Activation of the histaminergic H3 receptor induces phosphorylation of the Akt/GSK-3β pathway in cultured cortical neurons and protects against neurotoxic insults

Journal of Neurochemistry

Volumn 110, Issue 5, 2009, Pages 1469-1478

  Mariottini, Chiara ^a   Scartabelli, Tania ^a   Bongers, Gerold ^b   Arrigucci, Silvia ^a   Nosi, Daniele ^c   Leurs, Rob ^b   Chiarugi, Alberto ^a   Blandina, Patrizio ^a   Pellegrini Giampietro, Domenico E ^a   Beatrice Passani, Maria ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c Dipartimento di Anatomia Istologia e Medicina Legale   (Italy)

Author keywords

Apoptosis; Bcl 2; Excitotoxicity; Immepip; Neuroprotection

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA METHYLHISTAMINE; CASPASE 3; GLYCOGEN SYNTHASE KINASE 3BETA; HISTAMINE H3 RECEPTOR; HISTAMINE H3 RECEPTOR AGONIST; IMMEPIP; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE; THIOPERAMIDE; UNCLASSIFIED DRUG; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HISTAMINE AGONIST; NEUROPROTECTIVE AGENT; PROTEIN KINASE B;

ANIMAL CELL; ARTICLE; BRAIN CELL; CELL CULTURE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; WESTERN BLOTTING; ANIMAL; BRAIN CORTEX; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM DISEASE; COMPARATIVE STUDY; DRUG EFFECT; ENZYMOLOGY; METABOLISM; NERVE CELL; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM DISEASES; CEREBRAL CORTEX; GLYCOGEN SYNTHASE KINASE 3; HISTAMINE AGONISTS; MICE; NEURONS; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, HISTAMINE H3; SIGNAL TRANSDUCTION;

EID: 68949199774     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06249.x     Document Type: Article

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