NO-NSAIDs: Gastric-sparing nitric oxide-releasable prodrugs of non-steroidal anti-inflammatory drugs

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 18, 2009, Pages 5297-5301

  Nemmani, Kumar V S ^a   Mali, Sunil V ^a   Borhade, Namdev ^a   Pathan, Asif R ^a   Karwa, Manoj ^a   Pamidiboina, Venu ^a   Senthilkumar, S P ^a   Gund, Machhindra ^a   Jain, Arun K ^a   Mangu, Naveen K ^a   Dubash, Nauzer P ^a   Desai, Dattatraya C ^a   Sharma, Somesh ^a   Satyam, Apparao ^a  

^a Piramal Enterprises Limited   (India)

Author keywords

Gastric sparing NSAIDs; Nitric oxide donors; NO Aspirin; NO Diclofenac; NO NSAIDs; Prodrugs of NSAIDs

Indexed keywords

ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID 3 (NITROXYMETHYL)PHENYL ESTER; DICLOFENAC; NAPROXCINOD; NITRIC OXIDE RELEASING ACETYLSALICYLIC ACID; NITRIC OXIDE RELEASING DICLOFENAC; NITRIC OXIDE RELEASING NONSTEROID ANTIINFLAMMATORY AGENT; NITROFENAC; NITRONAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PRODRUG; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISULFIDE BOND; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG SAFETY; DRUG SYNTHESIS; GASTROINTESTINAL SYMPTOM; HUMAN; NONHUMAN; RAT; STOMACH ACID SECRETION; STOMACH ULCER;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; DICLOFENAC; NITRIC OXIDE; PRODRUGS; RATS; STOMACH;

RATTUS;

EID: 69149090364     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.07.142     Document Type: Article

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