Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic guanine nucleotide exchange activity

PLoS ONE

Volumn 4, Issue 8, 2009, Pages

  Miletic, Ana V ^a   Graham, Daniel B ^a   Sakata Sogawa, Kumiko ^b   Hiroshima, Michio ^b   Hamann, Michael J ^c   Cemerski, Saso ^a   Kloeppel, Tracie ^a   Billadeau, Daniel D ^c   Kanagawa, Osami ^b   Tokunaga, Makio ^b,d   Swat, Wojciech ^a  

^a USA   (United States)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

^c MAYO GRADUATE SCHOOL   (United States)

^d GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN VAV1; RAC1 PROTEIN; T LYMPHOCYTE RECEPTOR; TYROSINE; UNCLASSIFIED DRUG; VAV PROTEIN; BIOPOLYMER; LYMPHOCYTE ANTIGEN RECEPTOR; VAV1 PROTEIN, MOUSE;

ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY COMBINING SITE; ARTICLE; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL FUNCTION; CELL MATURATION; CELL PROLIFERATION; CELL SPREADING; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOSKELETON; ENZYME ACTIVITY; GENE ACTIVATION; HUMAN; HUMAN CELL; MICROTUBULE ORGANIZING CENTER; MOLECULAR IMAGING; MOUSE; NONHUMAN; POLARIZATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION INITIATION; TRANSCRIPTION INITIATION SITE; ANIMAL; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MOUSE MUTANT; PHYSIOLOGY; T LYMPHOCYTE;

ACTINS; ANIMALS; BIOPOLYMERS; CYTOSKELETON; GUANINE NUCLEOTIDE EXCHANGE FACTORS; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS C-VAV; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 68949163905     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006599     Document Type: Article

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