmermann A., Stoffels G., 18F-FET PET compared with18F-FDG PET and CT in patients with head and neck cancer Journal of Nuclear Medicine 2006 47 2 256 261
107. de Langen A. J., Klabbers B., Lubberink M., Reproducibility of quantitative 18F- 3 ′ -deoxy- 3 ′-fluorothymidine measurements using positron emission tomography European Journal of Nuclear Medicine and Molecular Imaging 2009 36 3 389 395
108. Beer A. J., Grosu A.-L., Carlsen J., [18F]Galacto-RGD positron emission tomography for imaging of v 3 expression on the neovasculature in patients with squamous cell carcinoma of the head and neck Clinical Cancer Research 2007 13 22 6610 6616