Angioinhibitory action of NK4 involves impaired extracellular assembly of fibronectin mediated by Perlecan-NK4 association

Journal of Biological Chemistry

Volumn 284, Issue 33, 2009, Pages 22491-22499

  Sakai, Katsuya ^a   Nakamura, Takahiro ^b   Matsumoto, Kunio ^b   Nakamura, Toshikazu ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY PURIFICATION; ANGIOGENESIS INHIBITORS; BASEMENT MEMBRANE; BASIC FIBROBLAST GROWTH FACTOR; BIFUNCTIONAL; CELL SPREADING; DNA SYNTHESISS; EXTRACELLULAR ASSEMBLY; FOCAL ADHESION KINASE; HEPARAN SULFATES; HEPATOCYTE GROWTH FACTOR; HUMAN ENDOTHELIAL CELLS; INHIBITORY EFFECT; MULTI DOMAINS; OVER-EXPRESSION; PERLECAN; PROTEOGLYCANS; RAC ACTIVATION; SMALL INTERFERENCE RNA; TYROSINE PHOSPHORYLATION; VASCULAR ENDOTHELIAL GROWTH FACTOR;

AMINO ACIDS; BIOACTIVITY; BLOOD VESSEL PROSTHESES; CELL CULTURE; CELL MEMBRANES; DNA; FIBROBLASTS; GENES; NUCLEIC ACIDS; PEPTIDES; PHOSPHORYLATION; RNA; SELF ASSEMBLY;

ENDOTHELIAL CELLS;

BASIC FIBROBLAST GROWTH FACTOR; FIBRONECTIN; FOCAL ADHESION KINASE; PERLECAN; RAC PROTEIN; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; VASCULOTROPIN;

ANTIANGIOGENIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

COLLAGEN; ENDOTHELIUM, VASCULAR; EXTRACELLULAR MATRIX; FIBRONECTINS; GENE EXPRESSION REGULATION; HEPARAN SULFATE PROTEOGLYCANS; HEPATOCYTE GROWTH FACTOR; HUMANS; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; NEOVASCULARIZATION, PATHOLOGIC; PROTO-ONCOGENE PROTEINS C-MET; RNA, SMALL INTERFERING; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 69249088890     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.025148     Document Type: Article

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