Uric acid: More to learn, more experiments to do

American Journal of Hypertension

Volumn 22, Issue 9, 2009, Pages 952-953

  Johnson, Richard J ^a,b   Rivard, Chris ^a   Nakagawa, Takahiko ^a,b   Sautin, Yuri Y ^b   Sanchez Lozada, L Gabriela ^a,c  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; OXIDOREDUCTASE INHIBITOR; TEMPOL; UNCLASSIFIED DRUG; URATE OXIDASE; URATE OXIDASE INHIBITOR; URIC ACID;

ANTIHYPERTENSIVE ACTIVITY; ANTIOXIDANT ACTIVITY; ARTERY DILATATION; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR DISEASE; CAROTID ARTERY; CELL PROTECTION; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME INHIBITION; HUMAN; HYPERTENSION; HYPERURICEMIA; NONHUMAN; NOTE; PRIORITY JOURNAL;

ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HUMANS; HYPERURICEMIA; NITRIC OXIDE; URATE OXIDASE; URIC ACID;

EID: 69249108533     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1038/ajh.2009.117     Document Type: Note

References (7)

1. Feig DI, Kang DH, Johnson RJ. Uric acid and cardiovascular risk. N Engl J Med 2008; 359:1811-1821.
2. Long DA, Newaz MA, Prabhakar SS, Price KL, Truong LD, Feng L, Mu W, Oyekan AO, Johnson RJ. Loss of nitric oxide and endothelial-derived hyperpolarizing factor-mediated responses in aging. Kidney Int 2005; 68: 2154-2163.
3. Sánchez-Lozada LG, Soto V, Tapia E, Avila-Casado C, Sautin YY, Nakagawa T, Franco M, Rodríguez-Iturbe B, Johnson RJ. Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia. Am J Physiol Renal Physiol 2008; 295:F1134-F1141.
4. Sánchez-Lozada LG, Tapia E, López-Molina R, Nepomuceno T, Soto V, Avila-Casado C, Nakagawa T, Johnson RJ, Herrera-Acosta J, Franco M. Effects of acute and chronic L-arginine treatment in experimental hyperuricemia. Am J Physiol Renal Physiol 2007; 292:F1238-F1244.
5. Kurra V, Eräranta A, Jolma P, Vehmas TI, Riutta A, Moilanen E, Tahvanainen A, Kalliovalkama J, Niemelä O, Myllymäki J, Mustonen J, Pörsti I. Hyperuricemia, oxidative stress, and carotid artery tone in experimental renal insufficiency. Am J Hypertens 2009; 22:964-970.
6. Nakagawa T, Hu H, Zharikov S, Tuttle KR, Short RA, Glushakova O, Ouyang X, Feig DI, Block ER, Herrera-Acosta J, Patel JM, Johnson RJ. A causal role for uric acid in fructose-induced metabolic syndrome. Am J Physiol Renal Physiol 2006; 290:F625-F631.
7. Johnson RJ, Sautin YY, Oliver WJ, Roncal C, Mu W, Gabriela Sanchez-Lozada L, Rodriguez-Iturbe B, Nakagawa T, Benner SA. Lessons from comparative physiology: could uric acid represent a physiologic alarm signal gone awry in western society? J Comp Physiol B, Biochem Syst Environ Physiol 2009; 179:67-76.