Efficient milp formulations for the simultaneous optimal peptide tag design and downstream processing synthesis

AIChE Journal

Volumn 55, Issue 9, 2009, Pages 2303-2317

  Natali, João M ^a   Pinto, José M ^a,c   Papageorgiou, Lazaros G ^b  

^a JACOBS ENGINEERING   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c PRAXAIR INC   (United States)

Author keywords

Bioprocess synthesis; Chromatographic techniques; Mixed integer linear optimization; Piecewise linear approximation; Protein purification; Purification tags

Indexed keywords

BIOPROCESS SYNTHESIS; CHROMATOGRAPHIC TECHNIQUES; MIXED INTEGER LINEAR OPTIMIZATION; PIECEWISE LINEAR APPROXIMATION; PROTEIN PURIFICATION; PURIFICATION TAGS;

AMINES; INTEGER PROGRAMMING; OPTIMIZATION; PEPTIDES; PURIFICATION; SIZE SEPARATION;

PIECEWISE LINEAR TECHNIQUES;

POLYGALA INCARNATA;

EID: 69049101579     PISSN: 00011541     EISSN: 15475905     Source Type: Journal    
DOI: 10.1002/aic.11913     Document Type: Article

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