Synthesis and characterization of nanoporous polycaprolactone membranes via thermally- and nonsolvent-induced phase separations for biomedical device application

Journal of Membrane Science

Volumn 343, Issue 1-2, 2009, Pages 180-188

  Yen, Chi ^a   He, Hongyan ^a   Lee, L James ^a   Ho, W S Winston ^a  

^a The Ohio State University   (United States)

Author keywords

Controlled release; Drug delivery; Lysozyme; Nanoporous; Nonsolvent induced phase separation (NIPS); Polycaprolactone (PCL); Thermally induced phase separation (TIPS)

Indexed keywords

CONTROLLED RELEASE; LYSOZYME; NANOPOROUS; NONSOLVENT-INDUCED PHASE SEPARATION (NIPS); POLYCAPROLACTONE (PCL); THERMALLY INDUCED PHASE SEPARATION (TIPS);

COAGULATION; CONTROLLED DRUG DELIVERY; ENZYMES; ETHERS; MEMBRANES; PHASE MODULATION; POLYCAPROLACTONE; SHOTCRETING;

PHASE SEPARATION;

2 METHOXYETHANOL; DIOXANE; LYSOZYME; POLYCAPROLACTONE;

ARTICLE; ARTIFICIAL MEMBRANE; CHEMICAL ANALYSIS; DRUG DELIVERY SYSTEM; ENZYME RELEASE; MEMBRANE PERMEABILITY; NANODEVICE; NANOENGINEERING; POROSITY; PRIORITY JOURNAL; SEPARATION TECHNIQUE; THERMOSTABILITY;

EID: 68949172257     PISSN: 03767388     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.memsci.2009.07.024     Document Type: Article

References (43)

1. Moses M.A., Brem H., and Langer R. Advancing the field of drug delivery: Taking aim at cancer. Cancer Cell 4 (2003) 337-341
2. Kisker O., Barucel S., Rak J., Man S., Clark K., Hicklin D.J., Bohlen P., and Kerbel R.S. Continuous administration of endostatin by intraperitoneally implanted osmotic pump improve the efficacy and potency of therapy in a mouse xenograft tumor model. Cancer Res. 61 (2001) 7669-7674
3. Langer R. Perspectives: drug delivery-drug on target. Science 293 (2001) 58-59
4. Lee L.J. Polymer nanoengineering for biomedical applications. Ann. Biomed. Eng. 34 (2006) 75-88
5. Mi F.L., Wu Y.B., Shyu S.S., Chao A.C., Lai J.Y., and Su C.C. Asymmetric chitosan membranes prepared by dry/wet phase separation: a new type of wound dressing for controlled antibacterial release. J. Membr. Sci. 212 (2003) 237-254
6. Qian F., Nasongkla N., and Gao J. Membrane-encased polymer millirods for sustained release of 5-fluorouracil. J. Biomed. Mater. Res. 61 (2002) 203-211
7. McHugh A.J. The role of polymer membrane formation in sustained release drug delivery system. J. Control. Release 109 (2005) 211-221
8. Meier M.M., Kanis L., and Soldi V. Characterization and drug-permeation profiles of microporous and dense cellulose acetate membranes: influence of plasticizer and pore forming agent. Int. J. Pharm. 278 (2004) 99-110
9. Altinkaya S.A., and Yenal H. In vitro drug release rates from asymmetric-membrane tablet coatings: Prediction of phase-inversion dynamics. Biochem. Eng. J. 28 (2006) 131-139
10. Martin F., Walczak R., Boiarski A., Cohen M., West T., Cosentino C., and Ferrari M. Tailoring width of microfabricated nanochannels to solute size can be used to control diffusion kinetics. J. Control. Release 102 (2005) 123-133
11. Desai T.A., Hansford D., and Ferrari M. Nanopore technology for biomedical applications. Biomed. Microdevices 2 (1999) 11-40
12. Berg M.C., Zhai L., Cohen R.E., and Rubner M.F. Controlled drug release from porous polyelectrolyte multilayers. Biomacromolecules 7 (2006) 357-364
13. 2 membranes. J. Membr. Sci. 319 (2008) 199-205
14. Desai T.A., Hansford D., and Ferrari M. Characterization of micromachnined silicon membranes for immunoisolation and bioseparation applications. J. Membr. Sci. 159 (1999) 221-231
15. Cosentino C., Amato F., Walczak R., Boiarski A., and Ferrari M. Dynamic model of biomolecular diffusion through two-dimension nanochannels. J. Phys. Chem. B 109 (2005) 7358-7364
16. Amato F., Cosentino C., Pricl S., Ferrone M., Fermeglia M., Cheng M.M.C., Walczak R., and Ferrari M. Multiscale modeling of protein transport in silicon membrane nanochannels: Part 2. From molecular parameters to a predictive continuum diffusion model. Biomed. Microdevices 8 (2006) 291-298
17. LaVan A.D., McGuire T., and Langer R. Small-scale systems for in vivo drug delivery. Nat. Biotechnol. 21 (2003) 1184-1191
18. Zhang X., He H., Yen C., Ho W.S.W., and Lee L.J. A biodegradable, immunoprotective, dual nanoporous capsule for cell-based therapies. Biomaterials 29 (2008) 4253-4259
19. Grayson A.C.R., Shawgo R.S., Johnson A.M., Flynn N.T., Li Y., Cima M.J., and Langer R. A BioMEMS review: MEMS technology for physiologically integrated devices. Proc. IEEE 92 (2004) 6-21
20. flame K.E.L., Popat K.C., Leoni L., Markiewicz E., Tempa T.J.L., Roman B.B., Grimes C.A., and Desi T.A. Biocompatibility of nanoporous alumina membranes for immunoisolation. Biomaterials 28 (2007) 2638-2645
21. Lin W.J., and Lu C.H. Characterization and permeation of microporous poly(ε- caprolactone) films. J. Membr. Sci. 198 (2002) 109-118
22. Lin W.J., and Lee H.G. Design of a microporous controlled delivery system for theophylline tablets. J. Control. Release 89 (2003) 179-187
23. Tiaw K.S., Teoh S.H., Chen R., and Hong M.H. Processing methods of ultrathin poly(ε-caprolactone) films for tissue engineering applications. Biomacromolecules 8 (2007) 807-816
24. Khor H.L., Ng K.W., Htay A.S., Schantz J.T., Teoh S.H., and Hutmachies D.W. Preliminary study of a polycaprolactone membrane utilized as epidermal substrate. J. Mater. Sci. Mater. Med. 14 (2003) 113-120
25. Tanaka T., Tsuchiya T., Takahashi H., Taniguchi M., and Lloyd D.R. Microfiltration membrane of polymer blend of poly(L-lactic acid) and poly(ε-caprolactone). Desalination 1993 (2006) 367-374
26. Takana T., Tsuchiya T., Takahashi H., Taniguchi M., Ohara H., and Lloyd D.R. Formation of biodegradable polyester membranes via thermally induced phase separation. J. Chem. Eng. Jpn. 39 (2006) 144-153
27. Chiang H.I., Perrie Y., and Coombes A.G.A. Delivery of the antibiotic gentamicin sulphate from precipitation cast matrices of polycaprolactone. J. Control. Release 110 (2006) 414-421
28. Coombes A.G.A., Rizzi S.C., Williamson M., Barralet J.E., Downes S., and Wallace W.A. Precipitation casting of polycaprolactone for applications in tissue engineering and drug delivery. Biomaterials 25 (2004) 315-325
29. Wang Y., Chang H.I., Wertheim D.F., Jones A.S., Jackson C., and Coombes A.G.A. Characterization of the macroporosity of polycaprolactone-based biocomposites and release kinetics for drug delivery. Biomaterials 28 (2007) 4619-4627.29
30. Tanaka M., Takebayashi M., Miyama M., Nishida J., and Shimomura M. Design of novel biointerfaces (II). Fabrication of self-organized porous polymer film with highly uniform pores. Bio-Med. Mater. Eng. 14 (2004) 439-446
31. Yamamoto S., Tanaka M., Sunami H., Arai K., Takayama A., Yamashita S., Morita Y., and Shimomura M. Relationship between adsorbed fibronectin and cell adhesion on a honey- comb patterned film. Surf. Sci. 600 (2006) 3785-3791
32. Ma W., Zhang J., and Wang X. Crystallization and surface morphology of poly(vinylidene fluoride)/(poly(methylmethacrylate) films by solution casting on different substrates. Appl. Surf. Sci. 254 (2008) 2947-2954
33. Zeng M., Zhang L., and Zhou Y. Effects of solid substrate on structure and properties of casting waterborne polyurethane/carboxymethylchitin films. Polymer 45 (2004) 3535-3545
34. Aerts P., Genn I., Leysen R., Jacobs P.A., and Vankelecom I.F.J. The role of the nature of the casting substrate on the properties of membranes prepared via immersion precipitation. J. Membr. Sci. 283 (2006) 320-327
35. Haas C.K., and Torkelson J.M. Two-dimensional coarsening and phase separation in thin polymer solution films. Phys. Rev. E 55 (1997) 3191-3201
36. In: Ho W.S.W., and Sirkar K.K. (Eds). Membrane Handbook (1992), Chapman & Hall, New York (Kluwer Academic Publishers, Boston, Reprint Edition, 2001)
37. van den Witte P., Esselbrugge H., Dijkstra P.J., van den Berg J.W.A., and Feijen J. A morphological study of membranes obtained from the systems polylactide-dioxane-methanol, polylactide-dioxane-water, and polylactide-N-methyl pyrrolidone-water. J. Polym. Sci. B: Polym. Phys. 34 (1996) 2569-2578
38. Graham P.D., and McHugh A.J. Kinetics of thermally induced phase separation in a crystallizable polymer solution. Macromolecules 31 (1998) 2565-2568
39. Binder K., and Stauffer D. Theory for slowing down of relaxation and spinodal decomposition of binary-mixtures. Phys. Rev. Lett. 33 (1974) 1006-1009
40. Lifshitz I.M., and Slyozov V.V.J. The kinetics of precipitation from supersaturated solutions. Phys. Chem. Solids 19 (1961) 35-50
41. Crist B. On "pinning" domain growth in two-phase polymer liquids. Macromolecules 29 (1996) 7276-7279
42. Hellman D.J., Greenberg A.R., and Krantz W.B. A novel process for membrane fabrication: thermally assisted evaporative phase separation (TAEPS). J. Membr. Sci. 230 (2004) 99-109
43. Tanaka T., Tsuchiya T., Takahashi H., Taniguchi M., Ohara H., and Lloyd D.R. Formation of biodegradable polyesters membranes via thermally induced phase separation. J. Chem. Eng. Jpn. 39 (2006) 144-153