Computerized tomography measurement of visceral adiposity predicts plasma adiponectin levels and metastatic disease in patients with clear cell renal cell carcinoma

Current Urology

Volumn 2, Issue 4, 2009, Pages 188-193

  Chatterjee, Suman ^a   Kleinman, Nir ^a,b   Gharajeh, Aash ^a   Kapoor, Anil ^a,b   Whelan, J P ^a   Yemen, Brian ^a   Pinthus, Jehonathan H ^a,b,c  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c JURAVINSKI CANCER CENTRE   (Canada)

Author keywords

Adiponectin; Obesity; Renal cell cancer; Visceral fat

Indexed keywords

ADIPONECTIN;

ADIPOCYTE; ADULT; ARTICLE; BLOOD LEVEL; BODY MASS; CANCER GRADING; CANCER RISK; CLEAR CELL CARCINOMA; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DIABETES MELLITUS; DIET RESTRICTION; FEMALE; HORMONE BLOOD LEVEL; HUMAN; INTRAABDOMINAL FAT; KIDNEY CARCINOMA; KIDNEY FUNCTION; LINEAR REGRESSION ANALYSIS; MALE; METASTASIS; MORBIDITY; OBESITY; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SPINE; SUBCUTANEOUS FAT; TUMOR VOLUME; UMBILICUS; VERTEBRA BODY;

EID: 69249086581     PISSN: 16617649     EISSN: 16617657     Source Type: Journal    
DOI: 10.1159/000209831     Document Type: Article

References (34)

1. Chow WH, Gridley G, Fraumeni JF Jr, Jarvholm B: Obesity, hypertension, and the risk of kidney cancer in men. N Eng J Med 2000;343:1305-1311.
2. Setiawan VW, Strain DO, Nomura AM, Kolonel LN, Henderson BE: Risk factors for renal cell cancer: the multiethnic cohort. Am J Epidemiol 2007;166:932-940.
3. Pinthus JH, Kleinmann N, Tisdale B, Chat-terjee S, Lu JP, Gillis A, Hamlet T, Singh G, Farrokhyar F, Kapoor A: Lower Plasma Adi-ponectin Levels Are Associated with Larger Tumor Size and Metastasis in Clear-Cell Car-cinoma of the Kidney. Eur Urol 2008;54:866 -873.
4. Horiguchi A, Ito K, Sumitomo M, Kimura F, Asano T, Hayakawa M: Decreased serum adiponectin levels in patients with metastatic renal cell carcinoma. Jpn J Clin Oncol 2008; 38:106-111.
5. Spyridopoulos TN, Petridou ET, Skalkidou A, Dessypris N, Chrousos GP, Mantzoros CS: Low adiponectin levels are associated with renal cell carcinoma: a case-control study. Int J Cancer 2007;120:1573-1578.
6. Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsub-ara K, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y: Paradoxical decrease of an adipose-specific protein, adiponectin, in obe-sity. Biochem Biophys Res Commun 1999; 257:79-83.
7. Bonora E, Micciolo R, Ghiatas AA, Lancast-er JL, Alyassin A, Muggeo M, DeFronzo RA: Is it possible to derive a reliable estimate of human visceral and subcutaneous abdominal adipose tissue from simple anthropometric measurements? Metabolism 1995;44:1617-1625.
8. Romero-Corral A, Montori VM, Somers VK, Korinek J, Thomas RJ, Allison TG, Mook-adam F, Lopez-Jimenez F: Association of bodyweight with total mortality and with car-diovascular events in coronary artery disease: a systematic review of cohort studies. Lancet 2006;368:666-678.
9. Fox CS, Massaro JM, Hoffmann U, Pou KM, Maurovich-Horvat P, Liu CY, Vasan RS, Murabito JM, Meigs JB, Cupples LA, D'Agostino RB Sr, O'Donnell CJ: Abdomi-nal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation 2007;116:39-48.
10. Wajchenberg BL, Giannella-Neto D, da Sil-va ME, Santos RF: Depot-specific hormonal characteristics of subcutaneous and visceral adipose tissue and their relation to the meta-bolic syndrome. Horm Metab Res 2002;34: 616-621.
11. Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K: Adiponectin and adipo-nectin receptors in insulin resistance, diabe-tes, and the metabolic syndrome. J Clin In-vest 2006;116:1784-1792.
12. Ryo M, Nakamura T, Kihara S, Kumada M, Shibazaki S, Takahashi M, Nagai M, Mat-suzawa Y, Funahashi T: Adiponectin as a biomarker of the metabolic syndrome. Circ J 2004;68:975-981.
13. Kwon K, Jung SH, Choi C, Park SH: Recip-rocal association between visceral obesity and adiponectin: in healthy premenopausal women. Int J Cardiol 2005;101:385-390.
14. Lilm AS, Pedersen SB, Richelsen B: Adipo-nectin: action, regulation and association to insulin sensitivity. Obes Rev 2005;6:13-21.
15. Iwashima Y, Horio T, Kumada M, Suzuki Y, Kihara S, Rakugi H, Kawano Y, Funahashi T, Ogihara T: Adiponectin and renal function, and implication as a risk of cardiovascular disease. Am J Cardiol 2006;98:1603-1608.
16. Sobin LH: Urologic tumors; in Sobin LH, Wittekind CH (eds): TNM classification of malignant tumours, ed 6. New York, Wiley-Liss, 2002, pp 179-206.
17. Kobayashi J, Tadokoro N, Watanabe M, Shi-nomiya M: A novel method of measuring in-tra-abdominal fat volume using helical com-puted tomography. Int J Obes Relat Metab Disord 2002;26:398-402.
18. Poirier P, Despres JP: Waist circumference, visceral obesity, and cardiovascular risk. J Cardiopulm Rehabil 2003;23:161-169.
19. Oh TH, Byeon JS, Myung SJ, Yang SK, Choi KS, Chung JW, Kim B, Lee D, Byun JH, Jang SJ, Kim JH: Visceral obesity as a risk factor for colorectal neoplasm. J Gastroen-terol Hepatol 2008;23:411-417.
20. Parker AS, Lohse CM, Cheville JC, Thiel DD, Leibovich BC, Blute ML: Greater body mass index is associated with better patho-logic features and improved outcome among patients treated surgically for clear cell renal cell carcinoma. Urology 2006;68:741-746.
21. Kamat AM, Shock RP, Naya Y, Rosser CJ, Slaton JW, Pisters LL: Prognostic value of body mass index in patients undergoing ne-phrectomy for localized renal tumors. Urol-ogy 2004;63:46-50.
22. Schips L, Lipsky K, Zigeuner R, Gidaro S, Salfellner M, Rehak P, Pummer K, Hubmer G: Does overweight impact on the prognosis of patients with renal cell carcinoma? A sin-gle center experience of 683 patients. J Surg Oncol 2004;88:57-61.
23. Rodriguez A, Catalan V, Gomez-Ambrosi J, Frahbeck G: Visceral and subcutaneous adi-posity: are both potential therapeutic targets for tackling the metabolic syndrome? Curr Pharm Des 2007;13:2169-2175.
24. Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, Nakayama O, Makishima M, Matsuda M, Shimomura I: Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest 2004;114:1752-1761.
25. Barb D, Pazaitou-Panayiotou K, Mantzoros CS: Adiponectin: a link between obesity and cancer. Expert Opin Investig Drugs 2006;15: 917-931.
26. Brakenhielm E, Veitonmaki N, Cao R, Ki-hara S, Matsuzawa Y, Zhivotovsky B, Fu-nahashi T, Cao Y: Adiponectin-induced an-tiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc Natl Acad Sci USA 2004;101:2476-2481.
27. Rini BI, Small EJ: Biology and clinical de-velopment of vascular endothelial growth factor-targeted therapy in renal cell carcino-ma. J Clin Oncol 2005;23:1028-1043.
28. Slaton JW, Inoue K, Perrotte P, El-Naggar AK, Swanson DA, Fidler IJ, Dinney CP: Ex-pression levels of genes that regulate metasta-sis and angiogenesis correlate with advanced pathological stage of renal cell carcinoma. Am J Pathol 2001;158:735-743.
29. Volpe A, Panzarella T, Rendon RA, Haider MA, Kondylis FI, Jewett MA: The natural history of incidentally detected small renal masses. Cancer 2004;100:738-745.
30. Cartier A, Lemieux I, Alméras N, Tremblay A, Bergeron J, Després JP: Visceral Obesity and Plasma Glucose-Insulin Homeostasis: Contributions of Interleukin-6 and tumor ne-crosis factor-alpha in men. J Clin Endocrinol Metab 2008;93:1931-1938.
31. Costes V, Liautard J, Picot MC, Robert M, Lequeux N, Brochier J, Baldet P, Rossi JF: Expression of the interleukin 6 receptor in primary renal cell carcinoma. J Clin Pathol 1997;50:835-840.
32. Horiguchi A, Sumitomo M, Asakuma J, Asano T, Zheng R, Nanus DM, Hayakawa M: Increased serum leptin levels and over expression of leptin receptors are associated with the invasion and progression of renal cell carcinoma. J Urol 2006;176:1631-1635.
33. Li L, Gao Y, Zhang LL, He DL: Concomitant activation of the JAK/STAT3 and ERK1/2 signaling is involved in leptin-mediated pro-liferation of renal cell carcinoma Caki-2 cells. Cancer Biol Ther 2008;7:1793-1798.
34. Kobayashi J, Sasaki T, Watanabe M: The relationship of abdominal fat mass assessed by helical or conventional computed tomog-raphy to serum leptin concentration. J Ath-eroscler Thromb 2004;11:173-179.