Prognostic factors of radiotherapy in patients with node-positive thoracic esophageal squamous cell carcinoma after radical surgery

Diseases of the Esophagus

Volumn 22, Issue 6, 2009, Pages 490-495

  Lu, Jin Cheng ^a   Tao, Hua ^a   Chen, Zhen Zhang ^a   Qian, Pu Dong ^a  

^a JIANGSU CANCER HOSPITAL   (China)

Author keywords

Esophageal carcinoma; Postoperative radiotherapy; Prognostic factor; Radical surgery; Sequential chemoradiotherapy

Indexed keywords

CISPLATIN; FLUOROURACIL;

ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER INVASION; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; DISEASE FREE SURVIVAL; ELECTRON THERAPY; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; ESOPHAGUS RESECTION; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; METASTASIS POTENTIAL; OUTCOME ASSESSMENT; PERICARDIAL EFFUSION; PLEURA EFFUSION; PRIORITY JOURNAL; PROGNOSIS; RADIATION DOSE FRACTIONATION; THORACOTOMY;

ADULT; AGED; CARCINOMA, SQUAMOUS CELL; CHEMOTHERAPY, ADJUVANT; DISEASE-FREE SURVIVAL; ESOPHAGEAL NEOPLASMS; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RADIOTHERAPY, ADJUVANT; RETROSPECTIVE STUDIES;

EID: 69249146195     PISSN: 11208694     EISSN: 14422050     Source Type: Journal    
DOI: 10.1111/j.1442-2050.2008.00936.x     Document Type: Article

References (23)

1. Mariette C, Piessen G, Triboulet J P. Therapeutic strategies in oesophageal carcinoma: Role of surgery and other modalities. Lancet Oncol 2007; 8: 545-53.
2. Liao Z X, Cox J D, Komaki R. Radiochemotherapy of esophageal cancer. J Thorac Oncol 2007; 2: 553-68.
3. Teniere P, Hay J M, Fingerhut A, Fagniez P L. Postoperative radiation therapy does not increase survival after curative resection for squamous cell carcinoma of the middle and lower esophagus as shown by a multicenter controlled trial. Surg Gynecol Obstet 1991; 173: 123-9.
4. Fok M, Sham J S, Choy D, Cheng S W, Wong J. Postoperative radiotherapy for carcinoma of the esophagus: A prospective, randomized controlled study. Surgery 1993; 113: 138-47.
5. Zieren H U, Muller J M, Jacobi C A, Pichlmaier H, Muller R P, Staar S. Adjuvant postoperative radiation therapy after curative resection of squamous cell carcinoma of the thoracic esophagus: A prospective randomized study. World J Surg 1995; 19: 444-9.
6. Xiao Z F, Yang Z Y, Liang J et al. Value of radiotherapy after radical surgery for esophageal carcinoma: A report of 495 patients. Ann Thorac Surg 2003; 75: 331-6.
7. Xiao Z F, Yang Z Y, Miao Y J et al. Influence of number of metastatic lymph nodes on survival of curative resected thoracic esophageal cancer patients and value of radiotherapy: Report of 549 cases. Int J Radiat Oncol Biol Phys 2005; 62: 82-90.
8. Lu J C, Qian P D, Zha W W, Zhang Y Q. The meta-analysis of randomized controlled trial of prophylactic radiotherapy for esophageal carcinoma after curative resection. Xunzheng Yixue 2005; 5: 166-71.
9. Lu J C, Tao H, Zhang Y Q, et al. Extent of prophylactic postoperative radiotherapy after radical surgery of the thoracic esophageal squamous cell carcinoma. Dis Esophagus 2008; 21: 502-7.
10. Malthaner R A, Wong R K, Rumble R B, Zuraw L. Members of gastrointestinal cancer disease site group of cancer care Ontario's program in evidence-based care. Neoadjuvant or adjuvant therapy for respectable esophageal cancer: A systemic review and meta-analysis. BMC Med 2004; 2: 35.
11. Izbicki J R, Hosch S B, Pichlmeier U et al. Prognostic value of immunohistochemically identifiable tumor cells in lymph nodes of patients with completely resected esophageal cancer. N Engl J Med 1997; 337: 1188-94.
12. Hosch S B, Stoecklein N H, Pichlmeier U et al. Esophageal cancer: The mode of lymphatic tumor cell spread and its prognostic significance. J Clin Oncol 2001; 19: 1970-5.
13. Yamamoto M, Yamashita T, Matsubara T et al. Reevaluation of postoperative radiotherapy for thoracic esophageal carcinoma. Int J Radiat Oncol Biol Phys 1997; 37: 75-8.
14. Ando N, Iizuka T, Ide H et al. Surgery plus chemotherapy compared with surgery alone for localized squamous cell carcinoma of the thoracic esophagus: A Japan Clinical Oncology Group Study-JCOG9204. J Clin Oncol 2003; 21: 4592-6.
15. Liu H C, Hung S K, Huang C J etal. Esophagectomy for locally advanced esophageal cancer followed by chemoradiotherapy and adjuvant chemotherapy. World J Gastroenterol 2005; 11: 5367-72.
16. Rice T W, Adelstein D J, Chidel M A et al. Benefit of postoperative adjuvant chemoradiotherapy in locoregionally advanced esophageal carcinoma. J Thorac Cardiovasc Surg 2003; 126: 1590-6.
17. Bedard E L, Inculet R I, Malthaner R A et al. The role of surgery and postoperative chemoradiation therapy in patients with lymph node positive esophageal carcinoma. Cancer 2001; 91: 2423-30.
18. Wang Y X, Zhu S C, Li R et al. Clinical analysis of prophylactic postoperative radiotherapy or sequence radiotherapy and chemotherapy in esophageal carcinoma. Zhongliu Fangzhi Yanjiu 2005; 32: 171-4.
19. Mariette C, Piessen G, Briez N, Triboulet J P. The number of metastatic lymph nodes and the ratio between metastatic and examined lymph nodes are independent prognostic factors in esophageal cancer regardless of neoadjuvant chemoradiation or lymphadenectomy extent. Ann Surg 2008; 247: 365-71.
20. Roder J D, Busch R, Stein H J et al. Ratio of invaded to removed lymph nodes as a predictor of survival in squamous cell carcinoma of the oesophagus. Br J Surg 1994; 81: 410-3.
21. Nigro J J, DeMeester S R, Hagen J A et al. Node status in transmural esophageal adenocarcinoma and outcome after en bloc esophagectomy. J Thorac Cardiovasc Surg 1999; 117: 960-8.
22. Hölscher A H, Bollschweiler E, Bumm R etal. Prognostic factors of resected adenocarcinoma of the esophagus. Surgery 1995; 118: 845-55.
23. Hulscher J B, van Sandick J W, deBoer A G etal. Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the esophagus. N Engl J Med 2002; 347: 1662-9.