Tetramerization and cooperativity in Plasmodium falciparum glutathione S-transferase are mediated by atypic loop 113-119

Journal of Biological Chemistry

Volumn 284, Issue 33, 2009, Pages 22133-22139

  Liebau, Eva ^a   Dawood, Kutayba F ^b   Fabrini, Raffaele ^b   Fischer Riepe, Lena ^a   Perbandt, Markus ^c,d   Stella, Lorenzo ^b   Pedersen, Jens Z ^b   Bocedi, Alessio ^e,f   Petrarca, Patrizia ^b   Federici, Giorgio ^g   Ricci, Giorgio ^b,h  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c UNIVERSITY OF LÜBECK   (Germany)

^d DESY   (Germany)

^e ROMA TRE UNIVERSITY   (Italy)

^f DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g Bambin Gesù Pediatric Cardiology Hospital   (Italy)

^h NONE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL DRUG; COOPERATIVE MECHANISMS; COOPERATIVE PHENOMENON; COOPERATIVITY; ENZYME INACTIVATION; FLUORESCENCE ANISOTROPY; GLUTATHIONE-S-TRANSFERASE; GLUTATHIONES; NATIVE ENZYMES; PARASITE-; PLASMODIUM FALCIPARUM; POINT MUTATIONS; PROTEIN SEGMENTS; REDOX STATUS; SITE DIRECTED MUTAGENESIS; STEADY-STATE KINETICS; STRUCTURAL DIFFERENCES; TETRAMERIZATION; TETRAMERS;

CELL MEMBRANES; ENZYME ACTIVITY;

ENZYMES;

GLUTATHIONE DISULFIDE; GLUTATHIONE TRANSFERASE; HEMIN; ISOENZYME; TETRAMER;

ANISOTROPY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; FLUORESCENCE ANALYSIS; GEL PERMEATION CHROMATOGRAPHY; NONHUMAN; OXIDATION REDUCTION STATE; PLASMODIUM FALCIPARUM; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; SITE DIRECTED MUTAGENESIS; STEADY STATE;

ANIMALS; BINDING SITES; DIMERIZATION; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HEMIN; KINETICS; MODELS, BIOLOGICAL; MOLECULAR CONFORMATION; MUTAGENESIS, SITE-DIRECTED; MUTATION; OXIDATION-REDUCTION; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

PLASMODIUM FALCIPARUM;

EID: 69249146108     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.015198     Document Type: Article

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