Age-related Macular Degeneration and Cardiovascular Disease in the Era of Anti-Vascular Endothelial Growth Factor Therapies

American Journal of Ophthalmology

Volumn 148, Issue 3, 2009, Pages 327-329

  Wong, Tien Y ^a  

^a CENTRE FOR EYE RESEARCH AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; CHOLESTEROL; PEGAPTANIB; PLACEBO; RANIBIZUMAB; STEROID; VASCULOTROPIN;

ARTERY THROMBOSIS; ATHEROSCLEROSIS; ATTRIBUTABLE RISK; BODY MASS; BRAIN HEMORRHAGE; CANCER PATIENT; CARDIAC PATIENT; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CIGARETTE SMOKING; CLINICAL TRIAL; COMORBIDITY; DISEASE ASSOCIATION; DRUG ABSORPTION; DRUG DOSE COMPARISON; DRUG DOSE REGIMEN; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; EDITORIAL; GASTROINTESTINAL HEMORRHAGE; HIGH RISK PATIENT; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; MORTALITY; NEOPLASM; PATHOGENESIS; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; STROKE; TREATMENT OUTCOME; VENOUS THROMBOEMBOLISM;

ANGIOGENESIS INHIBITORS; CARDIOVASCULAR DISEASES; HUMANS; MACULAR DEGENERATION; RISK FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 68949194750     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajo.2009.05.012     Document Type: Editorial

References (17)

1. Rosenfeld P.J., Brown D.M., Heier J.S., et al. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 355 (2006) 1419-1431
2. Brown D.M., Kaiser P.K., Michels M., et al. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med 355 (2006) 1432-1444
3. Wong T.Y., Liew G., and Mitchell P. Clinical update: new treatments for age-related macular degeneration. Lancet 370 (2007) 204-206
4. Snow K.K., and Seddon J.M. Do age-related macular degeneration and cardiovascular disease share common antecedents?. Ophthalmic Epidemiol 6 (1999) 125-143
5. Klein R., Peto T., Bird A., and VanNewkirk M.R. The epidemiology of age-related macular degeneration. Am J Ophthalmol 137 (2004) 486-495
6. Hogg R.E., Woodside J.V., Gilchrist S.E., et al. Cardiovascular disease and hypertension are strong risk factors for choroidal neovascularization. Ophthalmology 115 (2008) 1046-1052
7. Vingerling J.R., Dielemans I., Bots M.L., Hofman A., Grobbee D.E., and de Jong P.T. Age-related macular degeneration is associated with atherosclerosis. The Rotterdam Study. Am J Epidemiol 142 (1995) 404-409
8. Wong T.Y., Tikellis G., Sun C., Klein R., Couper D.J., and Sharrett A.R. Age-related macular degeneration and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study. Ophthalmology 114 (2007) 86-91
9. Wong T.Y., Klein R., Sun C., et al. Age-related macular degeneration and risk for stroke. Ann Intern Med 145 (2006) 98-106
10. Liao D., Mo J., Duan Y., et al. Is age-related macular degeneration associated with stroke among elderly Americans?. Open Ophthalmol J 2 (2008) 37-42
11. Cugati S., Cumming R.G., Smith W., Burlutsky G., Mitchell P., and Wang J.J. Visual impairment, age-related macular degeneration, cataract and long-term mortality: the Blue Mountains Eye Study. Arch Ophthalmol 125 (2007) 917-924
12. Ferrara N. Role of vascular endothelial growth factor in regulation of physiological angiogenesis. Am J Physiol Cell Physiol 280 (2001) C1358-C1366
13. Nalluri S.R., Chu D., Keresztes R., Zhu X., and Wu S. Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis. JAMA 300 (2008) 2277-2285
14. Bakri S.J., Snyder M.R., Reid J.M., Pulido J.S., and Singh R.J. Pharmacokinetics of intravitreal bevacizumab (Avastin). Ophthalmology 114 (2007) 855-859
15. Gillies M.C., and Wong T.Y. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 356 (2007) 748-749
16. Genentech. Safety Update on Lucentis. 2007. http://www.fda.gov/medwatch/safety/2007/Lucentis_DHCP_01-24-2007.pdf Accessed: March 1, 2009
17. Ciulla T.A., and Rosenfeld P.J. Antivascular endothelial growth factor therapy for neovascular age-related macular degeneration. Curr Opin Ophthalmol 20 (2009) 158-165