Anticonvulsant Met-enkephalin analogues containing backbone spacers reveal alternative non-opioid signaling in the brain

ACS Chemical Biology

Volumn 4, Issue 8, 2009, Pages 659-671

  Lee, Hee Kyoung ^a   Smith, Misty D ^a   Smith, Brian J ^b   Grussendorf, Joel ^a   Xu, Liping ^c   Gillies, Robert J ^c   White, H Steve ^a   Bulaj, Grzegorz ^a  

^a UNIVERSITY OF UTAH   (United States)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALIN 4 AMINOBUTYRIC ACID; ENKEPHALIN 5 AMINO 3 OXAPENTANOIC ACID; ENKEPHALIN 5 AMINOPENTANOIC ACID; ENKEPHALIN 6 AMINOHEXANOIC ACID; ENKEPHALIN 7 AMINOHEPTANOIC ACID; GLYCINE; KETOMETHYLENE LEUCINE ENKEPHALIN; LEUCINE ENKEPHALIN; METENKEPHALIN; METENKEPHALIN DERIVATIVE; MU OPIATE RECEPTOR; NALOXONAZINE; NALOXONE; SIGMA OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; CALCIUM MOBILIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG DOSE INCREASE; DRUG HALF LIFE; DRUG STRUCTURE; FOCAL EPILEPSY; HUMAN; HUMAN CELL; HYDROGEN BOND; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; ANTICONVULSANTS; BRAIN; CALCIUM; CELL LINE; CRICETINAE; CRICETULUS; ENKEPHALIN, METHIONINE; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BINDING; RECEPTORS, OPIOID, DELTA;

EID: 69249136291     PISSN: 15548929     EISSN: None     Source Type: Journal    
DOI: 10.1021/cb900045c     Document Type: Article

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