Synthesis of tipranavir analogues as non-peptidic HIV protease inhibitors

Letters in Organic Chemistry

Volumn 6, Issue 2, 2009, Pages 130-133

  Ding, Yili ^a   Vara Prasad, Chamakura V N S ^a   Smith, Kenneth L ^a   Chang, Eugene ^a   Hong, Jian ^a,b   Yao, Nanhua ^a  

^a Valeant Pharmaceuticals International   (United States)

^b RIGEL PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 69249182652     PISSN: 15701786     EISSN: None     Source Type: Journal    
DOI: 10.2174/157017809787582807     Document Type: Article

References (10)

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8. 4Cl solution. After work up and purification of the crude product, the desired compound 2 was obtained as a white solid in 45% yield.
9. -.
10. Tipranavir was used as the standard compound for the HIV protease inhibitory activity assay (1 nM Ki).