Stereoselective HPLC assay of TJ0711 enantiomers by precolumn derivatization with GITC using UV detection and its application in pharmacokinetics in rats

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 29, Issue 4, 2009, Pages 427-430

  Sun, Shuping ^a   Si, Luqin ^a   Fan, Zhaoze ^a   Qiu, Jun ^a   Li, Gao ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Enantiomers; GITC; HPLC; Pharmacokinetics; Stereoselective; TJ0711

Indexed keywords

1 (4 (2 METHOXYETHYL)PHENOXY) 3 (((2 2 METHOXYPHENOXY)ETHYL)AMINO) 2 PROPANOL; 1-(4-(2-METHOXYETHYL)PHENOXY)-3-(((2-2-METHOXYPHENOXY)ETHYL)AMINO)-2-PROPANOL; 2,3,4,6 TETRA O ACETYLGLUCOPYRANOSYLISOTHIOCYANATE; 2,3,4,6-TETRA-O-ACETYLGLUCOPYRANOSYLISOTHIOCYANATE; ADRENERGIC RECEPTOR BLOCKING AGENT; ISOTHIOCYANIC ACID DERIVATIVE; PHENOXYPROPANOLAMINE DERIVATIVE;

ANIMAL; ARTICLE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; METHODOLOGY; RAT; SPRAGUE DAWLEY RAT; STEREOISOMERISM; ULTRAVIOLET SPECTROPHOTOMETRY;

ADRENERGIC ANTAGONISTS; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ISOTHIOCYANATES; MALE; PHENOXYPROPANOLAMINES; RATS; RATS, SPRAGUE-DAWLEY; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM;

EID: 68949144479     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-009-0407-7     Document Type: Article

References (20)

1. J. Caldwell 1992 The important of stereochemistry in drug action and disposition J Clin Pharmacol 32 10 925 929
2. R.L. Nation 1994 Chirality in new drug development: Clinical pharmacokinetic considerations Clin Pharmacokinet 27 4 249 255
3. M. Eichelbaum 1998 Pharmacokinetic and pharmacodynamic consequences of stereoselective drug metabolism in man Biochem Pharmacol 37 1 93 96
4. F. Jamali R. Mehvar F.M. Pasutto 1989 Enantioselective aspects of drug action and disposition:therapeutic pitfalls J Pharm Sci 78 9 695 715
5. Caldwell J. 'Chiral pharmacology' and the regulation of new drugs. Chem Ind, 1995(3):176-179
6. J. Martens R. Bhushan 1992 Resolution of enantiomers with achiral phase chromatography J Liq Chromatogr 15 1 1 27
7. K.H. Kim S.Y. Heo S.P. Hong 2000 Enantiomeric purity test of bevantolol by reversed-phase high performance liquid chromatography after derivatization with 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl isothiocyanate Arch Pharm Res 23 6 568 573
8. K.H. Kim D.S. Kim S.P. Hong 2000 Reversed-phase high performance liquid chromatographic separation of the enantiomers of terbutaline by derivatization with 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl isothiocyanate Arch Pharm Res 23 1 26 30
9. E. Yang S. Wang J. Kratz 2004 Stereoselective analysis of carvedilol in human plasma using HPLC/MS/MS after chiral derivatization J Pharm Biomed Anal 36 3 609 615
10. Y.H. Tang Y. He T.W. Yao 2004 Simultaneous determination of the enantiomers of esmolol and its acid metabolite in human plasma by reversed phase liquid chromatography with solid-phase extraction J Chromatogr B 805 2 249 254
11. S. Hess K.R. Gustafson D.J. Milanowski 2004 Chirality determination of unusual amino acids using precolumn derivatization and liquid chromatography-electrospray ionization mass spectrometry J Chromatogr A 1035 2 211 219
12. D. Braghiroli M.D. Bella 1996 Asymmetric syntheses of (R)-and (S)-2-aminobutanesulfonic acid and their 3, 3-dimethylderivatives Tetrahedron: Asymmetry 7 7 2145 2150
13. Q. Zhou T.W. Yao S. Zeng 2002 Chiral reversed phase high-performance liquid chromatography for determining propranolol enantiomers in transgenic Chinese hamster CHL cell lines expressing human cytochrome P450 J Biochem Biophys Meth 54 1-3 369 376
14. D. Jin A.P. Kumar G.C. Song 2008 Determination of thyroxine enantiomers in pharmaceutical formulation by high-performance liquid chromatography-mass spectrometry with precolumn derivatization Microchem J 88 1 62 66
15. M.G. Chernobrovkin E.N. Shapovalova D.T. Guranda 2007 Chiral high-performance liquid chromatography analysis of α-amino acid mixtures using a novel SH reagent-N-R-mandelyl-l-cysteine and traditional enantiomeric thiols for precolumn derivatization J Chromatogr A 1175 1 89 95
16. N. Unceta S. Barrondo I.R. de Azúa 2007 Determination of fluoxetine, norfluoxetine and their enantiomers in rat plasma and brain samples by liquid chromatography with fluorescence detection J Chromatogr B 852 1-2 519 528
17. N. Nimura T. Fujiwara A. Watanabe 2003 A novel chiral thiol reagent for automated precolumn derivatization and high-performance liquid chromatographic enantioseparation of amino acids and its application to the aspartate racemase assay Anal Biochem 315 2 262 269
18. Y. Hori M. Fujisawa K. Shimada 2002 Enantioselective analysis of glufosinate using precolumn derivatization with (+)-1-(9-fluorenyl)ethyl chloroformate and reversed-phase liquid chromatography J Chromatogr B 776 2 191 198
19. C. Gunaratna P.T. Kissinger 1998 Investigation of stereoselective metabolism of amphetamine in rat liver microsomes by microdialysis and liquid chromatography with precolumn chiral derivatization J Chromatogr A 828 1-2 95 103
20. T.A.C. Vermeij P.M. Edelbroek 1998 High-performance liquid chromatographic analysis of vigabatrin enantiomers in human serum by precolumn derivatization with O-phthaldialdehyde-N-acetyl-L-cysteine and fluorescence detection J Chromatogr B 716 1-2 233 238