Flow cytometric detection of platelet-associated immunoglobulin in patients with immune thrombocytopenic purpura and nonimmune thrombocytopenia

Annals of Clinical and Laboratory Science

Volumn 39, Issue 3, 2009, Pages 283-288

  Huh, Hee Jin ^a,b   Chan, Jeoung Park ^a   Sang, We Kim ^a   Sang, Hee Han ^a   Jang, Seongsoo ^a   Hyun, Sook Chi ^a  

^a University of Ulsan   (South Korea)

^b Dongguk University College of Medicine   (South Korea)

Author keywords

Flow cytometry; Immune thrombocytopenic purpura; Platelet associated immunoglobulin

Indexed keywords

IMMUNOGLOBULIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; PLATELET ASSOCIATED IMMUNOGLOBULIN; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD SAMPLING; CHILD; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; FEMALE; FLOW CYTOMETRY; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; INFANT; LIVER DISEASE; MAJOR CLINICAL STUDY; MALE; MYELODYSPLASTIC SYNDROME; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY; THROMBOCYTE; THROMBOCYTE COUNT; THROMBOCYTOPENIA;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BLOOD PLATELETS; CHILD; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOGLOBULINS; INFANT; MALE; MIDDLE AGED; PLATELET COUNT; PREDICTIVE VALUE OF TESTS; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; ROC CURVE; SENSITIVITY AND SPECIFICITY; SERUM GLOBULINS; THROMBOCYTOPENIA;

EID: 68949131168     PISSN: 00917370     EISSN: 15508080     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. George JN, Woolf SH, Raskob GE, Wasser JS, Aledort LM, Ballem PJ, Blanchette VS, Bussel JB, Cines DB, Kelton JG, Lichtin AE, McMillan R, Okerbloom JA, Regan DH, Warrier I. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood 1996;88:3-40. (Pubitemid 26230668)
2. Berchtold P, Muller D, Beardsley D, Fujisawa K, Kaplan C, Kekomaki R, Lipp E, Morell-Kopp MC, Kiefel V, McMillan R, von dem Borne AE, Imbach P. International study to compare antigen-specific methods used for the measurement of antiplatelet autoantibodies. Br J Haematol 1997;96:477-483. (Pubitemid 27087230)
3. von dem Borne AE, Vos JJ, van der Lelie J, Bossers B, van Dalen CM. Clinical significance of positive platelet immunofluorescence test in thrombocytopenia. Br J Haematol 1986;64:767-776.
4. Hagenstrom H, Schlenke P, Hennig H, Kirchner H, Kluter H. Quantification of platelet-associated IgG for differential diagnosis of patients with thrombocytopenia. Thromb Haemost 2000;84:779-783. (Pubitemid 30946936)
5. Kelton JG. The measurement of platelet-bound immunoglobulins: an overview of the methods and the biological relevance of platelet-associated IgG. Prog Hematol 1983;13:163-199.
6. Rosenfeld CS, Nichols G, Bodensteiner DC. Flow cytometric measurement of antiplatelet antibodies. Am J Clin Pathol 1987;87:518-522. (Pubitemid 17050227)
7. Romero-Guzman LT, Lopez-Karpovitch X, Paredes R, Barrales-Benitez O, Piedras J. Detection of platelet-associated immunoglobulins by flow cytometry for the diagnosis of immune thrombocytopenia. Haematologica 2000;85:627-631.
8. Kajihara M, Kato S, Okazaki Y, Kawakami Y, Ishii H, Ikeda Y, Kuwana M. A role of autoantibody-mediated platelet destruction in thrombocytopenia in patients with cirrhosis. Hepatology 2003;37:1267-1276. (Pubitemid 36667305)
9. Kuroda J, Kimura S, Kobayashi Y, Wada K, Uoshima N, Yoshikawa T. Unusual myelodysplastic syndrome with the initial presentation mimicking idiopathic thrombocytopenic purpura. Acta Haematol 2002;108:139-143. (Pubitemid 35316748)
10. Stephan F, Cheffi MA, Kaplan C, Maillet J, Novara A, Fagon J, Bonnet F. Autoantibodies against platelet glycoproteins in critically ill patients with thrombocytopenia. Am J Med 2000;108:554-560. (Pubitemid 30249033)
11. Kelton JG, Powers PJ, Carter CJ. A prospective study of the usefulness of the measurement of platelet-associated IgG for the diagnosis of idiopathic thrombocytopenic purpura. Blood 1982;60:1050-1053.
12. Hezard N, Simon G, Mace C, Jallu V, Kaplan C, Nguyen P. Is flow cytometry accurate enough to screen platelet autoantibodies? Transfusion 2008;48:513-518.
13. Janisiw M, Eichelberger B, Koren D, Panzer S. Screening for platelet auto-antibodies by flow cytometry and their evaluation by the MAIPA technique. Wien Klin Wochenschr 1998;110:531-534. (Pubitemid 28407284)
14. Fabris F, Scandellari R, Randi ML, Carraro G, Luzzatto G, Girolami A. Attempt to improve the diagnosis of immune thrombocytopenia by combined use of two different platelet autoantibodies assays (PAIgG and MACE). Haematologica 2002;87:1046-1052. (Pubitemid 35192216)
15. Javela K, Kekomaki R. Mean platelet size related to glycoprotein-specific autoantibodies and platelet-associated IgG. Int J Lab Hematol 2007;29:433-441. (Pubitemid 350060623)
16. Christopoulos CG, Kelsey HC, Machin SJ. A flowcytometric approach to quantitative estimation of platelet surface immunoglobulin G. Vox Sang 1993;64:106-115.
17. Tazzari PL, Ricci F, Vianelli N, Tassi C, Belletti D, Pierri I, Gugliotta L, Gobbi M, Conte R. Detection of platelet-associated antibodies by flow cytometry in hematological autoimmune disorders. Ann Hematol 1995;70:267-272.
18. Beardsley DS, Ertem M. Platelet autoantibodies in immune thrombocytopenic purpura. Transfus Sci 1998;19:237-244. (Pubitemid 128452064)
19. George JN. Platelet immunoglobulin G: its significance for the evaluation of thrombocytopenia and for understanding the origin of alpha-granule proteins. Blood 1990;76:859-870.
20. Warner M, Kelton JG. Laboratory investigation of immune thrombocytopenia. J Clin Pathol 1997;50:5-12.
21. Brighton TA, Evans S, Castaldi PA, Chesterman CN, Chong BH. Prospective evaluation of the clinical usefulness of an antigen-specific assay (MAIPA) in idiopathic thrombocytopenic purpura and other immune thrombocytopenias. Blood 1996;88:194-201. (Pubitemid 26230687)
22. Feistauer SM, Penner E, Mayr WR, Panzer S. Target platelet antigens of autoantibodies in patients with primary biliary cirrhosis. Hepatology 1997;25:1343-1345. (Pubitemid 27250751)
23. Sanjo A, Satoi J, Ohnishi A, Maruno J, Fukata M, Suzuki N. Role of elevated platelet-associated immunoglobulin G and hypersplenism in thrombocytopenia of chronic liver diseases. J Gastroenterol Hepatol 2003;18:638-644. (Pubitemid 36791700)
24. Giannouli S, Voulgarelis M, Zintzaras E, Tzioufas AG, Moutsopoulos HM. Autoimmune phenomena in myelodysplastic syndromes: a 4-year prospective study. Rheumatology (Oxford) 2004;43:626-632. (Pubitemid 38628195)