Monochloramine produces reactive oxygen species in liver by converting xanthine dehydrogenase into xanthine oxidase

Toxicology and Applied Pharmacology

Volumn 239, Issue 3, 2009, Pages 268-272

  Sakuma, Satoru ^a   Miyoshi, Emi ^a   Sadatoku, Namiko ^a   Fujita, Junko ^a   Negoro, Miki ^a   Arakawa, Yukio ^a   Fujimoto, Yohko ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Monochloramine; Oxidative injury; Reactive oxygen species; Xanthine dehydrogenase; Xanthine oxidase

Indexed keywords

ALLOPURINOL; CYSTEINE; DICHLORODIHYDROFLUORESCEIN DIACETATE; DITHIOTHREITOL; METHIONINE; MONOCHLORAMINE; REACTIVE OXYGEN METABOLITE; XANTHINE DEHYDROGENASE; XANTHINE OXIDASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME METABOLISM; FLUORESCENCE ANALYSIS; IN VITRO STUDY; LIVER CELL; LIVER PARENCHYMA; MALE; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALS; CELLS, CULTURED; CHLORAMINES; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATOCYTES; LIVER; MALE; RATS; REACTIVE OXYGEN SPECIES; XANTHINE DEHYDROGENASE; XANTHINE OXIDASE;

RATTUS;

EID: 69049115028     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.06.006     Document Type: Article

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