Assessment of the extracts of Centaurea tchihatcheffii fischer for anti-inflammatory and analgesic activities in animal models

Tropical Journal of Pharmaceutical Research

Volumn 8, Issue 3, 2009, Pages 193-200

  Koca, Ufuk ^a   Toker, Gülnur ^a   Akkol, Esra Küpeli ^a  

^a GAZI UNIVERSITY   (Turkey)

Author keywords

Analgesic; Anti inflammatory; Centaurea tchihatcheffii; Flowers; Leaves; Stems

Indexed keywords

1,4 BENZOQUINONE; ACETYLSALICYLIC ACID; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; CARRAGEENAN; CENTAUREA TCHIHATCHEFFII EXTRACT; INDOMETACIN; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BODY WEIGHT; CENTAUREA; CENTAUREA TCHIHATCHEFFII; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVITY; FLOWER; MALE; MOUSE; NONHUMAN; PAW EDEMA; PHYTOCHEMISTRY; PLANT LEAF; THIN LAYER CHROMATOGRAPHY;

EID: 69249111336     PISSN: 15965996     EISSN: 15969827     Source Type: Journal    
DOI: 10.4314/tjpr.v8i3.44532     Document Type: Article

References (23)

1. Seçmen Ö, Gemici Y, Görk G, Bekat L, Leblebici E. Systematics of Seed Plants. Bornova, İzmir, Turkey, Aegean University Press, 1995, pp 301-396, (In Turkish).
2. Wagenitz G. Centaurea L. In: Flora of Turkey and The East Aegean Islands, Ed. Davis, P.H V, Edinburgh, Edinburgh University Press, 1975, pp 465-586.
3. nd Edition, Istanbul, Nobel Tip Basimevi, 1999, pp.316.
4. Erol MK, Tuzlaci, E. Plants used in folk medicine in the region of Eǧirdir (Isparta) "XI.th Meeting on plant drug active constituents' Ed. Coşkun, M, Ankara University Pharmacy Faculty No:75, Ankara, Ankara Universitesi Basimevi, 1997, pp. 466-475.
5. Chucla MT, Lamela M, Gato A, Cadavid I. Centaurea corcubionensis: A study of its hypoglycemic activity in rats. Planta Med, 1988; 107-109. (Pubitemid 18102721)
6. Talhouk RS, El-Jouni W, Baalbaki R, Gali-Muhtasib H, Kogan J, Talhouk AN. Anti-inflammatory bioactivities in water extract of Centaurea ainetensis. J Med Plants Res, 2008; 2:24-33.
7. Orallo F, Lamela M, Camina M, Uriatre E, Calleja M. Preliminary study of the potential vasodilator effects on rat aorta of centaurein and centaureidin, two flavonoids from Centaurea corcubionensis. Planta Med, 1998; 64:116-119. (Pubitemid 28153268)
8. Barrero AF, Herrador MM, Arteaga P, Cabrera E, Rodriguez-Garcia I, Garcia-Moreno M, Gravalos DG. Cytotoxic activity of flavonoids from Carthamus arborescens, Ononis natrix ssp. ramosissima and Centaurea malacitana. Fitoterapia, 1997; 68:281-283.
9. Gürkan E, Sarioǧlu I, Oksüz S. Cytotoxicity assay of some plants from Asteraceae. Fitoterapia, 1998; 69:81-82.
10. Wei HX, Gao WY, Tian YK, Guan YK, Huang MH, Cheng DL. New eudesmane sesquiterpene and thiophene derivatives from the roots of Rhaponticum uniflorum. Pharmazie, 1997; 52:245-247.
11. Yeşilada E., Küpeli E. Berberis crategina DC. Root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats. J Ethnopharmacol, 2002; 79: 237-248.
12. Kasahara Y, Hikino H, Tsurufiji S, Watanabe M, Ohuchi K. Antiinflammatory actions of ephedrines in acute inflammations. Planta Med, 1985; 51:325-331. (Pubitemid 15014330)
13. De Young LM, Kheifets JB, Ballaron SJ, Young JM. Edema and cell infiltration in the phorbol ester treated mouse ear are temporally separate and can be differently modulated by pharmacologic agents. Agents and Action, 1989; 26:335-341.
14. Okun R, Liddon SC, Lasagnal L. The effect of aggregation, electric shock and adrenergic bloking drugs on inhibition of the "writhing syndrome". J Pharmacol Exp Ther, 1963; 139:107-109.
15. Szolcsanyi J, Helyes Z, Oroszi G, Nemeth J, Pinter E. Release of somatostatin and its role in the mediation of the anti-inflammatory effect induced by antidromic stimulation of sensory fibres of rat sciatic nerve. Br J Pharmacol, 1998; 123:936-942 (Pubitemid 28085395)
16. Gamache DA, Povlishock JT, Ellis EF. Carrageenan induced brain inflammation, characterization of the model. J Neurosurg, 1986; 65:679-685.
17. Garcia-Pastor P, Randazzo A., Gomez-Paloma L, Alcaraz MJ, Paya M. Effects of petrosaspongiolide M, a novel phospholipase A2 inhibitor, on acute and chronic inflammation. J Pharmacol Exp Ther, 1999; 289:166-172. (Pubitemid 29156025)
18. Negrete R, Backhouse N, Cajigal I, Delporte C, Cassels BK, Breitmaier E, Eckhardt G. Two new antiinflamatory elemanolides from Centaurea chilensis. J Ethnopharmacol, 1993; 40:149-153. (Pubitemid 24012054)
19. Kulkarni SK, Mehta AK, Kunchandy J. Anti-inflammatory actions of clonidine, guanfacine and B-HT 920 against various inflammagen-induced acute paw oedema in rats. Arch Int Pharmacodyn Ther, 1986; 279:324-334. (Pubitemid 16124979)
20. Nishizuka Y. The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature, 1988; 334:661-665.
21. Negrete R, Backhouse N, Avendano S, San Martin A. Dehydrocostus lactone and 8β-hydroxydehydrocostus lactone in Centaurea chilensis Hook and Arn. Planta Med, 1984; 18:226-232. (Pubitemid 15147793)
22. Garbacki N, Gloaguen V, Damas J, Bodart P, Tits M, Angenot L. Anti-inflamatory and immunological effects of Centaurea cyanus flower-heads. J Ethnopharmacol, 1999; 68:235-241. (Pubitemid 29502480)
23. Karamenderes C, Konyalioglu S, Khan S, Khan I. Total phenolic contents, free radical scavenging activities and inhibitory effects on the activation of NF-kappa B of eight Centaurea L. species. Phytother Res, 2007; 21:488-491. (Pubitemid 46715094)