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Volumn 73, Issue 8, 2009, Pages 1523-1530

Effects of pitavastatin on fasting and postprandial endothelial function and blood rheology in patients with stable coronary artery disease

Author keywords

Angina pectoris; Endothelial function; Oxidative stress; Postprandial dyslipidemia; Rheology

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ACETYLSALICYLIC ACID; ADIPONECTIN; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CHOLESTEROL; GLYCERYL TRINITRATE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PITAVASTATIN; TICLOPIDINE; TRIACYLGLYCEROL;

EID: 69049107753     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-08-0917     Document Type: Article
Times cited : (32)

References (55)
  • 1
    • 38149027125 scopus 로고    scopus 로고
    • Dietary Strategies for improving post-prandial glucose, lipids, inflammation, and cardiovascular health
    • O'Keefe JH, Gheewala NM, O'Keefe JO. Dietary Strategies for improving post-prandial glucose, lipids, inflammation, and cardiovascular health. J Am Coll Cardiol 2008; 51: 249-255.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 249-255
    • O'Keefe, J.H.1    Gheewala, N.M.2    O'Keefe, J.O.3
  • 3
    • 34447511196 scopus 로고    scopus 로고
    • Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
    • DOI 10.1001/jama.298.3.299
    • Nordestgaard B, Benn M, Schnohr P, Tybjaerg-Hansen A. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 2007; 298: 299-308. (Pubitemid 47080484)
    • (2007) Journal of the American Medical Association , vol.298 , Issue.3 , pp. 299-308
    • Nordestgaard, B.G.1    Benn, M.2    Schnohr, P.3    Tybjaerg-Hansen, A.4
  • 4
    • 0033047374 scopus 로고    scopus 로고
    • Impaired glucose tolerance is a risk factor for cardiovascular disease, but not impaired fasting glucose: The Funagata Diabetes Study
    • DOI 10.2337/diacare.22.6.920
    • Tominaga M, Eguchi H, Manaka H, Igarashi K, Kato T, Sekikawa A. Impaired glucose tolerance is a risk factor for cardiovascular disease, but not impaired fasting glucose: The Funagata Diabetes Study. Diabetes Care 1999; 22: 920-924. (Pubitemid 29241045)
    • (1999) Diabetes Care , vol.22 , Issue.6 , pp. 920-924
    • Tominaga, M.1    Eguchi, H.2    Manaka, H.3    Igarashi, K.4    Kato, T.5    Sekikawa, A.6
  • 6
    • 34547957993 scopus 로고    scopus 로고
    • Postprandial Hyperglycemia/Hyperlipidemia (Postprandial Dysmetabolism) Is a Cardiovascular Risk Factor
    • DOI 10.1016/j.amjcard.2007.03.107, PII S000291490701096X
    • O'Keefe JH, Bell DS. The post-prandial hyperglycemia/hyperlipemia (postprandial dysmetabolism) is a cardiovascular risk factor. Am J Cardiol 2007; 100: 899-904. (Pubitemid 47268287)
    • (2007) American Journal of Cardiology , vol.100 , Issue.5 , pp. 899-904
    • O'Keefe, J.H.1    Bell, D.S.H.2
  • 7
    • 0031032831 scopus 로고    scopus 로고
    • Simvastatin, an HMG-coenzyme a reductase inhibitor, improves endothelial function within 1 month
    • O'Driscoll G, Green D, Tayor RR. Simvastatin, an HMG-Coenzyme A reductase inhibitor, improves endothelial function within 1 month. Circulation 1997; 95: 1126-1131. (Pubitemid 27097821)
    • (1997) Circulation , vol.95 , Issue.5 , pp. 1126-1131
    • O'Driscoll, G.1    Green, D.2    Taylor, R.R.3
  • 9
    • 0035572718 scopus 로고    scopus 로고
    • Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
    • Takemoto M, Liao JK. Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol 2001; 21: 1712-1719. (Pubitemid 34219772)
    • (2001) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.21 , Issue.11 , pp. 1712-1719
    • Takemoto, M.1    Liao, J.K.2
  • 10
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia: West of Scotland Coronary Prevention Study Group
    • Shepherd J, Cobbe SM, Ford I, Isles CG, Lorimer AR, MacFarlane PW, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia: West of Scotland Coronary Prevention Study Group. N Engl J Med 1995; 333: 1301-1307.
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3    Isles, C.G.4    Lorimer, A.R.5    MacFarlane, P.W.6
  • 11
    • 33748952489 scopus 로고    scopus 로고
    • Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): A prospective randomised controlled trial
    • MEGA Study Group
    • Nakamura H, Arakawa K, Itakura H, Kitabatake A, Goto Y, Toyota T, et al; MEGA Study Group. Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): A prospective randomised controlled trial. Lancet 2006; 368: 1155-1163.
    • (2006) Lancet , vol.368 , pp. 1155-1163
    • Nakamura, H.1    Arakawa, K.2    Itakura, H.3    Kitabatake, A.4    Goto, Y.5    Toyota, T.6
  • 12
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study Group
    • Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S). Lancet 1994; 344: 1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 13
    • 0037015288 scopus 로고    scopus 로고
    • Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: Effects of short- And long-term simvastatin treatment
    • DOI 10.1161/01.CIR.0000027569.76671.A8
    • Ceriello A, Taboga C, Tonutti L, Quagliaro L, Piconi L, Bais B, et al. Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: Effects of short- and long-term simvastatin treatment. Circulation 2002; 106: 1211-1218. (Pubitemid 34988638)
    • (2002) Circulation , vol.106 , Issue.10 , pp. 1211-1218
    • Ceriello, A.1    Taboga, C.2    Tonutti, L.3    Quagliaro, L.4    Piconi, L.5    Bais, B.6    Da Ros, R.7    Motz, E.8
  • 14
    • 18844442889 scopus 로고    scopus 로고
    • Effect of atorvastatin and irbesartan, alone and in combination, on postprandial endothelial dysfunction, oxidative stress, and inflammation in type 2 diabetic patients
    • Ceriello A, Assaloni R, Da Ros R, Maier A, Piconi L, Quagliaro L, et al. Effect of atorvastatin and irbesartan, alone and in combination, on postprandial endothelial dysfunction, oxidative stress, and inflammation in type 2 diabetic patients. Circulation 2005; 111: 2518-2524.
    • (2005) Circulation , vol.111 , pp. 2518-2524
    • Ceriello, A.1    Assaloni, R.2    Da Ros, R.3    Maier, A.4    Piconi, L.5    Quagliaro, L.6
  • 15
    • 39749102894 scopus 로고    scopus 로고
    • Comparisons of short- And intermediate-term effects of pitavastatin versus atorvastatin on lipid profiles, fibrinolytic parameter, and endothelial function
    • DOI 10.1016/j.ijcard.2007.01.040, PII S0167527307004391
    • Sakabe K, Fukuda N, Fukuda Y, Wakayama K, Nada T, Morishita S, et al. Comparisons of short- and intermediate-term effects of pitavastatin versus atorvastatin on lipid profiles, fibrinolytic parameter, and endothelial function. Int J Cardiol 2008; 125: 136-138. (Pubitemid 351305417)
    • (2008) International Journal of Cardiology , vol.125 , Issue.1 , pp. 136-138
    • Sakabe, K.1    Fukuda, N.2    Fukuda, Y.3    Wakayama, K.4    Nada, T.5    Morishita, S.6    Shinohara, H.7    Tamura, Y.8
  • 17
    • 0034910492 scopus 로고    scopus 로고
    • Impact of postprandial hypertriglyceridemia on vascular responses in patients with coronary artery disease: Effects of ACE inhibitors and fibrates
    • Bae JH, Bassenge E, Lee HJ, Park KR, Park CG, Park KY, et al. Impact of postprandial hypertriglyceridemia on vascular responses in patients with coronary artery disease: Effects of ACE inhibitors and fibrates. Atherosclerosis 2001; 158: 165-171.
    • (2001) Atherosclerosis , vol.158 , pp. 165-171
    • Bae, J.H.1    Bassenge, E.2    Lee, H.J.3    Park, K.R.4    Park, C.G.5    Park, K.Y.6
  • 18
    • 69049085609 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid (EPA) on hemorheological behavior and endothelial function during postprandial hyperlipidemia and hyperglycemia in patients with stable effort angina pectoris
    • in Japanese
    • Umemoto T, Yasu T, Arao K, Ishida T, Ikeda N, Kubo N, et al. Effects of eicosapentaenoic acid (EPA) on hemorheological behavior and endothelial function during postprandial hyperlipidemia and hyperglycemia in patients with stable effort angina pectoris. Jichi Med School J 2005; 28: 51-62 (in Japanese).
    • (2005) Jichi Med School J , vol.28 , pp. 51-62
    • Umemoto, T.1    Yasu, T.2    Arao, K.3    Ishida, T.4    Ikeda, N.5    Kubo, N.6
  • 21
    • 0026673875 scopus 로고
    • Optically accessible microchannels formed in a single-crystal silicon substrate for studies of blood rheology
    • Kikuchi Y, Sato K, Ohki H, Kaneko T. Optically accessible microchannels formed in a single-crystal silicon substrate for studies of blood rheology. Microvasc Res 1992; 44: 226-240.
    • (1992) Microvasc Res , vol.44 , pp. 226-240
    • Kikuchi, Y.1    Sato, K.2    Ohki, H.3    Kaneko, T.4
  • 22
    • 3142755599 scopus 로고    scopus 로고
    • Contribution of fluid shear response in leukocytes to hemodynamic resistance in the spontaneously hypertensive rat
    • DOI 10.1161/01.RES.0000133677.77465.38
    • Fukuda S, Yasu T, Kobayashi N, Ikeda N, Schmid-Shönbein GW. Contribution of fluid shear response in leukocytes to hemodynamic resistance in the spontaneously hypertensive rat. Circ Res 2004; 95: 100-108. (Pubitemid 38931841)
    • (2004) Circulation Research , vol.95 , Issue.1 , pp. 100-108
    • Fukuda, S.1    Yasu, T.2    Kobayashi, N.3    Ikeda, N.4    Schmid-Schonbein, G.W.5
  • 23
    • 0035190665 scopus 로고    scopus 로고
    • A noninvasive measurement of reactive hyperemia that can be used to assess resistance artery endothelial function in humans
    • DOI 10.1016/S0002-9149(00)01288-1, PII S0002914900012991
    • Higashi Y, Sasaki S, Nakagawa K, Matsuura H, Kajiyama G, Oshima T. A noninvasive measurement of reactive hyperemia that can be used to assess resistance artery endothelial function in humans. Am J Cardiol 2001; 87: 121-125. (Pubitemid 32013961)
    • (2001) American Journal of Cardiology , vol.87 , Issue.1 , pp. 121-125
    • Higashi, Y.1    Sasaki, S.2    Nakagawa, K.3    Matsuura, H.4    Kajiyama, G.5    Oshima, T.6
  • 24
  • 25
    • 11144328926 scopus 로고    scopus 로고
    • The postprandial state does not impair endothelial function in women with Type 2 diabetes irrespective of glycaemic control
    • DOI 10.1007/s00125-004-1534-0
    • Strey CH, Young J, Collier M, Florkowski CM, Shand BI, Scott RS. The postprandial state does not impair endothelial function in women with type 2 diabetes irrespective of glycaemic control. Diabetologia 2004; 47: 1838-1846. (Pubitemid 40022421)
    • (2004) Diabetologia , vol.47 , Issue.10 , pp. 1838-1846
    • Strey, C.H.1    Young, J.2    Collier, M.3    Florkowski, C.M.4    Shand, B.I.5    Scott, R.S.6
  • 26
    • 0029977757 scopus 로고    scopus 로고
    • Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance
    • Steinberg HO, Chaker H, Learning R, Johnson A, Brechtel G, Baron AD. Obesity/insulin resistance is associated with endothelial dysfunction: Implications for the syndrome of insulin resistance. J Clin Invest 1996; 97: 2601-2610. (Pubitemid 26187348)
    • (1996) Journal of Clinical Investigation , vol.97 , Issue.11 , pp. 2601-2610
    • Steinberg, H.O.1    Chaker, H.2    Leaming, R.3    Johnson, A.4    Brechtel, G.5    Baron, A.D.6
  • 27
    • 0029789432 scopus 로고    scopus 로고
    • Insulin-stimulated production of nitric oxide is inhibited by Wortmannin: Direct measurement in vascular endothelial cells
    • Zeng G, Quon MJ. Insulin-stimulated production of nitric oxide is inhibited by wortmannin: Direct measurement in vascular endothelial cells. J Clin Invest 1996; 98: 894-898. (Pubitemid 26293305)
    • (1996) Journal of Clinical Investigation , vol.98 , Issue.4 , pp. 894-898
    • Zeng, G.1    Quon, M.J.2
  • 32
    • 0242581695 scopus 로고    scopus 로고
    • Adiponectin Stimulates Production of Nitric Oxide in Vascular Endothelial Cells
    • DOI 10.1074/jbc.M307878200
    • Chen H, Montagnani M, Funahashi T, Shimomura I, Quon MJ. Adiponectin stimulates production of nitric oxide in vascular endothelial cells. J Biol Chem 2003; 278: 45021-45026. (Pubitemid 37377262)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.45 , pp. 45021-45026
    • Chen, H.1    Montagnani, M.2    Funahashi, T.3    Shimomura, I.4    Quon, M.J.5
  • 33
    • 0033613545 scopus 로고    scopus 로고
    • Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin
    • Ouchi N, Kihara S, Arita Y, Maeda K, Kuriyama H, Okamoto Y, et al. Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin. Circulation 1999; 100: 2473-2476.
    • (1999) Circulation , vol.100 , pp. 2473-2476
    • Ouchi, N.1    Kihara, S.2    Arita, Y.3    Maeda, K.4    Kuriyama, H.5    Okamoto, Y.6
  • 35
    • 4644305250 scopus 로고    scopus 로고
    • Circulating adiponectin and resistin levels in relation to metabolic factors, inflammatory markers, and vascular reactivity in diabetic patients and subjects at risk for diabetes
    • DOI 10.2337/diacare.27.10.2450
    • Shetty GK, Economides PA, Horton ES, Mantzoros CS, Veves A. Circulating adiponectin and resistin levels in relation to metabolic factors, inflammatory markers, and vascular reactivity in diabetic patients and subjects at risk for diabetes. Diabetes Care 2004; 27: 2450-2457. (Pubitemid 39281400)
    • (2004) Diabetes Care , vol.27 , Issue.10 , pp. 2450-2457
    • Shetty, G.K.1    Economides, P.A.2    Horton, E.S.3    Mantzoros, C.S.4    Veves, A.5
  • 36
    • 48749131386 scopus 로고    scopus 로고
    • Effects of atorvastatin and pravastatin on glucose tolerance, adipokine levels and inflammatory markers in hypercholesterolaemic patients
    • Ando H, Sugimoto KI, Yanagihara H, Tsuruoka S, Saito T, Takamura T, et al. Effects of atorvastatin and pravastatin on glucose tolerance, adipokine levels and inflammatory markers in hypercholesterolaemic patients. Clin Exp Pharmacol Physiol 2008; 35: 1012-1017.
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , pp. 1012-1017
    • Ando, H.1    Sugimoto, K.I.2    Yanagihara, H.3    Tsuruoka, S.4    Saito, T.5    Takamura, T.6
  • 37
    • 33845985670 scopus 로고    scopus 로고
    • Differential impact of atorvastatin vs pravastatin on progressive insulin resistance and left ventricular diastolic dysfunction in a rat model of type II diabetes
    • DOI 10.1253/circj.71.144
    • Chen Y, Ohmori K, Mizukawa M, Yoshida J, Zeng Y, Zhang L, et al. Differential impact of atorvastatin vs pravastatin on progressive insulin resistance and left ventricular diastolic dysfunction in a rat model of type II diabetes. Circ J 2007; 71: 144-152. (Pubitemid 46045564)
    • (2007) Circulation Journal , vol.71 , Issue.1 , pp. 144-152
    • Chen, Y.1    Ohmori, K.2    Mizukawa, M.3    Yoshida, J.4    Zeng, Y.5    Zhang, L.6    Shinomiya, K.7    Kosaka, H.8    Kohno, M.9
  • 38
    • 25444506344 scopus 로고    scopus 로고
    • Plasma adiponectin, body mass index, and mortality in patients with chronic heart failure
    • DOI 10.1161/CIRCULATIONAHA.104.530972
    • Kistorp C, Faber J, Galatius S, Gustafsson F, Frystyk J, Flyvbjerg A, et al. Plasma adiponectin, body mass index, and mortality in patients with chronic heart failure. Circulation 2005; 112: 1756-1762. (Pubitemid 41372115)
    • (2005) Circulation , vol.112 , Issue.12 , pp. 1756-1762
    • Kistorp, C.1    Faber, J.2    Galatius, S.3    Gustafsson, F.4    Frystyk, J.5    Flyvbjerg, A.6    Hildebrandt, P.7
  • 39
    • 34547179430 scopus 로고    scopus 로고
    • Circulating adiponectin levels and mortality in elderly men with and without cardiovascular disease and heart failure
    • DOI 10.1001/archinte.167.14.1510
    • Wannamethee SG, Whincup PH, Lennon L, Sattar N. Circulating adiponectin levels and mortality in elderly men with and without cardiovascular disease and heart failure. Arch Intern Med 2007; 167: 1510-1517. (Pubitemid 47124181)
    • (2007) Archives of Internal Medicine , vol.167 , Issue.14 , pp. 1510-1517
    • Wannamethee, S.G.1    Whincup, P.H.2    Lennon, L.3    Sattar, N.4
  • 42
    • 33845875499 scopus 로고    scopus 로고
    • Vascular lipotoxicity: Endothelial dysfunction via fatty-acid-induced reactive oxygen species overproduction in obese Zucker diabetic fatty rats
    • DOI 10.1210/en.2006-1132
    • Chinen I, Shimabukuro M, Yamakawa K, Higa N, Matsuzaki T, Noguchi K, et al. Vascular lipotoxicity: Endothelial dysfunction via fatty-acid-induced reactive oxygen species overproduction in obese Zucker diabetic fatty rats. Endocrinology 2007; 148: 160-165. (Pubitemid 46021448)
    • (2007) Endocrinology , vol.148 , Issue.1 , pp. 160-165
    • Chinen, I.1    Shimabukuro, M.2    Yamakawa, K.3    Higa, N.4    Matsuzaki, T.5    Noguchi, K.6    Ueda, S.7    Sakanashi, M.8    Takasu, N.9
  • 43
    • 37849037393 scopus 로고    scopus 로고
    • Pitavastatin, an HMG-CoA reductase inhibitor, exerts eNOS-independent protective actions against angiotensin II induced cardiovascular remodeling and renal insufficiency
    • Yagi S, Aihara K, Ikeda Y, Sumitomo Y, Yoshida S, Ise T, et al. Pitavastatin, an HMG-CoA reductase inhibitor, exerts eNOS-independent protective actions against angiotensin II induced cardiovascular remodeling and renal insufficiency. Circ Res 2008; 102: 68-76.
    • (2008) Circ Res , vol.102 , pp. 68-76
    • Yagi, S.1    Aihara, K.2    Ikeda, Y.3    Sumitomo, Y.4    Yoshida, S.5    Ise, T.6
  • 45
    • 0035569562 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species
    • Wassmann S, Laufs U, Baumer AT, Muller K, Ahlbory K, Linz W, et al. HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species. Hypertension 2001; 37: 1450-1457. (Pubitemid 34225391)
    • (2001) Hypertension , vol.37 , Issue.6 , pp. 1450-1457
    • Wassmann, S.1    Laufs, U.2    Baumer, A.T.3    Muller, K.4    Ahlbory, K.5    Linz, W.6    Itter, G.7    Rosen, R.8    Bohm, M.9    Nickenig, G.10
  • 46
    • 0035584083 scopus 로고    scopus 로고
    • Effect of Pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of Pravastatin)
    • DOI 10.1016/S0002-9149(01)02090-2, PII S0002914901020902
    • Masumoto A, Hirooka Y, Hironaga K, Eshima K, Setoguchi S, Egashira K, et al. Effect of pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of pravastatin). Am J Cardiol 2001; 88: 1291-1294. (Pubitemid 33132098)
    • (2001) American Journal of Cardiology , vol.88 , Issue.11 , pp. 1291-1294
    • Masumoto, A.1    Hirooka, Y.2    Hironaga, K.3    Eshima, K.4    Setoguchi, S.5    Egashira, K.6    Takeshita, A.7
  • 49
    • 0031014389 scopus 로고    scopus 로고
    • Single LDL apheresis improves endothelium-dependent vasodilatation in hypercholesterolemic humans
    • Tamai O, Matsuoka H, Itabe H, Wada Y, Kohno K, Imaizumi T. Single LDL apheresis improves endothelium-dependent vasodilatation in hypercholesterolemic humans. Circulation 1997; 95: 76-82. (Pubitemid 27029946)
    • (1997) Circulation , vol.95 , Issue.1 , pp. 76-82
    • Tamai, O.1    Matsuoka, H.2    Itabe, H.3    Wada, Y.4    Kohno, K.5    Imaizumi, T.6
  • 50
    • 0032508533 scopus 로고    scopus 로고
    • Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase
    • DOI 10.1074/jbc.273.37.24266
    • Laufs U, Liao JK. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase. J Biol Chem 1998; 273: 24266-24271. (Pubitemid 28435775)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.37 , pp. 24266-24271
    • Laufs, U.1    Liao, J.K.2
  • 51
    • 14144256390 scopus 로고    scopus 로고
    • Pitavastatin at low dose activates endothelial nitric oxide synthase through PI3K-AKT pathway in endothelial cells
    • DOI 10.1016/j.lfs.2004.12.003
    • Wang J, Tokoro T, Matsui K, Higa S, Kitajima I. Pitavastatin at low dose activates endothelial nitric oxide synthase through PI3K-AKT pathway in endothelial cells. Life Sci 2005; 76: 2257-2268. (Pubitemid 40283650)
    • (2005) Life Sciences , vol.76 , Issue.19 , pp. 2257-2268
    • Wang, J.1    Tokoro, T.2    Matsui, K.3    Higa, S.4    Kitajima, I.5
  • 55
    • 0032819745 scopus 로고    scopus 로고
    • Reduction of platelet activity markers in Type II hypercholesterolemic patients by a HMG-CoA-reductase inhibitor
    • DOI 10.1016/S0049-3848(99)00037-7, PII S0049384899000377
    • Huhle G, Abletshauser C, Mayer N, Weidinger G, Harenberg J, Heene DL. Reduction of platelet activity markers in type II hypercholesterolemic patients by a HMG-CoA-reductase inhibitor. Thromb Res 1999; 95: 229-234. (Pubitemid 29428154)
    • (1999) Thrombosis Research , vol.95 , Issue.5 , pp. 229-234
    • Huhle, G.1    Abletshauser, C.2    Mayer, N.3    Weidinger, G.4    Harenberg, J.5    Heene, D.L.6


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