Peptide NMHRYPNQ of the Cellular Prion Protein (PrPC) Inhibits Aggregation and Is a Potential Key for Understanding Prion-Prion Interactions

Journal of Molecular Biology

Volumn 392, Issue 1, 2009, Pages 198-207

  Rehders, Dirk ^a   Claasen, Birgit ^a   Redecke, Lars ^a   Buschke, Alexander ^a   Reibe, Caroline ^a   Jehmlich, Nico ^b   von Bergen, Martin ^b   Betzel, Christian ^a   Meyer, Bernd ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

^b HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

Author keywords

aggregation; BSE; NMR binding epitope; surface plasmon resonance

Indexed keywords

OCTAPEPTIDE; PRION PROTEIN; SYNTHETIC PEPTIDE;

ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG RESEARCH; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; INHIBITION KINETICS; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOGENESIS; PRION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SCRAPIE;

EID: 68949178561     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.07.014     Document Type: Article

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