Polychlorinated dibenzo-p-dioxins, dibenzofurans and polychlorinated biphenyls levels in human breast milk from different regions of Turkey

Chemosphere

Volumn 76, Issue 11, 2009, Pages 1563-1571

  Çok, Ismet ^a   Donmez, Menekse Keski ^a   Uner, Mine ^b   Demirkaya, Erkan ^c   Henkelmann, Bernhard ^d   Shen, Heqing ^d,e   Kotalik, Jarmila ^d   Schramm, Karl Werner ^d  

^a GAZI UNIVERSITY   (Turkey)

^b AKDENIZ UNIVERSITY   (Turkey)

^c GULHANE SCHOOL OF MEDICINE   (Turkey)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Human breast milk; PCB; PCDD F; Turkey

Indexed keywords

GAS CHROMATOGRAPHY; MASS SPECTROMETRY; POLYCHLORINATED BIPHENYLS;

ENVIRONMENTAL CONTAMINANT; HIGH-RESOLUTION GAS CHROMATOGRAPHY/HIGH-RESOLUTION MASS SPECTROMETRIES; HUMAN BREAST MILKS; PCDD/F; POLYCHLORINATED BIPHENYLS (PCB); POLYCHLORINATED DIBENZO-P-DIOXINS; POLYCHLORINATED DIBENZOFURANS; TURKEY;

ORGANIC POLLUTANTS;

1,2,3,4,6,7,8,9 OCTACHLORODIBENZO 4 DIOXIN; 1,2,3,4,7,8 HEXACHLORODIBENZOFURAN; 2,2',3,4,4',5,5' HEPTACHLOROBIPHENYL; 2,2',4,4',5,5' HEXACHLOROBIPHENYL; 2,3,4,6,7,8 HEXACHLORODIBENZOFURAN; 2,3,4,7,8 PENTACHLORODIBENZOFURAN; 2,4',5 TRICHLOROBIPHENYL; 3,3',4,4',5 PENTACHLOROBIPHENYL; POLYCHLORINATED BIPHENYL; POLYCHLORINATED DIBENZODIOXIN; POLYCHLORINATED DIBENZOFURAN; UNCLASSIFIED DRUG;

BIOMONITORING; BREASTFEEDING; GAS CHROMATOGRAPHY; MILK; NUTRITION; PCB; PCDD; PCDF; WORLD HEALTH ORGANIZATION;

ADULT; ARTICLE; BREAST MILK; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; FOOD CONTAMINATION; GEOGRAPHIC DISTRIBUTION; HUMAN; MAJOR CLINICAL STUDY; MASS FRAGMENTOGRAPHY; TOXICITY TESTING; TURKEY (REPUBLIC);

EURASIA; TURKEY;

EID: 68849130915     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2009.05.032     Document Type: Article

References (42)

1. Bakoglu M., Karademir A., and Durmusoglu E. Evaluation of PCDD/F levels in ambient air and soils and estimation of deposition rates in Kocaeli, Turkey. Chemosphere 59 (2005) 1373-1385
2. Bordajandi L.R., Abad E., and Gonzalez M.J. Occurrence of PCBs, PCDD/Fs, PBDEs and DDTs in Spanish breast milk: enantiomeric fraction of chiral PCBs. Chemosphere 70 (2008) 567-575
3. Çok I., and Satiroglu M.H. Polychlorinated biphenyl (PCB) levels of primiparous women in Turkey. Environ. Int. 30 (2004) 7-10
4. Çok I., Gorucu E., Şati{dotless}roglu M.H., and Cakmak G. Determination of polychlorinated biphenyl (PCB) levels in human milk samples from Turkish mothers. Bull. Environ. Contam. Toxicol. 70 (2003) 41-45
5. Çok I., Donmez M.K., Satiroglu M.H., Aydinuraz B., Henkelmann B., Kotalik J., and Schramm K.-W. Concentration of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and dioxin-like PCBs in human adipose tissue from Turkish men. Chemosphere 66 (2007) 1955-1961
6. Çok I., Donmez M.K., Satiroǧlu M.H., Aydinuraz B., Henkelmann B., Shen H., Kotalik J., and Schramm K.-W. Concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and dioxin-like PCBs in adipose tissue of infertile men. Arch. Environ. Contam. Toxicol. 55 (2008) 143-152
7. Costopoulou D., Vassiliadou I., Papadopoulos A., Makropoulos V., and Leondiadis L. Levels of dioxins, furans and PCBs in human serum and milk of people living in Greece. Chemosphere 65 (2006) 1462-1469
8. Erdogrul O., Covaci A., Kurtul N., and Schepens P. Levels of organohalogenated pollutants in human milk from Kahramanmaras region, Turkey. Environ. Int. 30 (2004) 659-666
9. Focant J.F., Pirard C., Thielen C., and De Pauw E. Levels and profiles of PCDDs, PCDFs and cPCBs in Belgian breast milk. Estimation of infant intake. Chemosphere 48 (2002) 763-770
10. Fries G.H. A review of the significance of animal food products as potential pathways of human exposure to dioxins. J. Anim. Sci. 73 (1995) 1639-1650
11. Fürst P., Fürst C., and Wilmers K. PCDDs and PCDFs in human milk - statistical evaluation of a 6-year survey. Chemosphere 25 (1992) 1029-1038
12. Guo Y.L., Hsu P.C., Hsu C.C., and Lambert G.H. Semen quality after prenatal exposure to polychlorinated biphenyls and dibenzofurans. Lancet 356 (2000) 1240-1241
13. Harden F.A., Toms L.M., Symons R., Fürst P., Berry Y., and Müller J.F. Evaluation of dioxin-like chemicals in pooled human milk samples collected in Australia. Chemosphere 67 (2007) 325-333
14. Hedley A.J., Wong T.W., Hui L.L., Malisch R., and Nelson E.A.S. Breast milk dioxins in Hong Kong and Pearl river delta. Environ. Health Perspect. 114 (2006) 202-208
15. Jensen A.A. Levels and trends of environmental chemicals in human milk. In: Jensen A.A., and Sorach S.A. (Eds). Chemical Contaminants in Human Milk (1991), CRC Press, Boca Raton, FL 24-198
16. Kiviranta H., Purkunen R., and Vartiainen T. Levels and trends of PCDD/Fs and PCBs in human milk in Finland. Chemosphere 38 (1999) 311-323
17. Kogevinas M. Human health effects of dioxin: cancer, reproductive and endocrine system effects. Hum. Reprod. Update 7 (2001) 331-339
18. Lakind J.S., Berlin C.M., and Naiman D.Q. Infant exposure to chemicals in breast milk in the United States: what we need to learn from a breast milk monitoring program. Environ. Health Perspect. 109 (2001) 75-88
19. Malisch R., and van Leeuwen R. Results of the WHO-coordinated exposure study on the levels of PCBs, PCDDs, and PCDFs in human milk. Organohal. Compd. 64 (2003) 140-143
20. McGregor D.B., Partensky C., Wilbourn J., and Rice J.M. An IARC evaluation of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans as risk factor in human carcinogenesis. Environ. Health Perspect. 106 (1998) 755-760
21. Needham L.L., and Wang R.Y. Analytic considerations for measuring environmental chemicals in breast milk. Environ. Health Perspect. 110 (2002) 317-324
22. Nouwen J., Cornelis C., De Fré R., Wevers M., Viaene P., Mensink C., Patyn J., Verschaeve L., Hooghe R., Maes A., Collier M., Schoeters G., Van Cleuvenbergen R., and Geuzens P. Health risk assessment of dioxin emissions from municipal waste incinerators: the Neerlandquarter (Wilrijk, Belgium). Chemosphere 43 (2001) 909-923
23. Papke O. PCDD/PCDF: human background data for Germany, a 10-year experience. Environ. Health Perspect. 106 Suppl. 2 (1998) 723-731
24. Paumgartten F.J., Cruz C.M., Chahoud I., Palavinskas R., and Mathar W. PCDDs, PCDFs, PCBs, and other organochlorine compounds in human milk from Rio de Janeiro, Brazil. Environ. Res. 83 (2000) 293-297
25. Pluim H.J., Kramer I., Van der Slikke J.W., Koppe J.G., and Olie K. Levels of PCDDs and PCDFs in human milk: dependence on several parameters and dietary habits. Chemosphere 26 (1993) 1889-1895
26. Reis M.F., Sampaio C., Aguiar P., Maurício M.J., Pereira M.J., and Päpke O. Biomonitoring of PCDD/Fs in populations living near Portuguese solid waste incinerators: levels in human milk. Chemosphere 67 (2007) 231-237
27. Safe S.H. Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit. Rev. Toxicol. 24 (1994) 87-149
28. Safe S.H. Modulation of gene expression and endocrine response pathways by 2,3,7,8, tetrachlorodi benzo-p-dioxin and related compounds. Pharmacol. Therapeut. 67 (1995) 247-281
29. Schuhmacher M., Domingo J.L., Kiviranta H., and Vartiainen T. Monitoring dioxins and furans in a population living near a hazardous waste incinerator: levels in breast milk. Chemosphere 57 (2004) 43-49
30. Sinkkonen S.P., and Paasivirta J. Degradation half-life times of PCDDs, PCDFs and PCBs for environmental fate modeling. Chemosphere 40 (2000) 943-949
31. Solomon G.M., and Weiss P.M. Chemical contaminants in breast milk: time trends and regional variability. Environ. Health Perspect. 110 (2002) 339-347
32. Telli-Karakoç F., Tolun L., Henkelmann B., Klimm C., Okay O., and Schramm K.-W. Polycyclic aromatic hydrocarbons (PAHs) and polyclorinated biphenyls (PCBs) distributions in the Bay of Marmara sea: Izmit Bay. Environ. Pollut. 119 (2002) 383-397
33. Todaka T., Hirakawa H., Kajiwara J., Hori T., Tobiishi K., Onozuka D., Kato S., Sasaki S., Nakajima S., Saijo Y., Sata F., Kishi R., Iida T., and Furue M. Concentrations of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like polychlorinated biphenyls in blood and breast milk collected from 60 mothers in Sapporo City, Japan. Chemosphere 72 (2008) 1152-1158
34. UNEP, 1999. Dioxin and Furan Inventories.National and Regional Emissions of PCDD/PCDF. UNEP Chemicals, Geneva, Switzerland.
35. US EPA, 1994. Health Assessment Document for 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and Related Compounds, vol. III.
36. Vallack H.W., Bakker D.J., Brandt I., Brostrom-Lunden E., Brouwer A., Bull K.R., Gough C., Guardans R., Holoubek I., Jansson B., Koch R., Kuylenstierna J., Lecloux A., Mackay D., McCurtcheon P., Mocarelli P., and Taalman R.D.F. Controlling persistent organic pollutants - what's next?. Environ. Toxicol. Pharmacol. 6 (1998) 143-175
37. van den Berg M., Birnbaum L.S., Bosveld A.T.C., Brunstrom B., Cook Ph., Feeley M., Giesy J.P., Hanberg A., Hasegawa R., Kennedy S.W., Kubiak T., Larsen J.C., Van Leeuwen F.X.R., Liem A.K.D., Nolt C., Peterson R.E., Poellinger L., Safe S., Schrenk D., Tillitt D., Tysklind M., Younes M., Wærn F., and Zacharewski T. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ. Health Perspect. 106 (1998) 775-792
38. WHO, 1989. In: Yrjänheikki, E. (Ed.), Levels of PCBs, PCDDs and PCDFs in Breast Milk: Results of WHO-Coordinated Interlaboratory Quality Control Studies and Analytical Field Studies. Environmental Health Series 34. World Health Organization Regional Office for Europe, Copenhagen.
39. WHO, 1996. Levels of PCBs, PCDDs and PCDFs in Human Milk: Second Round of WHO Coordinated Exposure Study. Environmental Health in Europe No 3. World Health Organization European Centre for Environment and Health, Bilthoven, Netherlands.
40. WHO, 1998. Assessment of the Health Risk of Dioxins: Re-evaluation of the Tolerable Daily Intake (TDI), May 25-29, 1998. WHO Consultation, Geneva, Switzerland.
41. Wittsiepe J., Schrey P., Ewers U., Selenka F., and Wilhelm M. Decrease of PCDD/F levels in human blood from Germany over the past ten years (1989-1998). Chemosphere 40 (2000) 1103-1109
42. Wittsiepe J., Fürst P., Schrey P., Lemm F., Kraft M., Eberwein G., Winneke G., and Wilhelm M. PCDD/F and dioxin-like PCB in human blood and milk from German mothers. Chemosphere 67 (2007) 286-294