Predictors and Impact of Bleeding Complications in Percutaneous Coronary Intervention, Acute Coronary Syndromes, and ST-Segment Elevation Myocardial Infarction

American Journal of Cardiology

Volumn 104, Issue 5 SUPPL., 2009, Pages 9C-15C

  Manoukian, Steven V ^a  

^a SARAH CANNON RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; FIBRINOGEN RECEPTOR ANTAGONIST; HEPARIN; HIRULOG; PRASUGREL;

ACUTE CORONARY SYNDROME; ACUTE HEART INFARCTION; AGING; ANTICOAGULANT THERAPY; ANTICOAGULATION; ARTICLE; BLEEDING; BRAIN HEMORRHAGE; CLINICAL DECISION MAKING; CLINICAL TRIAL; CORONARY STENT; DRUG ELUTING STENT; EVIDENCE BASED MEDICINE; HEART CATHETERIZATION; HEART INFARCTION; HEMATOMA; HUMAN; HYPERTENSION; INTRAOCULAR HEMORRHAGE; KIDNEY DISEASE; MORTALITY; OUTCOME ASSESSMENT; PERCUTANEOUS CORONARY INTERVENTION; PREDICTION; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; ST SEGMENT ELEVATION; STENT THROMBOSIS; THROMBOSIS PREVENTION;

EID: 68949092641     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2009.06.020     Document Type: Article

References (17)

1. Stone G.W., McLaurin B.T., Cox D.A., Bertrand M.E., Lincoff A.M., Moses J.W., White H.D., Pocock S.J., Ware J.H., Feit F., et al. Bivalirudin for patients with acute coronary syndromes. N Engl J Med 355 (2006) 2203-2216
2. Wiviott S.D., Braunwald E., McCabe C.H., Montalescot G., Ruzyllo W., Gottlieb S., Neumann F.J., Ardissino D., De Servi S., Murphy S.A., et al., TRITON-TIMI 38 Investigators. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 357 (2007) 2001-2015
3. Grines C.L., Bonow R.O., Casey Jr. D.E., Gardner T.J., Lockhart P.B., Moliterno D.J., O'Gara P., and Whitlow P. Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents: a science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions, American College of Surgeons, and American Dental Association, with representation from the American College of Physicians. Circulation 115 (2007) 813-818
4. Feit F., Voeltz M.D., Attubato M.J., Lincoff A.M., Chew D., Bittl J.A., Topol E.J., and Manoukian S.V. Predictors and impact of major hemorrhage on mortality following percutaneous coronary intervention from the REPLACE-2 trial. Am J Cardiol 100 (2007) 1364-1369
5. Spencer F.A., Moscucci M., Granger C.B., Gore J.M., Goldberg R.J., Steg P.G., Goodman S.G., Budaj A., FitzGerald G., and Fox K.A.A. Does comorbidity account for the excess mortality in patients with major bleeding in acute myocardial infarction?. Circulation 116 (2007) 2793-2801
6. Manoukian S.V., Feit F., Mehran R., Voeltz M.D., Ebrahimi R., Hamon M., Dangas G.D., Lincoff A.M., White H.D., Moses J.W., et al. Impact of major bleeding on 30-day mortality and clinical outcomes in patients with acute coronary syndromes: an analysis from the ACUITY trial. J Am Coll Cardiol 49 (2007) 1362-1368
7. Mehran R., Pocock S.J., Stone G.W., Clayton T.C., Dangas G.D., Feit F., Manoukian S.V., Nikolsky E., Lansky A.J., Kirtane A., et al. Associations of major bleeding and myocardial infarction with the incidence and timing of mortality in patients presenting with non-ST-elevation acute coronary syndromes: a risk model from the ACUITY trial. Eur Heart J 30 (2009) 1457-1466
8. Voeltz M.D., Patel A.D., Feit F., Fazel R., Lincoff A.M., and Manoukian S.V. Effect of anemia on hemorrhagic complications and mortality in patients undergoing percutaneous coronary intervention. Am J Cardiol 99 (2007) 1513-1517
9. Stone G.W., Witzenbichler B., Guagliumi G., Peruga J.Z., Brodie B.R., Dudek D., Kornowski R., Hartmann F., Gersh B.J., Pocock S.J., et al. Bivalirudin during primary PCI in acute myocardial infarction. N Engl J Med 358 (2008) 2218-2230
10. Feit F., Manoukian S.V., Ebrahimi R., Pollack Jr. C.V., Ohman E.M., Attubato M.J., Mehran R., and Stone G.W. Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes: a report from the ACUITY trial. J Am Coll Cardiol 51 (2008) 1645-1652
11. Lopes R.D., Alexander K.P., Manoukian S.V., Bertrand M.E., Feit F., White H.D., Pollack Jr. C.V., Hoekstra J., Gersh B.J., Stone G.W., and Ohman E.M. Advanced age, antithrombotic strategy, and bleeding in non-ST-segment elevation acute coronary syndromes: results from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial. J Am Coll Cardiol 53 (2009) 1021-1030
12. Berger P.B., and Manoukian S.V. Bleeding is bad . . . isn't it?. Circulation 116 (2007) 2776-2778
13. Wang T.Y., Xiao L., Alexander K.P., Rao S.V., Kosiborod M.N., Rumsfeld J.S., Spertus J.A., and Peterson E.D. Antiplatelet therapy use after discharge among acute myocardial infarction patients with in-hospital bleeding. Circulation 118 (2008) 2139-2145
14. Steinhubl S.R., Berger P.B., Brennan D.M., and Topol E.J. Optimal timing for the initiation of pre-treatment with 300 mg clopidogrel before percutaneous coronary intervention. J Am Coll Cardiol 47 (2006) 939-943
15. Kandzari D.E., Berger P.B., Kastrati A., Steinhubl S.R., Mehilli J., Dotzer F., Ten Berg J.M., Neumann F.J., Bollwein H., Dirschinger J., and Schömig A. Influence of treatment duration with a 600-mg dose of clopidogrel before percutaneous coronary revascularization. J Am Coll Cardiol 44 (2004) 2133-2136
16. Hamon M., Rasmussen L.H., Manoukian S.V., Cequier A., Lincoff A.M., Rupprecht H.-J., Gersh B.J., Mann T., Bertrand M.E., Mehran R., and Stone G.W. Choice of arterial access site and outcomes in patients with acute coronary syndromes managed with an early invasive strategy: the ACUITY trial. EuroInterv 5 (2009) 115-120
17. Manoukian S.V., Voeltz M.D., and Eikelboom J. Bleeding complications in acute coronary syndromes and percutaneous coronary intervention: predictors, prognostic significance, and paradigms for reducing risk. Clin Cardiol 10 suppl 2 (2007) II24-II34