A stability indicating HPLC method for the determination of meloxicam in bulk and commercial formulations

Tropical Journal of Pharmaceutical Research

Volumn 8, Issue 3, 2009, Pages 257-264

  Bandarkar, Farzana S ^a   Vavia, Pradeep R ^b  

^a KUWAIT UNIVERSITY   (Kuwait)

^b INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Bulk and commercial formulations; Meloxicam; Reverse phase stability indicating HPLC; Stress degradation

Indexed keywords

ACETIC ACID; ACETONITRILE; MELOXICAM; WATER;

ACCURACY; ARTICLE; CALIBRATION; DRUG DEGRADATION; DRUG FORMULATION; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION STUDY;

EID: 69249107341     PISSN: 15965996     EISSN: 15969827     Source Type: Journal    
DOI: 10.4314/tjpr.v8i3.44543     Document Type: Article

References (18)

1. Turck D, Roth W, Busch U. A Review of the Clinical Pharmacokinetics of Meloxicam. Brit J Rheumatol, 1996; 35: 13-19.
2. Kathleen P. Martindale - The Complete Drug Reference, Pharmaceutical Press, London, UK, ed 32, 1999, pp 52-55.
3. Noble S, Balfour JA. Meloxicam. Drugs, 1996; 51(3): 424-431.
4. Davies NM, Skjodt NM. Clinical Pharmacokinetics of Meloxicam. Clin Pharmacokinet, 1999; 36(2): 115-122.
5. Gates BJ, Nguyen TT, Setter SM, Davies NM. Meloxicam: a reappraisal of pharmacokinetics, efficacy, safety. Expert Opin Pharmacother, 2005; 6 (12): 2117-2140.
6. Hassan EM. Spectrophotometric and Fluorimetric Methods for the Determination of Meloxicam in Dosage Forms. J Pharm Biomed Anal, 2002; 27: 771-793.
7. You WW, Liu Y, Wang ZB. Determination of Meloxicam by Ultraviolet Spectrophotometry. Chinese J Anal Chem, 1999, 27(7): 841-853.
8. Nemutlu E, Kir S. Validated Determination of Meloxicam in Tablets by Using UV Spectrophotometry. Hacettepe University Journal of The Faculty of Pharmacy, 2004; 24 (1): 13-24.
9. Nemutlu E, Kir S. Method Development and Validation for the Analysis of Meloxicam in Tablets by CZE. J Pharm Biomed Anal, 2003; 31(2): 393-405.
10. Altiokka G, Atkosar Z, Tuncel M. Pulse Polarographic Determination of Meloxicam. Die Pharmazie, 2000; 56(2): 184-203.
11. Radi A, El-Ries MA, El-Anwar F, El-Sherif Z. Electrochemical Oxidation of Meloxicam and its Determination in Tablet Dosage Form. Anal Lett, 2001; 34(5): 739-746. (Pubitemid 32476766)
12. Beltagi AM, Ghoneim MM, Radi A. Electrochemical Reduction of Meloxicam at Mercury Electrode and its Determination in Tablets. J Pharm Biomed Anal, 2002; 27: 795-809. (Pubitemid 34117666)
13. Radi AE, Ghoneim M, Beltagi A, Cathodic Adsorptive Stripping Square-Wave Voltammetry of the Anti-Inflammatory Drug Meloxicam. Chem Pharm Bull, 2001; 49(10): 1257-1261.
14. Rao RN, Meena S, Rao AR. An Overview of the Recent Developments in Analytical Methodologies for Determination of COX-2 Inhibitors in Bulk Drugs, Pharmaceuticals and Biological Matrices. J Pharm Biomed Anal, 2005; 39(3): 349-367. (Pubitemid 41196038)
15. Vignaduzzo SE, Castellano PM, Kaufman TS. Method development and validation for the simultaneous determination of meloxicam and pridinol mesylate using RP-HPLC and its application in drug formulations. J Pharm Biomed Anal, 2008; 46(2):219-225
16. Zawilla NH, Abdul-Azim Mohammad M, El-Kousy NM, El-Moghazy Aly SM. Determination of Meloxicam in Bulk and Pharmaceutical Formulations. J Pharm Biomed Anal, 2003; 32(6): 1135-1142. (Pubitemid 36930099)
17. Dasandi B, Saroj SH, Bhat KM. LC Determination and Pharmacokinetics of Meloxicam. J Pharm Biomed Anal, 2002; 28: 999-1008.
18. International Conference on Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use: Harmonised Triplicate Guideline on Validation of Analytical Procedures: Methodology, Recommended for Adoption at Step 4 of the ICH Process on November 1996 by the ICH Steering Committee, IFPMA, Switzerland